| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF145 | ring finger protein 145 | 0.0969122 |
| FAM13A | family with sequence similarity 13, member A | 0.0738168 |
| EREG | epiregulin | 0.0671571 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0639844 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0595584 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0539836 |
| TXNIP | thioredoxin interacting protein | 0.0520285 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0504242 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.049848 |
| MED13L | mediator complex subunit 13-like | 0.0486021 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.046772 |
| ZNF292 | zinc finger protein 292 | 0.0462646 |
| COPA | coatomer protein complex, subunit alpha | 0.0453647 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0432335 |
| TFG | TRK-fused gene | 0.0392253 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0388764 |
| CCNY | cyclin Y | 0.0385489 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0378216 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0371939 |
| NUP58 | nucleoporin 58 | 0.0371413 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0363272 |
| RPL21 | ribosomal protein L21 | 0.0361679 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0353844 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352997 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0346004 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0343003 |
| SETD5 | SET domain containing 5 | 0.0341358 |
| GOLGA4 | golgin A4 | 0.0337808 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0333205 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0325033 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0319169 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0309405 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0309209 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0308119 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0296909 |
| S100P | S100 calcium binding protein P | 0.02967 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0286216 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0282234 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0281046 |
| USP3 | ubiquitin specific peptidase 3 | 0.0279944 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0276544 |
| CCNL1 | cyclin L1 | 0.0275276 |
| HELZ | helicase with zinc finger | 0.0274729 |
| H2AC6 | H2A clustered histone 6 | 0.0274575 |
| VEGFA | vascular endothelial growth factor A | 0.0257464 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0255771 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0255641 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0253213 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0252884 |
| CDC73 | cell division cycle 73 | 0.0252715 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.024766 |
| ETNK1 | ethanolamine kinase 1 | 0.0246502 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0246373 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0245405 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0245271 |
| SUCO | SUN domain containing ossification factor | 0.024389 |
| NCKAP1 | NCK-associated protein 1 | 0.0237865 |
| RREB1 | ras responsive element binding protein 1 | 0.0237262 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0235279 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0234546 |
| SLMAP | sarcolemma associated protein | 0.0233804 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0231345 |
| SRP54 | signal recognition particle 54kDa | 0.022858 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0226714 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0226486 |
| SEC24D | SEC24 family member D | 0.0226381 |
| RPL3 | ribosomal protein L3 | 0.0218649 |
| KRT18 | keratin 18, type I | 0.0218513 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0217782 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.021766 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0216431 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0216184 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0214342 |
| SPPL3 | signal peptide peptidase like 3 | 0.0212869 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0212824 |
| WDR45B | WD repeat domain 45B | 0.0210718 |
| RLF | rearranged L-myc fusion | 0.0208426 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0207611 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0204526 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0203542 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0203355 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.020306 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0200441 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0199644 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0199263 |
| YBX1 | Y box binding protein 1 | 0.0197143 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0196449 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0196074 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.019591 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0194618 |
| LRRC1 | leucine rich repeat containing 1 | 0.0193791 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0191296 |
| MXD1 | MAX dimerization protein 1 | 0.0187916 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0186302 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0184117 |
| CDC42SE2 | CDC42 small effector 2 | 0.0182893 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0181592 |
| TPD52 | tumor protein D52 | 0.0181209 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.018118 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0181151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.226533 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.178013 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.168483 |
| AHNAK | AHNAK nucleoprotein | -0.106564 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.105336 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0969874 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0943079 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0899758 |
| FAT1 | FAT atypical cadherin 1 | -0.0869643 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0817152 |
| RPS27A | ribosomal protein S27a | -0.0792736 |
| MYO1E | myosin IE | -0.0789452 |
| TMSB10 | thymosin beta 10 | -0.0777066 |
| NPSR1 | neuropeptide S receptor 1 | -0.0717208 |
| UBC | ubiquitin C | -0.0712717 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.070139 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0695205 |
| ONECUT3 | one cut homeobox 3 | -0.0687345 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.059754 |
| ITGA6 | integrin, alpha 6 | -0.0561804 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0555893 |
| CANX | calnexin | -0.0552602 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0552033 |
| ACTG1 | actin gamma 1 | -0.0536567 |
| TPM4 | tropomyosin 4 | -0.0533523 |
| RPL23 | ribosomal protein L23 | -0.0524992 |
| PKM | pyruvate kinase, muscle | -0.0510906 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0501408 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0499617 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0482637 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0477251 |
| ASPH | aspartate beta-hydroxylase | -0.0475258 |
| S100A6 | S100 calcium binding protein A6 | -0.0472158 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0463688 |
| ENO1 | enolase 1, (alpha) | -0.0457908 |
| JUN | jun proto-oncogene | -0.044201 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0418839 |
| EPCAM | epithelial cell adhesion molecule | -0.0417261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0415467 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0408826 |
| FHIT | fragile histidine triad | -0.0407415 |
| EZR | ezrin | -0.040687 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0403018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0401544 |
| CD44 | CD44 molecule (Indian blood group) | -0.0388358 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0386676 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0382873 |
| SMYD3 | SET and MYND domain containing 3 | -0.0377982 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0354288 |
| APP | amyloid beta (A4) precursor protein | -0.0350279 |
| RPL35A | ribosomal protein L35a | -0.0350013 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.034956 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0345532 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344673 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0341869 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0339393 |
| PATJ | PATJ crumbs cell polarity complex component | -0.033842 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0338279 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0337457 |
| PCBP2 | poly(rC) binding protein 2 | -0.033629 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335738 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0331945 |
| DIAPH2 | diaphanous-related formin 2 | -0.0331071 |
| CALR | calreticulin | -0.0329474 |
| EPHB2 | EPH receptor B2 | -0.0329262 |
| CCND1 | cyclin D1 | -0.0329143 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0326404 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0325751 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0322474 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0320345 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0318272 |
| FOXP1 | forkhead box P1 | -0.031203 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0311153 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0305312 |
| MT2A | metallothionein 2A | -0.0303695 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0303516 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0303042 |
| BPTF | bromodomain PHD finger transcription factor | -0.0302711 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0301501 |
| RPS6 | ribosomal protein S6 | -0.0297177 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0296955 |
| TSC22D1 | TSC22 domain family, member 1 | -0.029646 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0295634 |
| PIGR | polymeric immunoglobulin receptor | -0.0295132 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029256 |
| LMNA | lamin A/C | -0.0291867 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0286767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0282118 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0276244 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0271726 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0269175 |
| FRMD5 | FERM domain containing 5 | -0.0269093 |
| POTEF | POTE ankyrin domain family, member F | -0.026791 |
| KIF5B | kinesin family member 5B | -0.0266533 |
| ACTN4 | actinin, alpha 4 | -0.0263954 |
| RPL34 | ribosomal protein L34 | -0.0263794 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0263183 |
| RNF213 | ring finger protein 213 | -0.0262983 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0262942 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0260319 |
