| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0511334 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0465552 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0457499 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0415246 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.032632 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0323844 |
| H1-0 | H1.0 linker histone | 0.0279609 |
| TENM2 | teneurin transmembrane protein 2 | 0.0278899 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0275722 |
| TRIM2 | tripartite motif containing 2 | 0.0252187 |
| SHROOM3 | shroom family member 3 | 0.0249847 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0247907 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0243324 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0243258 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0236403 |
| HDAC9 | histone deacetylase 9 | 0.0233664 |
| NRXN1 | neurexin 1 | 0.0232362 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0226591 |
| CDC73 | cell division cycle 73 | 0.0225428 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0219011 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0217805 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0214716 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0203985 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.019721 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0193582 |
| PRKD1 | protein kinase D1 | 0.0192538 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.019165 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0190922 |
| ATG5 | autophagy related 5 | 0.0190346 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189652 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0184916 |
| RHOH | ras homolog family member H | 0.0184676 |
| KLHDC10 | kelch domain containing 10 | 0.0180818 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.017966 |
| GRM1 | glutamate receptor, metabotropic 1 | 0.0179555 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0178292 |
| RPL4 | ribosomal protein L4 | 0.0176699 |
| WWC2 | WW and C2 domain containing 2 | 0.0169262 |
| DST | dystonin | 0.0168372 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0166013 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0165624 |
| PDS5B | PDS5 cohesin associated factor B | 0.016489 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0164775 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0164082 |
| TLK2 | tousled-like kinase 2 | 0.016256 |
| RPL21 | ribosomal protein L21 | 0.0161866 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0158932 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0158924 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0157535 |
| PDGFC | platelet derived growth factor C | 0.0155346 |
| WDR75 | WD repeat domain 75 | 0.0154394 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0153088 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0152706 |
| CERT1 | ceramide transporter 1 | 0.0150286 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0149521 |
| CPA6 | carboxypeptidase A6 | 0.0146762 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0146703 |
| ZFR | zinc finger RNA binding protein | 0.0146453 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0145985 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0142907 |
| RASAL2 | RAS protein activator like 2 | 0.0141897 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0141603 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0141336 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0140172 |
| NUMB | numb homolog (Drosophila) | 0.0139411 |
| FRYL | FRY-like | 0.0138234 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0138132 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0137898 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.0137664 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0137476 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0137366 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0137139 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0137113 |
| ZNF217 | zinc finger protein 217 | 0.0136917 |
| GPC3 | glypican 3 | 0.0136736 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0136014 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0135846 |
| ZNF655 | zinc finger protein 655 | 0.013504 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0134631 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0134268 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0133786 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0133445 |
| MEIS2 | Meis homeobox 2 | 0.0132141 |
| RINT1 | RAD50 interactor 1 | 0.0129903 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0129305 |
| USP25 | ubiquitin specific peptidase 25 | 0.0128892 |
| ANXA5 | annexin A5 | 0.0128639 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0128179 |
| DMXL1 | Dmx-like 1 | 0.0127938 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0127304 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0126229 |
| THOC1 | THO complex 1 | 0.0125704 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0123833 |
| PDS5A | PDS5 cohesin associated factor A | 0.0123008 |
| RYBP | RING1 and YY1 binding protein | 0.0122316 |
| FBXO33 | F-box protein 33 | 0.0121931 |
| SIRT1 | sirtuin 1 | 0.0121406 |
| DYM | dymeclin | 0.0120906 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0120201 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0120091 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.217194 |
| TMSB10 | thymosin beta 10 | -0.183105 |
| PTMA | prothymosin, alpha | -0.161823 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.122914 |
| RPS27A | ribosomal protein S27a | -0.0988569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0876459 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0836288 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0771785 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0755564 |
| UBC | ubiquitin C | -0.0745197 |
| RPS16 | ribosomal protein S16 | -0.0740646 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0739277 |
| RPL23 | ribosomal protein L23 | -0.0718429 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0708317 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0693685 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0677994 |
| ITGAV | integrin, alpha V | -0.0672012 |
| RPS8 | ribosomal protein S8 | -0.0669624 |
| COL3A1 | collagen, type III, alpha 1 | -0.0613034 |
| POTEF | POTE ankyrin domain family, member F | -0.0611724 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.058709 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0585695 |
| THBS1 | thrombospondin 1 | -0.0581164 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.057793 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0574655 |
| RPLP1 | ribosomal protein, large, P1 | -0.0574474 |
| COL5A2 | collagen, type V, alpha 2 | -0.0545802 |
| ACTG1 | actin gamma 1 | -0.05458 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.054425 |
| CALR | calreticulin | -0.0539303 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0536006 |
| RPL5 | ribosomal protein L5 | -0.0535601 |
| PCBP2 | poly(rC) binding protein 2 | -0.0526023 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0519278 |
| RPL35A | ribosomal protein L35a | -0.0513642 |
| B2M | beta-2-microglobulin | -0.0483683 |
| ENO1 | enolase 1, (alpha) | -0.0478616 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0469736 |
| RPL31 | ribosomal protein L31 | -0.0469231 |
| S100A10 | S100 calcium binding protein A10 | -0.0455982 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.045386 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0451512 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.044744 |
| RPS12 | ribosomal protein S12 | -0.0442761 |
| APP | amyloid beta (A4) precursor protein | -0.0442015 |
| RPS6 | ribosomal protein S6 | -0.0440198 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0431897 |
| AHNAK | AHNAK nucleoprotein | -0.0410593 |
| MKI67 | marker of proliferation Ki-67 | -0.0399003 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0397002 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0395289 |
| RPS25 | ribosomal protein S25 | -0.0386711 |
| COL1A2 | collagen, type I, alpha 2 | -0.0385361 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0384597 |
| EMP1 | epithelial membrane protein 1 | -0.0378979 |
| CANX | calnexin | -0.037281 |
| RPL37 | ribosomal protein L37 | -0.0372479 |
| SET | SET nuclear proto-oncogene | -0.0371934 |
| RPL37A | ribosomal protein L37a | -0.0359462 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0356858 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0355107 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0349062 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0345884 |
| RPL26 | ribosomal protein L26 | -0.0340385 |
| RPS13 | ribosomal protein S13 | -0.0339822 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0337626 |
| RPS3 | ribosomal protein S3 | -0.0336769 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0334768 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0332679 |
| LDHA | lactate dehydrogenase A | -0.0330388 |
| CALU | calumenin | -0.0326099 |
| RPL12 | ribosomal protein L12 | -0.0325017 |
| HMGB2 | high mobility group box 2 | -0.0318635 |
| RPS24 | ribosomal protein S24 | -0.0315404 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0310622 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0307104 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0305588 |
| RPL36A | ribosomal protein L36a | -0.0304555 |
| APOE | apolipoprotein E | -0.0302294 |
| RPL19 | ribosomal protein L19 | -0.0297544 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0296306 |
| RPLP2 | ribosomal protein, large, P2 | -0.029416 |
| RPL32 | ribosomal protein L32 | -0.0293913 |
| RPL30 | ribosomal protein L30 | -0.0292442 |
| PHIP | pleckstrin homology domain interacting protein | -0.0290861 |
| SEPTIN7 | septin 7 | -0.029007 |
| RBM25 | RNA binding motif protein 25 | -0.0286831 |
| ACTN4 | actinin, alpha 4 | -0.0285767 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0281047 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0280846 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0278244 |
| RPS19 | ribosomal protein S19 | -0.0277366 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0274671 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0269562 |
| ANXA2 | annexin A2 | -0.026878 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.026869 |
| PKM | pyruvate kinase, muscle | -0.0268605 |
| RPS27 | ribosomal protein S27 | -0.026744 |
| PGK1 | phosphoglycerate kinase 1 | -0.026683 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0266344 |
