| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.195322 |
| FNDC3B | fibronectin type III domain containing 3B | 0.119593 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.109349 |
| NAV2 | neuron navigator 2 | 0.0899043 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0886023 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0800998 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0793839 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0757697 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0715993 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0642039 |
| ATP13A3 | ATPase type 13A3 | 0.0631753 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0593282 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0585917 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0568301 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.053181 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0525395 |
| ZNF292 | zinc finger protein 292 | 0.0504558 |
| SET | SET nuclear proto-oncogene | 0.0486714 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0483541 |
| HELZ | helicase with zinc finger | 0.0474557 |
| TPM3 | tropomyosin 3 | 0.0468824 |
| AFAP1 | actin filament associated protein 1 | 0.0428061 |
| PDS5B | PDS5 cohesin associated factor B | 0.0424918 |
| SQSTM1 | sequestosome 1 | 0.0424261 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.04201 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0414869 |
| MSN | moesin | 0.0408252 |
| RUNX1 | runt-related transcription factor 1 | 0.0407696 |
| MYOF | myoferlin | 0.0396739 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0392719 |
| GOLGA4 | golgin A4 | 0.0390866 |
| FLNB | filamin B, beta | 0.0390698 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0382573 |
| TGFB2 | transforming growth factor, beta 2 | 0.0375381 |
| DST | dystonin | 0.0366723 |
| SUCO | SUN domain containing ossification factor | 0.0365544 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0365448 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0362009 |
| KRT8 | keratin 8, type II | 0.0361215 |
| KIF13A | kinesin family member 13A | 0.0355969 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0354054 |
| NUP153 | nucleoporin 153kDa | 0.0353246 |
| SPAG9 | sperm associated antigen 9 | 0.0350642 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.034494 |
| NUP58 | nucleoporin 58 | 0.0343339 |
| PFKP | phosphofructokinase, platelet | 0.0342814 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0341918 |
| DTNA | dystrobrevin, alpha | 0.0341851 |
| NOP58 | NOP58 ribonucleoprotein | 0.0341137 |
| TMEM178B | transmembrane protein 178B | 0.0338298 |
| QKI | QKI, KH domain containing, RNA binding | 0.0337402 |
| DSCAM | Down syndrome cell adhesion molecule | 0.033687 |
| USP12 | ubiquitin specific peptidase 12 | 0.0335097 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0332803 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0329241 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0328995 |
| RYBP | RING1 and YY1 binding protein | 0.0327648 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0327059 |
| SLMAP | sarcolemma associated protein | 0.0318978 |
| CADM1 | cell adhesion molecule 1 | 0.0315849 |
| DENND4C | DENN/MADD domain containing 4C | 0.0314315 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0311919 |
| YEATS2 | YEATS domain containing 2 | 0.0310792 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0309122 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0308448 |
| UBC | ubiquitin C | 0.030711 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0306676 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0305094 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0303601 |
| TFG | TRK-fused gene | 0.0303253 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0302515 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.030106 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0300927 |
| BRD2 | bromodomain containing 2 | 0.03008 |
| PLK2 | polo-like kinase 2 | 0.0299785 |
| BBX | bobby sox homolog (Drosophila) | 0.0299601 |
| PLIN2 | perilipin 2 | 0.0298143 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0297884 |
| XPO1 | exportin 1 | 0.0296804 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.029537 |
| ATP11B | ATPase, class VI, type 11B | 0.0292956 |
| SETD5 | SET domain containing 5 | 0.0292271 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292106 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0291019 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0286951 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0286762 |
| MEF2A | myocyte enhancer factor 2A | 0.0285783 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0285735 |
| FRMD6 | FERM domain containing 6 | 0.0283683 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281219 |
| SBF2 | SET binding factor 2 | 0.0279921 |
| TPD52 | tumor protein D52 | 0.0279899 |
| RNF145 | ring finger protein 145 | 0.0278027 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0277569 |
| ENO1 | enolase 1, (alpha) | 0.0276664 |
| FOSL1 | FOS-like antigen 1 | 0.0275655 |
| GSK3B | glycogen synthase kinase 3 beta | 0.027432 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.027204 |
| ANO6 | anoctamin 6 | 0.0271915 |
| PDE10A | phosphodiesterase 10A | 0.0270997 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.138789 |
| MT2A | metallothionein 2A | -0.138032 |
| EXT1 | exostosin glycosyltransferase 1 | -0.137829 |
| CD44 | CD44 molecule (Indian blood group) | -0.0881284 |
| NDRG1 | N-myc downstream regulated 1 | -0.0776891 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0675325 |
| MT1X | metallothionein 1X | -0.0669162 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0646228 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0625152 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0599391 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0567958 |
| HLA-C | major histocompatibility complex, class I, C | -0.0567947 |
| GLIS3 | GLIS family zinc finger 3 | -0.055887 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.054772 |
| FTL | ferritin, light polypeptide | -0.0498301 |
| ACTG1 | actin gamma 1 | -0.0478125 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0457908 |
| TMSB10 | thymosin beta 10 | -0.045757 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0457427 |
| RPL35A | ribosomal protein L35a | -0.0429478 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0412217 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0369336 |
| OSMR | oncostatin M receptor | -0.0360752 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0355569 |
| PODXL | podocalyxin-like | -0.0350097 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0347515 |
| ERBIN | erbb2 interacting protein | -0.0345238 |
| GOLGA3 | golgin A3 | -0.0342822 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0340143 |
| PLSCR1 | phospholipid scramblase 1 | -0.0339233 |
| ZNF432 | zinc finger protein 432 | -0.0339084 |
| CAVIN1 | caveolae associated protein 1 | -0.0336544 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0324404 |
| INTS6 | integrator complex subunit 6 | -0.0322248 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0321688 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0315346 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0313563 |
| VCL | vinculin | -0.0311691 |
| RPL23 | ribosomal protein L23 | -0.0310555 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0309169 |
| TUBB | tubulin, beta class I | -0.0299536 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.029763 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0294377 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0293593 |
| RPS6 | ribosomal protein S6 | -0.0290499 |
| RANBP17 | RAN binding protein 17 | -0.028713 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283868 |
| DIAPH3 | diaphanous-related formin 3 | -0.0274994 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0270566 |
| RPLP2 | ribosomal protein, large, P2 | -0.0262523 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0260476 |
| FLNA | filamin A, alpha | -0.025574 |
| ARF1 | ADP-ribosylation factor 1 | -0.0254948 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0250778 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0249599 |
| NABP1 | nucleic acid binding protein 1 | -0.0248662 |
| BPTF | bromodomain PHD finger transcription factor | -0.0240044 |
| LOX | lysyl oxidase | -0.0239577 |
| GANAB | glucosidase, alpha; neutral AB | -0.0236803 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.023477 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0233451 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0233221 |
| PDCD6 | programmed cell death 6 | -0.0232187 |
| FUS | FUS RNA binding protein | -0.0228666 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0226633 |
| S100A10 | S100 calcium binding protein A10 | -0.0224204 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0221816 |
| EGR1 | early growth response 1 | -0.02198 |
| FHL2 | four and a half LIM domains 2 | -0.0219134 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0219009 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0215165 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0212256 |
| RPL34 | ribosomal protein L34 | -0.0211214 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0210507 |
| TBCA | tubulin folding cofactor A | -0.02065 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0205409 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0203813 |
| RPL37 | ribosomal protein L37 | -0.0201261 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0200387 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0199789 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0199768 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0197805 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0196358 |
| RPL12 | ribosomal protein L12 | -0.0194732 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0192719 |
| CTSD | cathepsin D | -0.0191864 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0191264 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0190801 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0190412 |
| CCND1 | cyclin D1 | -0.0190292 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0190042 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0189749 |
| HMGB1 | high mobility group box 1 | -0.0189695 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0189193 |
| E2F3 | E2F transcription factor 3 | -0.0189111 |
| LMNA | lamin A/C | -0.0189007 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0188157 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0188092 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0184726 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0183855 |
