| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.115904 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0913282 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0858615 |
| ANXA2 | annexin A2 | 0.0807294 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0806946 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0784461 |
| PGK1 | phosphoglycerate kinase 1 | 0.0765419 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0695595 |
| KRT18 | keratin 18, type I | 0.0681183 |
| DIAPH2 | diaphanous-related formin 2 | 0.065066 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0645347 |
| PTK2 | protein tyrosine kinase 2 | 0.063951 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0632582 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.062673 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0617358 |
| ZNF292 | zinc finger protein 292 | 0.0610155 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0596412 |
| ACTN4 | actinin, alpha 4 | 0.0592059 |
| AHNAK | AHNAK nucleoprotein | 0.0578937 |
| FAM13A | family with sequence similarity 13, member A | 0.0566259 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0519591 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0499149 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0485937 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0471412 |
| ENO1 | enolase 1, (alpha) | 0.0464834 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.046195 |
| RPL4 | ribosomal protein L4 | 0.0460155 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0448073 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0436934 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0435808 |
| DGKH | diacylglycerol kinase, eta | 0.0417753 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0410707 |
| USP54 | ubiquitin specific peptidase 54 | 0.0404626 |
| CCNY | cyclin Y | 0.039548 |
| TJP2 | tight junction protein 2 | 0.0380306 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0379 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0377997 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0370439 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0365561 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0364044 |
| TMEM123 | transmembrane protein 123 | 0.0359406 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0357699 |
| USP3 | ubiquitin specific peptidase 3 | 0.0357426 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0357278 |
| CHKA | choline kinase alpha | 0.0357254 |
| KRT19 | keratin 19, type I | 0.0355711 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0353224 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0352524 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0351265 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0347452 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0346584 |
| MMP7 | matrix metallopeptidase 7 | 0.0342529 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0338727 |
| LDHA | lactate dehydrogenase A | 0.0338626 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0333954 |
| KRT20 | keratin 20, type I | 0.0330166 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0329485 |
| MSI2 | musashi RNA-binding protein 2 | 0.0329077 |
| RNF145 | ring finger protein 145 | 0.0328522 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0319974 |
| ABLIM1 | actin binding LIM protein 1 | 0.0318332 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0317449 |
| HELZ | helicase with zinc finger | 0.0312431 |
| LAMA4 | laminin, alpha 4 | 0.0311313 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0308891 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0307907 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0303328 |
| FNIP1 | folliculin interacting protein 1 | 0.0302853 |
| PDE10A | phosphodiesterase 10A | 0.0302073 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0301916 |
| CA12 | carbonic anhydrase XII | 0.0298397 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0295774 |
| FRY | furry homolog (Drosophila) | 0.0294315 |
| H1-0 | H1.0 linker histone | 0.0291697 |
| SULF2 | sulfatase 2 | 0.0284991 |
| WASF2 | WAS protein family, member 2 | 0.0281623 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0275948 |
| PARD3 | par-3 family cell polarity regulator | 0.0274824 |
| ASPH | aspartate beta-hydroxylase | 0.0274604 |
| MYO18A | myosin XVIIIA | 0.0273793 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0273529 |
| HMGA2 | high mobility group AT-hook 2 | 0.0271527 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0270433 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0269465 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.0269353 |
| SDC4 | syndecan 4 | 0.0266154 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0261033 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0260725 |
| TCF12 | transcription factor 12 | 0.0260575 |
| TMEM65 | transmembrane protein 65 | 0.0259395 |
| BBX | bobby sox homolog (Drosophila) | 0.025892 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0257512 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0256665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256523 |
| WDR45B | WD repeat domain 45B | 0.0256479 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0256431 |
| RLF | rearranged L-myc fusion | 0.0253277 |
| APP | amyloid beta (A4) precursor protein | 0.0251909 |
| FAM162A | family with sequence similarity 162, member A | 0.0251683 |
| SQSTM1 | sequestosome 1 | 0.0250653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.145342 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.10248 |
| TXNRD1 | thioredoxin reductase 1 | -0.0992776 |
| RPS2 | ribosomal protein S2 | -0.0987743 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0975143 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0854394 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0817758 |
| RPS12 | ribosomal protein S12 | -0.0790826 |
| RPL23 | ribosomal protein L23 | -0.0765579 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0729902 |
| POTEF | POTE ankyrin domain family, member F | -0.0723821 |
| RPS19 | ribosomal protein S19 | -0.0722615 |
| PDZD8 | PDZ domain containing 8 | -0.0596925 |
| RPS8 | ribosomal protein S8 | -0.059624 |
| RPLP2 | ribosomal protein, large, P2 | -0.0586416 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0557797 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0531559 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0524709 |
| VCL | vinculin | -0.0518759 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0516365 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0515403 |
| FHL2 | four and a half LIM domains 2 | -0.0513173 |
| TJP1 | tight junction protein 1 | -0.0503027 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0501724 |
| RPL7 | ribosomal protein L7 | -0.0500642 |
| RPS3 | ribosomal protein S3 | -0.0499229 |
| EXPH5 | exophilin 5 | -0.0497508 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0484078 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0479322 |
| RND3 | Rho family GTPase 3 | -0.0475321 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.047349 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0466856 |
| TRIB1 | tribbles pseudokinase 1 | -0.046528 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0460189 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0451285 |
| HYOU1 | hypoxia up-regulated 1 | -0.0443885 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0441044 |
| BPTF | bromodomain PHD finger transcription factor | -0.0434925 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.042808 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0426956 |
| B2M | beta-2-microglobulin | -0.0411007 |
| RPL9 | ribosomal protein L9 | -0.0410548 |
| RPS13 | ribosomal protein S13 | -0.0409285 |
| RPL26 | ribosomal protein L26 | -0.040342 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0402503 |
| EGR1 | early growth response 1 | -0.0393618 |
| RPL28 | ribosomal protein L28 | -0.0393092 |
| NDRG1 | N-myc downstream regulated 1 | -0.0389728 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0387596 |
| RPLP1 | ribosomal protein, large, P1 | -0.0386598 |
| RPL11 | ribosomal protein L11 | -0.0385925 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0383483 |
| TUFT1 | tuftelin 1 | -0.0377938 |
| RBM39 | RNA binding motif protein 39 | -0.0371667 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0362358 |
| RPL35A | ribosomal protein L35a | -0.0360882 |
| RPL21 | ribosomal protein L21 | -0.0356936 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0348135 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0348069 |
| RPS17 | ribosomal protein S17 | -0.0344697 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.0341824 |
| RPL5 | ribosomal protein L5 | -0.0341725 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0339441 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0337382 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0327237 |
| ACTG1 | actin gamma 1 | -0.0323428 |
| RPS25 | ribosomal protein S25 | -0.0319045 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.031571 |
| PCBP2 | poly(rC) binding protein 2 | -0.03127 |
| RPS24 | ribosomal protein S24 | -0.0312693 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0311916 |
| BCL2L1 | BCL2-like 1 | -0.0310627 |
| RPL37 | ribosomal protein L37 | -0.03086 |
| RPL36A | ribosomal protein L36a | -0.030795 |
| RPL18 | ribosomal protein L18 | -0.0305372 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0303553 |
| NUP98 | nucleoporin 98kDa | -0.0299208 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0295723 |
| JMJD1C | jumonji domain containing 1C | -0.0294185 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0290776 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0289232 |
| RPL37A | ribosomal protein L37a | -0.0289213 |
| ZFP36 | ZFP36 ring finger protein | -0.0287776 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0287115 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0277169 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0275758 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0273309 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0271627 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0270436 |
| AGRN | agrin | -0.0269241 |
| CANX | calnexin | -0.0267956 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0266374 |
| RTN3 | reticulon 3 | -0.0266233 |
| GOLGB1 | golgin B1 | -0.0265129 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0264619 |
| MAGT1 | magnesium transporter 1 | -0.0264376 |
| RPL38 | ribosomal protein L38 | -0.0264259 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0261774 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0260619 |
| ATF6 | activating transcription factor 6 | -0.0260374 |
