| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | 0.143082 |
| FNDC3B | fibronectin type III domain containing 3B | 0.100032 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0975436 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0911418 |
| NPSR1 | neuropeptide S receptor 1 | 0.0845259 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.075532 |
| H1-0 | H1.0 linker histone | 0.0693379 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0691779 |
| KRT8 | keratin 8, type II | 0.0684367 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0657784 |
| RAB1A | RAB1A, member RAS oncogene family | 0.063111 |
| FRMD5 | FERM domain containing 5 | 0.0604671 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0599439 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0594927 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0587072 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0577205 |
| ZNF292 | zinc finger protein 292 | 0.056124 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0554273 |
| S100A6 | S100 calcium binding protein A6 | 0.0526188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0524026 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0510215 |
| FAM13A | family with sequence similarity 13, member A | 0.0504494 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0501081 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0488792 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0487561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0482809 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0470339 |
| TES | testin LIM domain protein | 0.045478 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0450369 |
| FNIP1 | folliculin interacting protein 1 | 0.0445317 |
| KRT18 | keratin 18, type I | 0.0441677 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0437065 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0433628 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0429081 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0428835 |
| AHNAK | AHNAK nucleoprotein | 0.0424009 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0418631 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0418135 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0417516 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0414623 |
| SETD5 | SET domain containing 5 | 0.0413716 |
| HM13 | histocompatibility (minor) 13 | 0.0407849 |
| JMJD1C | jumonji domain containing 1C | 0.0405133 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0402811 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0401609 |
| CCNY | cyclin Y | 0.039985 |
| COG5 | component of oligomeric golgi complex 5 | 0.0398415 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0394195 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0392237 |
| SBF2 | SET binding factor 2 | 0.0391335 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0390199 |
| ANXA11 | annexin A11 | 0.0389527 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.038625 |
| RNF145 | ring finger protein 145 | 0.0378428 |
| RPL4 | ribosomal protein L4 | 0.037468 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0373103 |
| CHKA | choline kinase alpha | 0.0366099 |
| ANLN | anillin, actin binding protein | 0.0364883 |
| ATXN1 | ataxin 1 | 0.036207 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0361902 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0360052 |
| LAMB3 | laminin, beta 3 | 0.0355246 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0354793 |
| HDAC9 | histone deacetylase 9 | 0.0350709 |
| RIOK3 | RIO kinase 3 | 0.0350351 |
| SCFD1 | sec1 family domain containing 1 | 0.0350139 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0348562 |
| SNX13 | sorting nexin 13 | 0.0347501 |
| FOXO3 | forkhead box O3 | 0.0347273 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0346115 |
| GOLGA4 | golgin A4 | 0.0342859 |
| SUCO | SUN domain containing ossification factor | 0.034073 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0339179 |
| EZR | ezrin | 0.0338629 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0334358 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0331488 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0328763 |
| PGK1 | phosphoglycerate kinase 1 | 0.032821 |
| AREG | amphiregulin | 0.0327727 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0326409 |
| OGA | O-GlcNAcase | 0.0325863 |
| WDR45B | WD repeat domain 45B | 0.0319504 |
| WAC | WW domain containing adaptor with coiled-coil | 0.031916 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0317749 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0316921 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.031484 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0312894 |
| ARFGEF3 | ARFGEF family member 3 | 0.0311279 |
| ACTG1 | actin gamma 1 | 0.0307939 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0305567 |
| RTN4 | reticulon 4 | 0.0304841 |
| CDC42SE2 | CDC42 small effector 2 | 0.0303878 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0302993 |
| MEF2A | myocyte enhancer factor 2A | 0.0299666 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0298587 |
| NUP58 | nucleoporin 58 | 0.029817 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0296851 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0295118 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0291098 |
| PARD3 | par-3 family cell polarity regulator | 0.028966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMC5 | transmembrane channel-like 5 | -0.0933801 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0864838 |
| LMO7 | LIM domain 7 | -0.0833936 |
| B2M | beta-2-microglobulin | -0.0817131 |
| SEPTIN9 | septin 9 | -0.0616268 |
| RNF213 | ring finger protein 213 | -0.0514997 |
| EPCAM | epithelial cell adhesion molecule | -0.0468855 |
| BPTF | bromodomain PHD finger transcription factor | -0.0457254 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0443854 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.044024 |
| ATM | ATM serine/threonine kinase | -0.0437438 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0402702 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0398845 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0386941 |
| TUBB4B | tubulin, beta 4B class IVb | -0.038426 |
| RPS2 | ribosomal protein S2 | -0.0383937 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0379481 |
| S100A10 | S100 calcium binding protein A10 | -0.0379029 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0367125 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0365227 |
| RRBP1 | ribosome binding protein 1 | -0.0362278 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0360184 |
| HLA-C | major histocompatibility complex, class I, C | -0.0360026 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0347099 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.034303 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0337667 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335009 |
| NDRG1 | N-myc downstream regulated 1 | -0.0330709 |
| RNF43 | ring finger protein 43 | -0.032802 |
| AHR | aryl hydrocarbon receptor | -0.0326388 |
| PLSCR1 | phospholipid scramblase 1 | -0.0321858 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0313287 |
| TMEM45B | transmembrane protein 45B | -0.0307281 |
| LMNA | lamin A/C | -0.0302643 |
| ATF5 | activating transcription factor 5 | -0.0293805 |
| MUC17 | mucin 17, cell surface associated | -0.029323 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0291141 |
| ASPH | aspartate beta-hydroxylase | -0.0289638 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0280754 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0268313 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0268202 |
| RIGI | RNA sensor RIG-I | -0.0265976 |
| PKM | pyruvate kinase, muscle | -0.0264715 |
| MYO1D | myosin ID | -0.0260812 |
| POF1B | premature ovarian failure, 1B | -0.0260744 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0256671 |
| RPS6 | ribosomal protein S6 | -0.0256414 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | -0.0256256 |
| SMAD3 | SMAD family member 3 | -0.025446 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0250486 |
| MX1 | MX dynamin-like GTPase 1 | -0.0246408 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0237022 |
| RPL23 | ribosomal protein L23 | -0.0236912 |
| TRIM56 | tripartite motif containing 56 | -0.0234383 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.023396 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0233313 |
| KLF6 | Kruppel-like factor 6 | -0.0231457 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0231249 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0230113 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0227356 |
| XAF1 | XIAP associated factor 1 | -0.0226375 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0224408 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0220927 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0220684 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0219509 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0218124 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0216676 |
| TFRC | transferrin receptor | -0.0214982 |
| ONECUT3 | one cut homeobox 3 | -0.0213751 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0212524 |
| FAT1 | FAT atypical cadherin 1 | -0.0211747 |
| AGR2 | anterior gradient 2 | -0.0211183 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0209927 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0209664 |
| INSIG1 | insulin induced gene 1 | -0.0208874 |
| ATAD5 | ATPase family, AAA domain containing 5 | -0.0208762 |
| MX2 | MX dynamin-like GTPase 2 | -0.020686 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0206191 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0204175 |
| GPHN | gephyrin | -0.0203725 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0202705 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0201983 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0200135 |
| RPL9 | ribosomal protein L9 | -0.0199642 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0199419 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0198665 |
| ABR | active BCR-related | -0.0197701 |
| SLFN5 | schlafen family member 5 | -0.0196743 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.01966 |
| SFPQ | splicing factor proline/glutamine-rich | -0.019655 |
| FRY | furry homolog (Drosophila) | -0.0196427 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0195775 |
| MTAP | methylthioadenosine phosphorylase | -0.0195684 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0194228 |
| RESF1 | retroelement silencing factor 1 | -0.0192573 |
| TGFA | transforming growth factor, alpha | -0.019185 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0189781 |
| RPL35A | ribosomal protein L35a | -0.0189734 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.0188841 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0187513 |
