| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.188293 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.181953 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.119655 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.100425 |
| AHNAK | AHNAK nucleoprotein | 0.0945444 |
| SLC35F3 | solute carrier family 35, member F3 | 0.093995 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0877375 |
| MEF2A | myocyte enhancer factor 2A | 0.0876665 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0847328 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0842167 |
| LMO7 | LIM domain 7 | 0.0825869 |
| PTK2 | protein tyrosine kinase 2 | 0.0786054 |
| RAI14 | retinoic acid induced 14 | 0.0728449 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0701771 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0666007 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0644946 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.064444 |
| FLNB | filamin B, beta | 0.0642955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0605401 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0591243 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0576478 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0571122 |
| LAMC2 | laminin, gamma 2 | 0.0535535 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0528114 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0500294 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0499866 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0496029 |
| FNIP1 | folliculin interacting protein 1 | 0.0480443 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0476566 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0474931 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0465716 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0457078 |
| MYOF | myoferlin | 0.0453179 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0449749 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0449488 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0446297 |
| SPAG9 | sperm associated antigen 9 | 0.0441995 |
| MYO10 | myosin X | 0.0441616 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.043364 |
| RASAL2 | RAS protein activator like 2 | 0.0423286 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0413362 |
| SMYD3 | SET and MYND domain containing 3 | 0.0412603 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0412333 |
| RBM39 | RNA binding motif protein 39 | 0.0409407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.040725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404804 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0404166 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.040067 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0400586 |
| PRELID2 | PRELI domain containing 2 | 0.0396777 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0388182 |
| SMAD3 | SMAD family member 3 | 0.0388025 |
| AMOTL1 | angiomotin like 1 | 0.038604 |
| CDK6 | cyclin-dependent kinase 6 | 0.0384163 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0383413 |
| ASPH | aspartate beta-hydroxylase | 0.038115 |
| UTRN | utrophin | 0.0381008 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0378437 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0360276 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0357784 |
| OGA | O-GlcNAcase | 0.0356393 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0355586 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0354445 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0351528 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0347443 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0341249 |
| JMJD1C | jumonji domain containing 1C | 0.0339556 |
| NEK7 | NIMA-related kinase 7 | 0.0338248 |
| ZNF292 | zinc finger protein 292 | 0.0337845 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0337423 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0333921 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0332061 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0321832 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0321269 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0320616 |
| SETD5 | SET domain containing 5 | 0.0317523 |
| PLS3 | plastin 3 | 0.0309287 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0308878 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0305909 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0297624 |
| TNS3 | tensin 3 | 0.0295822 |
| SLMAP | sarcolemma associated protein | 0.0291914 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291523 |
| H1-0 | H1.0 linker histone | 0.0289068 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.028812 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0285241 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0279269 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0276899 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0273892 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0271896 |
| COPA | coatomer protein complex, subunit alpha | 0.0268422 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0267996 |
| MTAP | methylthioadenosine phosphorylase | 0.0267422 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0265253 |
| AOPEP | aminopeptidase O (putative) | 0.0264158 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0263065 |
| ATXN1 | ataxin 1 | 0.0262144 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0261529 |
| KIAA1217 | KIAA1217 | 0.0259514 |
| SULF1 | sulfatase 1 | 0.0259312 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182124 |
| TMSB10 | thymosin beta 10 | -0.128932 |
| MT2A | metallothionein 2A | -0.115462 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0854659 |
| POTEF | POTE ankyrin domain family, member F | -0.0763051 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0628374 |
| RPS21 | ribosomal protein S21 | -0.0609007 |
| CLU | clusterin | -0.0608615 |
| B2M | beta-2-microglobulin | -0.0604698 |
| S100A10 | S100 calcium binding protein A10 | -0.0601685 |
| NDRG1 | N-myc downstream regulated 1 | -0.0600223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0583472 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0575628 |
| RPS19 | ribosomal protein S19 | -0.0560908 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0518546 |
| RPS13 | ribosomal protein S13 | -0.0496572 |
| FTL | ferritin, light polypeptide | -0.0486963 |
| RPS6 | ribosomal protein S6 | -0.0457791 |
| RPS8 | ribosomal protein S8 | -0.0449906 |
| MT1X | metallothionein 1X | -0.0433765 |
| S100A9 | S100 calcium binding protein A9 | -0.0432632 |
| S100A6 | S100 calcium binding protein A6 | -0.0428803 |
| PFN1 | profilin 1 | -0.040485 |
| RPL11 | ribosomal protein L11 | -0.040387 |
| S100A2 | S100 calcium binding protein A2 | -0.0400727 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0395555 |
| RPLP1 | ribosomal protein, large, P1 | -0.0394236 |
| EPHA2 | EPH receptor A2 | -0.0394156 |
| RPS3 | ribosomal protein S3 | -0.0392767 |
| RPL37 | ribosomal protein L37 | -0.0371827 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0368615 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0366021 |
| RPS12 | ribosomal protein S12 | -0.0354746 |
| GNAS | GNAS complex locus | -0.0353266 |
| LDHA | lactate dehydrogenase A | -0.0350589 |
| RPL23 | ribosomal protein L23 | -0.0344531 |
| RPL37A | ribosomal protein L37a | -0.0343388 |
| RPL12 | ribosomal protein L12 | -0.0341186 |
| TGM2 | transglutaminase 2 | -0.0340724 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0337585 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0337514 |
| EGR1 | early growth response 1 | -0.0325123 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0322401 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0320889 |
| LAMA5 | laminin, alpha 5 | -0.0317199 |
| RPL28 | ribosomal protein L28 | -0.0308522 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0308448 |
| S100A11 | S100 calcium binding protein A11 | -0.0303687 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0302496 |
| RPS23 | ribosomal protein S23 | -0.030212 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0301101 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.029932 |
| RPL32 | ribosomal protein L32 | -0.0298046 |
| RPL34 | ribosomal protein L34 | -0.0295778 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0293556 |
| RPL8 | ribosomal protein L8 | -0.0292478 |
| HLA-B | major histocompatibility complex, class I, B | -0.0290936 |
| ITGB4 | integrin, beta 4 | -0.0290454 |
| RPS27 | ribosomal protein S27 | -0.0287103 |
| RPL35 | ribosomal protein L35 | -0.0285741 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0284113 |
| GUK1 | guanylate kinase 1 | -0.0283491 |
| RPL9 | ribosomal protein L9 | -0.0279701 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0279387 |
| RPL36 | ribosomal protein L36 | -0.0277487 |
| RPL27A | ribosomal protein L27a | -0.0273422 |
| LMNA | lamin A/C | -0.0273121 |
| RPS25 | ribosomal protein S25 | -0.0270876 |
| HLA-A | major histocompatibility complex, class I, A | -0.0268905 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0262439 |
| RPL35A | ribosomal protein L35a | -0.0256385 |
| RPL36A | ribosomal protein L36a | -0.0256373 |
| RPL19 | ribosomal protein L19 | -0.0250486 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0250126 |
| PKM | pyruvate kinase, muscle | -0.0247719 |
| CST3 | cystatin C | -0.0246601 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0244311 |
| RPL31 | ribosomal protein L31 | -0.0243888 |
| TAGLN2 | transgelin 2 | -0.0239137 |
| TPI1 | triosephosphate isomerase 1 | -0.0238743 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0237396 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0234759 |
| RPS14 | ribosomal protein S14 | -0.0232287 |
| RPS29 | ribosomal protein S29 | -0.023179 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.022558 |
| YBX1 | Y box binding protein 1 | -0.0224909 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0223129 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022201 |
| RPL21 | ribosomal protein L21 | -0.0220642 |
| S100A4 | S100 calcium binding protein A4 | -0.0217434 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0213339 |
| RPL30 | ribosomal protein L30 | -0.0210654 |
| RPL26 | ribosomal protein L26 | -0.0210455 |
| IFI44 | interferon-induced protein 44 | -0.0208981 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0206474 |
| BSG | basigin (Ok blood group) | -0.0206433 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0204998 |
| RPLP0 | ribosomal protein, large, P0 | -0.0203709 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0203301 |
| EFHD2 | EF-hand domain family, member D2 | -0.0202396 |
