| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HELZ | helicase with zinc finger | 0.0783314 |
| MEF2A | myocyte enhancer factor 2A | 0.0528808 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0507834 |
| FAM13A | family with sequence similarity 13, member A | 0.0461269 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0371453 |
| NDRG1 | N-myc downstream regulated 1 | 0.0368344 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.035436 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0345207 |
| WDR45B | WD repeat domain 45B | 0.0313249 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0312495 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0304705 |
| LSAMP | limbic system-associated membrane protein | 0.0302556 |
| PDE8A | phosphodiesterase 8A | 0.0291362 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0287225 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0283165 |
| QKI | QKI, KH domain containing, RNA binding | 0.0279674 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.027829 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0276567 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0274 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0269894 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0267282 |
| TFG | TRK-fused gene | 0.0266763 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0266409 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0263105 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0259966 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0254662 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0253029 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0252417 |
| FNBP1 | formin binding protein 1 | 0.0252413 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0247216 |
| SIK3 | SIK family kinase 3 | 0.0242917 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0242217 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0241707 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0239695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0239219 |
| COPA | coatomer protein complex, subunit alpha | 0.0234273 |
| RPLP0 | ribosomal protein, large, P0 | 0.0233685 |
| GOLGA4 | golgin A4 | 0.0230297 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0227005 |
| MAP4 | microtubule-associated protein 4 | 0.0226454 |
| USP3 | ubiquitin specific peptidase 3 | 0.0226345 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0224996 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0221834 |
| MSI2 | musashi RNA-binding protein 2 | 0.021962 |
| PHF20 | PHD finger protein 20 | 0.0216868 |
| RPL19 | ribosomal protein L19 | 0.021686 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0215616 |
| DMXL2 | Dmx-like 2 | 0.0214458 |
| RIOK3 | RIO kinase 3 | 0.0213719 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0213342 |
| RPL6 | ribosomal protein L6 | 0.0212074 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.02113 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0210733 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0209721 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0209205 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0207088 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0206684 |
| SMAD2 | SMAD family member 2 | 0.0206538 |
| CDON | cell adhesion associated, oncogene regulated | 0.0206075 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0205025 |
| SLMAP | sarcolemma associated protein | 0.0201855 |
| NRG1 | neuregulin 1 | 0.0201129 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.019991 |
| NUP58 | nucleoporin 58 | 0.0199156 |
| ATXN2 | ataxin 2 | 0.0198589 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0198249 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0197353 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0195768 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0194368 |
| LMO7 | LIM domain 7 | 0.0193661 |
| CORO1C | coronin, actin binding protein, 1C | 0.0192373 |
| RPL4 | ribosomal protein L4 | 0.0191448 |
| CCNL1 | cyclin L1 | 0.0191434 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0190604 |
| DYM | dymeclin | 0.0190281 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0189241 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0188261 |
| RAI1 | retinoic acid induced 1 | 0.0187426 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0187096 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0186674 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0185082 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0184757 |
| SDCBP | syndecan binding protein (syntenin) | 0.0183995 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0183842 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0182938 |
| WTAP | Wilms tumor 1 associated protein | 0.0180176 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0179974 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0179729 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0179263 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.017871 |
| PRKD1 | protein kinase D1 | 0.0178549 |
| USP25 | ubiquitin specific peptidase 25 | 0.0178108 |
| RNF145 | ring finger protein 145 | 0.0176893 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0176875 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor | 0.0176405 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0174901 |
| RPS23 | ribosomal protein S23 | 0.0173328 |
| SNX4 | sorting nexin 4 | 0.0172785 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0172704 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0172704 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.13761 |
| IGF2 | insulin-like growth factor 2 | -0.10123 |
| FMN1 | formin 1 | -0.0787375 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0742915 |
| SYT1 | synaptotagmin I | -0.0709266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0697421 |
| PLAT | plasminogen activator, tissue | -0.0676085 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0664066 |
| BPTF | bromodomain PHD finger transcription factor | -0.0552778 |
| TLE4 | transducin-like enhancer of split 4 | -0.0547907 |
| VCL | vinculin | -0.0519795 |
| RNF213 | ring finger protein 213 | -0.0491539 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0488271 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0449671 |
| LPIN1 | lipin 1 | -0.043665 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.042987 |
| RPL38 | ribosomal protein L38 | -0.0427407 |
| SMYD3 | SET and MYND domain containing 3 | -0.041733 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0398563 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0382441 |
| TPM1 | tropomyosin 1 (alpha) | -0.0367729 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0367388 |
| TMF1 | TATA element modulatory factor 1 | -0.0366226 |
| B2M | beta-2-microglobulin | -0.0359973 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0359189 |
| CLTC | clathrin, heavy chain (Hc) | -0.0349782 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0343567 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0342936 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0341049 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0334807 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0330131 |
| RPS2 | ribosomal protein S2 | -0.0327203 |
| ACTG1 | actin gamma 1 | -0.0326398 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0326245 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0317987 |
| VIM | vimentin | -0.0317886 |
| NREP | neuronal regeneration related protein | -0.0312502 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0312288 |
| FERMT2 | fermitin family member 2 | -0.0309317 |
| ANKRD17 | ankyrin repeat domain 17 | -0.030106 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0297138 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.02923 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0290133 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0285633 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0285111 |
| SON | SON DNA binding protein | -0.0280389 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.027855 |
| DST | dystonin | -0.0275419 |
| AUTS2 | autism susceptibility candidate 2 | -0.0272207 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0270511 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0269514 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0269284 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0268784 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0268042 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0266913 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0266285 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0259922 |
| CCDC57 | coiled-coil domain containing 57 | -0.0257438 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0254336 |
| RBM20 | RNA binding motif protein 20 | -0.0253463 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0250711 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0245936 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0245622 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0240317 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0239751 |
| RPL23 | ribosomal protein L23 | -0.0238664 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0236292 |
| CANX | calnexin | -0.0234101 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0233275 |
| PCBP2 | poly(rC) binding protein 2 | -0.0230016 |
| FHIT | fragile histidine triad | -0.0228668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.022865 |
| IFI44L | interferon-induced protein 44-like | -0.0226865 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0226444 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022613 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0224776 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0224351 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0223185 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0221828 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0218579 |
| IRS1 | insulin receptor substrate 1 | -0.021837 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0218166 |
| PLSCR1 | phospholipid scramblase 1 | -0.0217648 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0217646 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0217068 |
| GOLGB1 | golgin B1 | -0.021688 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0216702 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.021577 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0215692 |
| PHF3 | PHD finger protein 3 | -0.0214123 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | -0.0212871 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0211884 |
| ATRNL1 | attractin-like 1 | -0.0209114 |
| USP8 | ubiquitin specific peptidase 8 | -0.0206757 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0202629 |
| CA12 | carbonic anhydrase XII | -0.0201066 |
| MBTD1 | mbt domain containing 1 | -0.020063 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0200178 |
| NKTR | natural killer cell triggering receptor | -0.0199175 |
| FHL2 | four and a half LIM domains 2 | -0.0198656 |
