| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | 0.15795 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0888033 |
| ZNF292 | zinc finger protein 292 | 0.0865687 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0859598 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0837533 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.081937 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0810026 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0756487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0703295 |
| SBF2 | SET binding factor 2 | 0.0675995 |
| LAMB3 | laminin, beta 3 | 0.0675953 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0670873 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0656249 |
| FMNL2 | formin-like 2 | 0.0640546 |
| FLNB | filamin B, beta | 0.0640059 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0637066 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0624405 |
| RPL4 | ribosomal protein L4 | 0.0621254 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0612729 |
| PARD3 | par-3 family cell polarity regulator | 0.0597704 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0572256 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.054721 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0535425 |
| FHIT | fragile histidine triad | 0.0534813 |
| TTR | transthyretin | 0.0532949 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0507919 |
| CALD1 | caldesmon 1 | 0.0503674 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0498523 |
| BNC2 | basonuclin 2 | 0.0495279 |
| EXOC4 | exocyst complex component 4 | 0.0492943 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0481939 |
| RAD51B | RAD51 paralog B | 0.0480729 |
| USP3 | ubiquitin specific peptidase 3 | 0.0479326 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0468968 |
| FRMD4A | FERM domain containing 4A | 0.0463966 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0459648 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0453634 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0446563 |
| SETD5 | SET domain containing 5 | 0.0443392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0426983 |
| RASA2 | RAS p21 protein activator 2 | 0.0420278 |
| COG5 | component of oligomeric golgi complex 5 | 0.0416923 |
| PTK2 | protein tyrosine kinase 2 | 0.0416698 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0404402 |
| APP | amyloid beta (A4) precursor protein | 0.0398131 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0397236 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0396736 |
| DENND1A | DENN/MADD domain containing 1A | 0.0377464 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0368068 |
| CALR | calreticulin | 0.0367359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.036654 |
| ATP13A3 | ATPase type 13A3 | 0.0365937 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0363817 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0360347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0359772 |
| CD2AP | CD2-associated protein | 0.0358165 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0357044 |
| PGK1 | phosphoglycerate kinase 1 | 0.0354157 |
| POU2F1 | POU class 2 homeobox 1 | 0.0348935 |
| SRPK2 | SRSF protein kinase 2 | 0.0346389 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0345204 |
| ANO6 | anoctamin 6 | 0.0340484 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0337638 |
| DGKI | diacylglycerol kinase, iota | 0.0335942 |
| NF1 | neurofibromin 1 | 0.0332207 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0328738 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0327475 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0322751 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0319606 |
| TPD52 | tumor protein D52 | 0.0318947 |
| CORO1C | coronin, actin binding protein, 1C | 0.0315058 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0314088 |
| FOXO3 | forkhead box O3 | 0.0311621 |
| SMYD3 | SET and MYND domain containing 3 | 0.0310166 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0305406 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0302206 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0301996 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0301661 |
| NUP58 | nucleoporin 58 | 0.0301035 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0300706 |
| FNIP1 | folliculin interacting protein 1 | 0.0300475 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0299424 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0299257 |
| RPL3 | ribosomal protein L3 | 0.0298832 |
| OGA | O-GlcNAcase | 0.0295433 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0295016 |
| WDR43 | WD repeat domain 43 | 0.0294544 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.029301 |
| VCL | vinculin | 0.02904 |
| ECT2 | epithelial cell transforming 2 | 0.0290063 |
| CDC73 | cell division cycle 73 | 0.0286951 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0286082 |
| LDHA | lactate dehydrogenase A | 0.0286041 |
| XPO1 | exportin 1 | 0.0285803 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0285272 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283287 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0281655 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0281092 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0280722 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0280106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.140519 |
| MT2A | metallothionein 2A | -0.0936382 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0703828 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0670821 |
| POTEF | POTE ankyrin domain family, member F | -0.0589224 |
| RPS6 | ribosomal protein S6 | -0.0568144 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0505621 |
| RPS2 | ribosomal protein S2 | -0.0479053 |
| RPL35A | ribosomal protein L35a | -0.0469206 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0402549 |
| RPL9 | ribosomal protein L9 | -0.0401895 |
| RPL7 | ribosomal protein L7 | -0.0385279 |
| TXNRD1 | thioredoxin reductase 1 | -0.0384951 |
| RPL23 | ribosomal protein L23 | -0.0378607 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0378546 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0351493 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0347877 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0338333 |
| SGMS2 | sphingomyelin synthase 2 | -0.0330686 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.032816 |
| EGR1 | early growth response 1 | -0.0321359 |
| RECQL | RecQ helicase-like | -0.0302499 |
| NABP1 | nucleic acid binding protein 1 | -0.0299524 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0298022 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0290519 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0289187 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0284293 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0279713 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0279505 |
| MCL1 | myeloid cell leukemia 1 | -0.0273972 |
| RPL38 | ribosomal protein L38 | -0.0266677 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0263026 |
| RPL26 | ribosomal protein L26 | -0.0262415 |
| SP100 | SP100 nuclear antigen | -0.0257362 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0257073 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0256566 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.025501 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253401 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0250829 |
| EEA1 | early endosome antigen 1 | -0.0250201 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.024884 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0245867 |
| RPS20 | ribosomal protein S20 | -0.0240712 |
| DENND4A | DENN/MADD domain containing 4A | -0.0233564 |
| RPL34 | ribosomal protein L34 | -0.0232517 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0226155 |
| MYO9B | myosin IXB | -0.0223582 |
| RPL36 | ribosomal protein L36 | -0.0223529 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0222963 |
| PTMA | prothymosin, alpha | -0.0220828 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | -0.0218113 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.0218024 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0216209 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0211503 |
| RBM25 | RNA binding motif protein 25 | -0.0210528 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0209493 |
| ZNF706 | zinc finger protein 706 | -0.0207204 |
| TUT7 | terminal uridylyl transferase 7 | -0.0204824 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0204045 |
| S100A10 | S100 calcium binding protein A10 | -0.0201099 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0201022 |
| RPS27 | ribosomal protein S27 | -0.0196557 |
| ERBIN | erbb2 interacting protein | -0.0196172 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0195086 |
| JUN | jun proto-oncogene | -0.0194455 |
| RRBP1 | ribosome binding protein 1 | -0.0189945 |
| S100A9 | S100 calcium binding protein A9 | -0.0189877 |
| EFNB2 | ephrin-B2 | -0.018879 |
| RPL32 | ribosomal protein L32 | -0.0188343 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0184703 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0184141 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0182166 |
| UPP1 | uridine phosphorylase 1 | -0.0182094 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0181908 |
| CENPF | centromere protein F, 350/400kDa | -0.0181297 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0180202 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0178171 |
| RPS29 | ribosomal protein S29 | -0.0175992 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0175429 |
| ATF4 | activating transcription factor 4 | -0.01751 |
| MYO9A | myosin IXA | -0.0174805 |
| CDCP1 | CUB domain containing protein 1 | -0.0174371 |
| GPATCH2L | G patch domain containing 2-like | -0.0171834 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0171693 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0171445 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0170595 |
| HLA-C | major histocompatibility complex, class I, C | -0.0168194 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0167576 |
| RPL12 | ribosomal protein L12 | -0.0165406 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0165244 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0164651 |
| RPL8 | ribosomal protein L8 | -0.0164019 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0163243 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0162939 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0161887 |
| TPX2 | TPX2, microtubule-associated | -0.0161345 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0160706 |
| RPS24 | ribosomal protein S24 | -0.0159169 |
| SKI | SKI proto-oncogene | -0.0158691 |
| AHI1 | Abelson helper integration site 1 | -0.0157928 |
