| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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102 genes differentially expressed following the Imiquimod (maleate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.301197 |
| DENND4A | DENN/MADD domain containing 4A | 0.17171 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.158606 |
| IGF2 | insulin-like growth factor 2 | 0.156153 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.142297 |
| EXT1 | exostosin glycosyltransferase 1 | 0.136965 |
| MEF2A | myocyte enhancer factor 2A | 0.134464 |
| CLIC4 | chloride intracellular channel 4 | 0.134282 |
| TPD52 | tumor protein D52 | 0.128365 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.125928 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.115593 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.112776 |
| TBC1D22A | TBC1 domain family, member 22A | 0.107715 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.103393 |
| TMEM87A | transmembrane protein 87A | 0.0953022 |
| PGK1 | phosphoglycerate kinase 1 | 0.0943664 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0930667 |
| VMP1 | vacuole membrane protein 1 | 0.0823745 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.081979 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0808248 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0799953 |
| MYO6 | myosin VI | 0.0797512 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0774644 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0719417 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.069098 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0665113 |
| GLG1 | golgi glycoprotein 1 | 0.0661028 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0591194 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0571814 |
| JMJD1C | jumonji domain containing 1C | 0.0559157 |
| RPS6 | ribosomal protein S6 | 0.04657 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0393158 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0364154 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0360623 |
| RPS16 | ribosomal protein S16 | 0.0355767 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0347535 |
| ETNK1 | ethanolamine kinase 1 | 0.0297603 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0255519 |
| FLNB | filamin B, beta | 0.0246104 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0243078 |
| DSPP | dentin sialophosphoprotein | 0.0229478 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0144716 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0135239 |
| USP34 | ubiquitin specific peptidase 34 | 0.0129769 |
| LDHA | lactate dehydrogenase A | 0.00989201 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00367601 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.00230612 |
| FN1 | fibronectin 1 | 0.00165752 |
| GOLGA4 | golgin A4 | 7.72466E-4 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 4.11606E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.317244 |
| VIM | vimentin | -0.127892 |
| NDRG1 | N-myc downstream regulated 1 | -0.118666 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.106278 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.104239 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.101807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.101082 |
| PARD3 | par-3 family cell polarity regulator | -0.0902952 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0856378 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0828315 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0815744 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0789434 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0766349 |
| PTMA | prothymosin, alpha | -0.0746891 |
| RPLP1 | ribosomal protein, large, P1 | -0.0702292 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0661105 |
| FNIP1 | folliculin interacting protein 1 | -0.0600597 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0537444 |
| SBF2 | SET binding factor 2 | -0.052858 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0502181 |
| NAV2 | neuron navigator 2 | -0.0501024 |
| ACTG1 | actin gamma 1 | -0.0490082 |
| RPL23 | ribosomal protein L23 | -0.048751 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0476278 |
| PTK2 | protein tyrosine kinase 2 | -0.0475201 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0471095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0470024 |
| PRKCA | protein kinase C, alpha | -0.0422764 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0418605 |
| ASPH | aspartate beta-hydroxylase | -0.0417444 |
| GPC6 | glypican 6 | -0.0411027 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.040091 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.038547 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0367004 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0338166 |
| TMSB10 | thymosin beta 10 | -0.0327887 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.031242 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0298881 |
| RNF24 | ring finger protein 24 | -0.0282749 |
| FTL | ferritin, light polypeptide | -0.0248627 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0223216 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0216221 |
| CLINT1 | clathrin interactor 1 | -0.0191921 |
| SNX9 | sorting nexin 9 | -0.0165543 |
| ZNF292 | zinc finger protein 292 | -0.0164945 |
| SEPTIN7 | septin 7 | -0.0132461 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0128631 |
| FMNL2 | formin-like 2 | -0.00955556 |
| TCERG1 | transcription elongation regulator 1 | -0.00901062 |
| NBEAL1 | neurobeachin-like 1 | -0.00787285 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.00242588 |
