| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO6 | myosin VI | 0.145675 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.12006 |
| FNDC3B | fibronectin type III domain containing 3B | 0.110685 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.108619 |
| TSC22D2 | TSC22 domain family, member 2 | 0.105407 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0994894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.08347 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0733835 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0712605 |
| FMNL2 | formin-like 2 | 0.0703686 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.069388 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0686009 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0681891 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0678208 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0675558 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0656544 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0628941 |
| PRRC2C | proline-rich coiled-coil 2C | 0.062149 |
| DSG2 | desmoglein 2 | 0.0619099 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0597263 |
| SLMAP | sarcolemma associated protein | 0.0564103 |
| RPL21 | ribosomal protein L21 | 0.056147 |
| LAMB3 | laminin, beta 3 | 0.0551347 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0548289 |
| PTK2 | protein tyrosine kinase 2 | 0.0543297 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0541234 |
| NCKAP1 | NCK-associated protein 1 | 0.0530566 |
| JMJD1C | jumonji domain containing 1C | 0.0523993 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0522185 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0520413 |
| TFG | TRK-fused gene | 0.0520347 |
| MEF2A | myocyte enhancer factor 2A | 0.0510789 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0507423 |
| GOLGA4 | golgin A4 | 0.050134 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0492898 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.049241 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0490564 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0485047 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0482043 |
| ZNF292 | zinc finger protein 292 | 0.047906 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0478391 |
| RNF145 | ring finger protein 145 | 0.0477189 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0474842 |
| BBX | bobby sox homolog (Drosophila) | 0.0466839 |
| RIOK3 | RIO kinase 3 | 0.0459214 |
| NAV2 | neuron navigator 2 | 0.0454036 |
| PDE8A | phosphodiesterase 8A | 0.0453124 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0451382 |
| RCOR1 | REST corepressor 1 | 0.0444017 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0443434 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0438962 |
| TMF1 | TATA element modulatory factor 1 | 0.0438451 |
| ZNF148 | zinc finger protein 148 | 0.0436989 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0436213 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0427928 |
| BRD4 | bromodomain containing 4 | 0.0425472 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0422047 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0420974 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0415598 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0412999 |
| YAP1 | Yes-associated protein 1 | 0.0407789 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.040762 |
| SETD5 | SET domain containing 5 | 0.0402435 |
| OGA | O-GlcNAcase | 0.0401986 |
| G0S2 | G0/G1 switch 2 | 0.0394879 |
| RASA2 | RAS p21 protein activator 2 | 0.0394481 |
| PARD3 | par-3 family cell polarity regulator | 0.039393 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.038802 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0387778 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0387569 |
| ATP13A3 | ATPase type 13A3 | 0.0384262 |
| RPS3 | ribosomal protein S3 | 0.0382574 |
| PDS5B | PDS5 cohesin associated factor B | 0.0382288 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0380882 |
| CCNY | cyclin Y | 0.0379903 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0379368 |
| MYO5B | myosin VB | 0.0379122 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0378688 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.037758 |
| TPM3 | tropomyosin 3 | 0.0374503 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0373974 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.037088 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0370866 |
| MED13L | mediator complex subunit 13-like | 0.0362383 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.036189 |
| DIAPH1 | diaphanous-related formin 1 | 0.0359358 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0357848 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0357079 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0354924 |
| VEGFA | vascular endothelial growth factor A | 0.0351421 |
| LMO7 | LIM domain 7 | 0.0349737 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0349252 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0349151 |
| FNIP1 | folliculin interacting protein 1 | 0.0348087 |
| FN1 | fibronectin 1 | 0.0338761 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0337093 |
| AFDN | afadin, adherens junction formation factor | 0.0336048 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0334894 |
| FLNB | filamin B, beta | 0.0334638 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0329097 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115031 |
| RPL35A | ribosomal protein L35a | -0.0915584 |
| EGR1 | early growth response 1 | -0.0766316 |
| HLA-C | major histocompatibility complex, class I, C | -0.0758888 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0739031 |
| PLAT | plasminogen activator, tissue | -0.0648123 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0627748 |
| RNF213 | ring finger protein 213 | -0.0573373 |
| NCOA7 | nuclear receptor coactivator 7 | -0.054759 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0537463 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0537364 |
| MUC4 | mucin 4, cell surface associated | -0.0523149 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.052297 |
| PLSCR1 | phospholipid scramblase 1 | -0.0514655 |
| HLA-B | major histocompatibility complex, class I, B | -0.0494095 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0490676 |
| TPM4 | tropomyosin 4 | -0.0490247 |
| RPL23 | ribosomal protein L23 | -0.0476344 |
| KRT19 | keratin 19, type I | -0.0474231 |
| THBS1 | thrombospondin 1 | -0.0469025 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0455442 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0453227 |
| RPLP1 | ribosomal protein, large, P1 | -0.042971 |
| EFNA5 | ephrin-A5 | -0.0423142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.041978 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0398817 |
| RPS24 | ribosomal protein S24 | -0.0397236 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.038985 |
| RPL34 | ribosomal protein L34 | -0.0358957 |
| OSMR | oncostatin M receptor | -0.0355873 |
| MUC16 | mucin 16, cell surface associated | -0.0334372 |
| CANX | calnexin | -0.0332185 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0330917 |
| EZR | ezrin | -0.0330326 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0325594 |
| ARF1 | ADP-ribosylation factor 1 | -0.0323461 |
| AHNAK | AHNAK nucleoprotein | -0.0323145 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0323111 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.030006 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0289875 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0282905 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0282103 |
| TXNRD1 | thioredoxin reductase 1 | -0.027911 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0274238 |
| TMSB10 | thymosin beta 10 | -0.0273014 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0272964 |
| ITGB4 | integrin, beta 4 | -0.0269311 |
| ANXA2 | annexin A2 | -0.0267174 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0266323 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.025651 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.0256356 |
| DOCK1 | dedicator of cytokinesis 1 | -0.025292 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0248403 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0247898 |
| IFI44 | interferon-induced protein 44 | -0.0247583 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0246844 |
| TUBB | tubulin, beta class I | -0.02468 |
| SDC4 | syndecan 4 | -0.0244031 |
| RPS20 | ribosomal protein S20 | -0.0242474 |
| TUBB4B | tubulin, beta 4B class IVb | -0.024246 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0241783 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0241236 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0236462 |
| ACTG1 | actin gamma 1 | -0.0235719 |
| DIAPH3 | diaphanous-related formin 3 | -0.0228386 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0226524 |
| ETV6 | ets variant 6 | -0.0226227 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0225416 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0224962 |
| RPS28 | ribosomal protein S28 | -0.0223537 |
| TGM2 | transglutaminase 2 | -0.022176 |
| S100A6 | S100 calcium binding protein A6 | -0.0219519 |
| KLF6 | Kruppel-like factor 6 | -0.0218532 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0218177 |
| EGFR | epidermal growth factor receptor | -0.0218145 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0214167 |
| RPS19 | ribosomal protein S19 | -0.0214075 |
| HMGA1 | high mobility group AT-hook 1 | -0.0213931 |
| KIF5B | kinesin family member 5B | -0.0213287 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0212832 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0212403 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0212281 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0212064 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0211886 |
| TC2N | tandem C2 domains, nuclear | -0.0211492 |
| RRBP1 | ribosome binding protein 1 | -0.0210457 |
| RPS5 | ribosomal protein S5 | -0.0209878 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0208507 |
| RPL38 | ribosomal protein L38 | -0.0207722 |
| VCL | vinculin | -0.0205902 |
| JUN | jun proto-oncogene | -0.0204271 |
| TAPBP | TAP binding protein (tapasin) | -0.0202232 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0197716 |
| CAVIN1 | caveolae associated protein 1 | -0.0196192 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0195744 |
| RTN3 | reticulon 3 | -0.0195578 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0194683 |
| WDR1 | WD repeat domain 1 | -0.0192383 |
| PLEC | plectin | -0.0190994 |
| C3 | complement component 3 | -0.0190188 |
