| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0823509 |
| DST | dystonin | 0.0679667 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0679489 |
| CAPRIN2 | caprin family member 2 | 0.0651832 |
| FNIP1 | folliculin interacting protein 1 | 0.0562247 |
| EFNA5 | ephrin-A5 | 0.0549302 |
| FMNL2 | formin-like 2 | 0.0538415 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0493171 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0460635 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0434978 |
| RPL3 | ribosomal protein L3 | 0.0404097 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0395237 |
| ZNF292 | zinc finger protein 292 | 0.0391937 |
| TXNIP | thioredoxin interacting protein | 0.03836 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0380214 |
| TPM3 | tropomyosin 3 | 0.0371105 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0345414 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0330716 |
| PRELID2 | PRELI domain containing 2 | 0.0323581 |
| RNF145 | ring finger protein 145 | 0.031055 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0301699 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.030035 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0292106 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0289007 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0283603 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0271042 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0262937 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0262573 |
| CDK19 | cyclin-dependent kinase 19 | 0.0259152 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0256423 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0248715 |
| SETD5 | SET domain containing 5 | 0.0243306 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0239883 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0238318 |
| RPL21 | ribosomal protein L21 | 0.0233804 |
| HELZ | helicase with zinc finger | 0.0231309 |
| COPA | coatomer protein complex, subunit alpha | 0.0230295 |
| MEF2A | myocyte enhancer factor 2A | 0.0225298 |
| ATXN2 | ataxin 2 | 0.0218641 |
| MSN | moesin | 0.0218379 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0215652 |
| COG5 | component of oligomeric golgi complex 5 | 0.0214754 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0206045 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0205767 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0205744 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0204623 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0204353 |
| RASAL2 | RAS protein activator like 2 | 0.0203787 |
| UBC | ubiquitin C | 0.0201562 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0200944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0199283 |
| BRD2 | bromodomain containing 2 | 0.0196152 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0193642 |
| EXOC4 | exocyst complex component 4 | 0.0193515 |
| RPL4 | ribosomal protein L4 | 0.019313 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0192348 |
| RAD51B | RAD51 paralog B | 0.0191725 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0191637 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0191098 |
| GOLGA4 | golgin A4 | 0.0190063 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0188856 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0188798 |
| DENR | density-regulated protein | 0.0187105 |
| HDGF | hepatoma-derived growth factor | 0.0186692 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0183899 |
| SET | SET nuclear proto-oncogene | 0.0183119 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0181875 |
| ZNF451 | zinc finger protein 451 | 0.0181549 |
| FAM168A | family with sequence similarity 168, member A | 0.0180524 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.018046 |
| PTK2 | protein tyrosine kinase 2 | 0.0180256 |
| OGA | O-GlcNAcase | 0.0179877 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0179666 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0179573 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0179171 |
| NBAS | neuroblastoma amplified sequence | 0.0177966 |
| RRM2 | ribonucleotide reductase M2 | 0.017675 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0175588 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0175081 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0174774 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173117 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0171767 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0171007 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0170768 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.017001 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0169416 |
| SBF2 | SET binding factor 2 | 0.0169319 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0166467 |
| SRPK2 | SRSF protein kinase 2 | 0.0165792 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.016558 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0165286 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0165142 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0164922 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0164606 |
| ZNF148 | zinc finger protein 148 | 0.0164304 |
| TNS3 | tensin 3 | 0.0164023 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.016359 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0162248 |
| PGM3 | phosphoglucomutase 3 | 0.0160816 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0159738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.316388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156418 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.13839 |
| MT2A | metallothionein 2A | -0.132835 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.121692 |
| TXNRD1 | thioredoxin reductase 1 | -0.113318 |
| TMSB10 | thymosin beta 10 | -0.109192 |
| LOC112694756 | uncharaterized LOC112694756 | -0.106137 |
| RPL35A | ribosomal protein L35a | -0.0988876 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.09558 |
| CD44 | CD44 molecule (Indian blood group) | -0.0903675 |
| ACTG1 | actin gamma 1 | -0.0851992 |
| TP63 | tumor protein p63 | -0.0819224 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0779072 |
| HLA-B | major histocompatibility complex, class I, B | -0.0664806 |
| TMSB4X | thymosin beta 4, X-linked | -0.0656148 |
| RIGI | RNA sensor RIG-I | -0.0624236 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0598844 |
| RAI1 | retinoic acid induced 1 | -0.0597748 |
| KLF6 | Kruppel-like factor 6 | -0.0577065 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0530661 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0528066 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.052396 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0521267 |
| EGR1 | early growth response 1 | -0.0517612 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0516762 |
| CANX | calnexin | -0.0508387 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0504076 |
| PTMA | prothymosin, alpha | -0.0501351 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0493743 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0491558 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.04804 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0474687 |
| HMGA1 | high mobility group AT-hook 1 | -0.0466229 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0453168 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0452891 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0437343 |
| SRGN | serglycin | -0.0434608 |
| AHNAK | AHNAK nucleoprotein | -0.0434364 |
| RGS4 | regulator of G-protein signaling 4 | -0.0429898 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0414312 |
| MT1E | metallothionein 1E | -0.0413655 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0411919 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.041094 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0410609 |
| OSMR | oncostatin M receptor | -0.0397911 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0391257 |
| RPS24 | ribosomal protein S24 | -0.0386203 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0383711 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0377574 |
| JUN | jun proto-oncogene | -0.0370479 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0368972 |
| EMP1 | epithelial membrane protein 1 | -0.0367364 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0367294 |
| CAVIN1 | caveolae associated protein 1 | -0.0365863 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0365797 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0365454 |
| ARF1 | ADP-ribosylation factor 1 | -0.0358233 |
| LDHA | lactate dehydrogenase A | -0.0355669 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0354804 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0351081 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0342277 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0341133 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0338637 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0330933 |
| PYGB | phosphorylase, glycogen; brain | -0.0330672 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0328634 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0328493 |
| RPL38 | ribosomal protein L38 | -0.0326505 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326459 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0324517 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0323848 |
| RPL23 | ribosomal protein L23 | -0.0323076 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0315107 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0313918 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0313822 |
| GNAS | GNAS complex locus | -0.0313322 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0311982 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0311831 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0309207 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0308683 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0307157 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0305552 |
| RPL26 | ribosomal protein L26 | -0.0305482 |
| MT1X | metallothionein 1X | -0.0302476 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0299876 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0296313 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029385 |
| EZR | ezrin | -0.029301 |
| PLSCR1 | phospholipid scramblase 1 | -0.0292277 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0292051 |
| PODXL | podocalyxin-like | -0.0290728 |
| RNF213 | ring finger protein 213 | -0.0290202 |
| FERMT1 | fermitin family member 1 | -0.0289626 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.028822 |
| PYGL | phosphorylase, glycogen, liver | -0.0288216 |
| FBXO11 | F-box protein 11 | -0.0287926 |
| TMEM41B | transmembrane protein 41B | -0.0286377 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.028435 |
| HDLBP | high density lipoprotein binding protein | -0.0282711 |
