| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNIP1 | folliculin interacting protein 1 | 0.0937365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0786985 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0725057 |
| FNDC3B | fibronectin type III domain containing 3B | 0.06955 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0684152 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0671015 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0609658 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0607865 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0569279 |
| GOLGA4 | golgin A4 | 0.0563725 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0558322 |
| PGK1 | phosphoglycerate kinase 1 | 0.0550077 |
| ENO1 | enolase 1, (alpha) | 0.0546619 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0534261 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0505687 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0490163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.048899 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0488686 |
| PTEN | phosphatase and tensin homolog | 0.0485462 |
| RNF149 | ring finger protein 149 | 0.0483916 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0482357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0471514 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0454321 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0448855 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.043676 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0435046 |
| NDRG1 | N-myc downstream regulated 1 | 0.043436 |
| MSI2 | musashi RNA-binding protein 2 | 0.0433308 |
| SQSTM1 | sequestosome 1 | 0.0411254 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0410531 |
| MED13 | mediator complex subunit 13 | 0.0407918 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0404197 |
| WDR45B | WD repeat domain 45B | 0.0391424 |
| PTK2 | protein tyrosine kinase 2 | 0.0389437 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0386783 |
| SEC24D | SEC24 family member D | 0.0382561 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0381637 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0372802 |
| TFG | TRK-fused gene | 0.0372583 |
| PLIN2 | perilipin 2 | 0.0369174 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.036415 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0355888 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0348026 |
| HELZ | helicase with zinc finger | 0.0347276 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0346257 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0339035 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0336939 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.033637 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0334956 |
| FTL | ferritin, light polypeptide | 0.0332734 |
| OGA | O-GlcNAcase | 0.0329264 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0324241 |
| H1-0 | H1.0 linker histone | 0.0318797 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.031623 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0312195 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0307733 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0307384 |
| RLF | rearranged L-myc fusion | 0.0306835 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0306466 |
| YME1L1 | YME1-like 1 ATPase | 0.0304812 |
| ATXN1 | ataxin 1 | 0.0304604 |
| SCFD1 | sec1 family domain containing 1 | 0.0302032 |
| CD46 | CD46 molecule, complement regulatory protein | 0.030028 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.03 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0294474 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0293457 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0292699 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0292386 |
| USP34 | ubiquitin specific peptidase 34 | 0.0290976 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0289286 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.028816 |
| SUCO | SUN domain containing ossification factor | 0.0283597 |
| COPA | coatomer protein complex, subunit alpha | 0.0283534 |
| UBC | ubiquitin C | 0.0283231 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0282198 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278613 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.027754 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0276727 |
| SPATA13 | spermatogenesis associated 13 | 0.0274441 |
| FBXO42 | F-box protein 42 | 0.0270202 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0270167 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0269264 |
| CALU | calumenin | 0.0267571 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0266512 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.026647 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0266 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0264846 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0260476 |
| MORF4L2 | mortality factor 4 like 2 | 0.0260247 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0258653 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0256301 |
| NMU | neuromedin U | 0.0254512 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0254228 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0253019 |
| ERBIN | erbb2 interacting protein | 0.0252818 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0252596 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0252352 |
| TJP2 | tight junction protein 2 | 0.0250386 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0247784 |
| CLOCK | clock circadian regulator | 0.0245787 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.159397 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.112159 |
| MX1 | MX dynamin-like GTPase 1 | -0.0885097 |
| NCKAP5 | NCK-associated protein 5 | -0.0830184 |
| RNF43 | ring finger protein 43 | -0.0726865 |
| LCN2 | lipocalin 2 | -0.0715388 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0672073 |
| B2M | beta-2-microglobulin | -0.0671697 |
| LMO7 | LIM domain 7 | -0.0657386 |
| SP100 | SP100 nuclear antigen | -0.0614036 |
| PHF3 | PHD finger protein 3 | -0.0610938 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0601857 |
| TMC5 | transmembrane channel-like 5 | -0.0592999 |
| RNF213 | ring finger protein 213 | -0.0592947 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0586515 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0576991 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0576445 |
| IFNGR1 | interferon gamma receptor 1 | -0.0569216 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0568171 |
| MAP7 | microtubule-associated protein 7 | -0.0553452 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0546078 |
| BPTF | bromodomain PHD finger transcription factor | -0.0544287 |
| IL20RA | interleukin 20 receptor, alpha | -0.0530867 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0522072 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0507866 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0501657 |
| EPHB2 | EPH receptor B2 | -0.0496375 |
| MEIS2 | Meis homeobox 2 | -0.0486564 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0483915 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0480898 |
| VMP1 | vacuole membrane protein 1 | -0.0471512 |
| PLSCR1 | phospholipid scramblase 1 | -0.0460493 |
| RIGI | RNA sensor RIG-I | -0.0460056 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.045192 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0441919 |
| SMAD3 | SMAD family member 3 | -0.0439938 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0436799 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0430163 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0420026 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0416288 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0414958 |
| FMN1 | formin 1 | -0.0405807 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0404573 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0403612 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0397165 |
| TC2N | tandem C2 domains, nuclear | -0.0394146 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0393046 |
| TRERF1 | transcriptional regulating factor 1 | -0.0392467 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0389701 |
| ETV6 | ets variant 6 | -0.0383551 |
| TUFT1 | tuftelin 1 | -0.0383482 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0382652 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0377602 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.037368 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0369476 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.036863 |
| HDAC4 | histone deacetylase 4 | -0.03643 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0364235 |
| RBM39 | RNA binding motif protein 39 | -0.0361772 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0361688 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0352174 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0345468 |
| IRS2 | insulin receptor substrate 2 | -0.0343238 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0342046 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0339346 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0333144 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0328752 |
| SMYD3 | SET and MYND domain containing 3 | -0.0328396 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.032333 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0322469 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0322136 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0318442 |
| EFNB2 | ephrin-B2 | -0.0316195 |
| ADAR | adenosine deaminase, RNA-specific | -0.0314941 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0312173 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0310692 |
| CLYBL | citrate lyase beta like | -0.030989 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.0307131 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.030411 |
| MX2 | MX dynamin-like GTPase 2 | -0.0304097 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0301991 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.030151 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0300564 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0299226 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0299109 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0298641 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.029808 |
| ITGA1 | integrin, alpha 1 | -0.0294665 |
| IRF1 | interferon regulatory factor 1 | -0.0293041 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0289873 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0289216 |
| GOLGB1 | golgin B1 | -0.0287998 |
| EPCAM | epithelial cell adhesion molecule | -0.0287237 |
| TRIM44 | tripartite motif containing 44 | -0.0286931 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0286335 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0284591 |
| TRIM25 | tripartite motif containing 25 | -0.0284532 |
| RAD51B | RAD51 paralog B | -0.0282198 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.028202 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0280596 |
