| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.151169 |
| ZNF292 | zinc finger protein 292 | 0.122979 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11642 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.113168 |
| GOLGA4 | golgin A4 | 0.0990187 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0906242 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0808401 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0777411 |
| QKI | QKI, KH domain containing, RNA binding | 0.0681856 |
| TXNIP | thioredoxin interacting protein | 0.059348 |
| TFG | TRK-fused gene | 0.0544831 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0544623 |
| RBM39 | RNA binding motif protein 39 | 0.054208 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0528465 |
| RPL13A | ribosomal protein L13a | 0.0523937 |
| RNF145 | ring finger protein 145 | 0.049786 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0482592 |
| CCNL1 | cyclin L1 | 0.0479814 |
| RPS3 | ribosomal protein S3 | 0.0460926 |
| PFN1 | profilin 1 | 0.0457344 |
| RPS19 | ribosomal protein S19 | 0.0452264 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0450744 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0440116 |
| ECT2 | epithelial cell transforming 2 | 0.0439913 |
| RPL21 | ribosomal protein L21 | 0.0435389 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0433552 |
| DSTN | destrin (actin depolymerizing factor) | 0.0432625 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0422821 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0422408 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.042137 |
| RPL3 | ribosomal protein L3 | 0.0410807 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0404836 |
| MT2A | metallothionein 2A | 0.0394255 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390479 |
| RPL4 | ribosomal protein L4 | 0.0388141 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0385039 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0384758 |
| NUP58 | nucleoporin 58 | 0.0378991 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0378962 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0376873 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0373056 |
| NBAS | neuroblastoma amplified sequence | 0.036348 |
| RPL19 | ribosomal protein L19 | 0.0359015 |
| JMJD1C | jumonji domain containing 1C | 0.0356698 |
| CDC73 | cell division cycle 73 | 0.0354817 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0354787 |
| SLMAP | sarcolemma associated protein | 0.0349217 |
| COG5 | component of oligomeric golgi complex 5 | 0.0344892 |
| FTL | ferritin, light polypeptide | 0.0344455 |
| RPLP0 | ribosomal protein, large, P0 | 0.0342172 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0340725 |
| MORF4L2 | mortality factor 4 like 2 | 0.0340086 |
| HELZ | helicase with zinc finger | 0.0340027 |
| SETD5 | SET domain containing 5 | 0.033786 |
| ATOSA | atos homolog A | 0.0334765 |
| PGK1 | phosphoglycerate kinase 1 | 0.0325591 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0322346 |
| COPA | coatomer protein complex, subunit alpha | 0.0318254 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0315162 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.031459 |
| PTK2 | protein tyrosine kinase 2 | 0.031084 |
| SRP54 | signal recognition particle 54kDa | 0.0310602 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0308876 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0308608 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0304795 |
| DENND4A | DENN/MADD domain containing 4A | 0.0304612 |
| RPS29 | ribosomal protein S29 | 0.0301604 |
| RPL27A | ribosomal protein L27a | 0.0299123 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0297611 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0297303 |
| RTN4 | reticulon 4 | 0.0296054 |
| RPLP2 | ribosomal protein, large, P2 | 0.0295949 |
| RPS8 | ribosomal protein S8 | 0.0291323 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0289357 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.028704 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0286516 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0284151 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0283744 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0283531 |
| RPS2 | ribosomal protein S2 | 0.0282805 |
| USP3 | ubiquitin specific peptidase 3 | 0.0281448 |
| RPL7A | ribosomal protein L7a | 0.0280783 |
| RPL32 | ribosomal protein L32 | 0.0278506 |
| RBM25 | RNA binding motif protein 25 | 0.0274028 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0272109 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0270444 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0269847 |
| SUCO | SUN domain containing ossification factor | 0.0268029 |
| TMEM41B | transmembrane protein 41B | 0.0265424 |
| B2M | beta-2-microglobulin | 0.0264459 |
| YBX1 | Y box binding protein 1 | 0.0263434 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0262315 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0262076 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0260963 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0259974 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.025904 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0258436 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.025768 |
| OGA | O-GlcNAcase | 0.0257526 |
| RPL11 | ribosomal protein L11 | 0.0257159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.249539 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.240175 |
| PKM | pyruvate kinase, muscle | -0.129905 |
| BMP10 | bone morphogenetic protein 10 | -0.127367 |
| VCL | vinculin | -0.111592 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.103394 |
| EGFR | epidermal growth factor receptor | -0.0896175 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0893853 |
| FOXP1 | forkhead box P1 | -0.0841385 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0773704 |
| UBC | ubiquitin C | -0.0736949 |
| NBEA | neurobeachin | -0.0702213 |
| GLI3 | GLI family zinc finger 3 | -0.0677091 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0658208 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0598384 |
| GLI2 | GLI family zinc finger 2 | -0.0583779 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.058165 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0552382 |
| CCND1 | cyclin D1 | -0.0543411 |
| FLNB | filamin B, beta | -0.0535578 |
| TXNRD1 | thioredoxin reductase 1 | -0.0534104 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0526075 |
| GSE1 | Gse1 coiled-coil protein | -0.0453798 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0418028 |
| MYO5C | myosin VC | -0.0414946 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0405049 |
| SLC38A2 | solute carrier family 38, member 2 | -0.040246 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0392116 |
| PYGB | phosphorylase, glycogen; brain | -0.0391113 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.037994 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0376719 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.03721 |
| EXOC6B | exocyst complex component 6B | -0.0371127 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0366698 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0360165 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0352763 |
| ATP9B | ATPase, class II, type 9B | -0.034823 |
| PTMA | prothymosin, alpha | -0.0348147 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.034652 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0341461 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0333173 |
| RPL23 | ribosomal protein L23 | -0.0333034 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0326682 |
| ENO1 | enolase 1, (alpha) | -0.0325551 |
| RPS27A | ribosomal protein S27a | -0.0321777 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0320725 |
| BPTF | bromodomain PHD finger transcription factor | -0.0316697 |
| ZNF438 | zinc finger protein 438 | -0.0309014 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0300327 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0299152 |
| AMOTL2 | angiomotin like 2 | -0.0298611 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0296992 |
| CUX1 | cut-like homeobox 1 | -0.029672 |
| POTEF | POTE ankyrin domain family, member F | -0.029579 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0295191 |
| S100A4 | S100 calcium binding protein A4 | -0.0279667 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0278099 |
| EZR | ezrin | -0.0274754 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0272174 |
| SMYD3 | SET and MYND domain containing 3 | -0.0271357 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0271268 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267738 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0265058 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0262903 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0258306 |
| RPL35A | ribosomal protein L35a | -0.0258298 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0256855 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0255917 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0253965 |
| SP100 | SP100 nuclear antigen | -0.0253273 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0250385 |
| FUS | FUS RNA binding protein | -0.0245067 |
| PDE7B | phosphodiesterase 7B | -0.0243909 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0243143 |
| R3HDM2 | R3H domain containing 2 | -0.0242756 |
| ONECUT2 | one cut homeobox 2 | -0.0242447 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0241868 |
| AEBP2 | AE binding protein 2 | -0.0241519 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0240294 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.023874 |
| APP | amyloid beta (A4) precursor protein | -0.0238398 |
| COMMD10 | COMM domain containing 10 | -0.0237584 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0234455 |
| GPATCH2L | G patch domain containing 2-like | -0.0234193 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.023351 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0229621 |
| PRELID2 | PRELI domain containing 2 | -0.0228366 |
| ZNF608 | zinc finger protein 608 | -0.022589 |
| PCBP2 | poly(rC) binding protein 2 | -0.0225561 |
| LOXL3 | lysyl oxidase-like 3 | -0.0225494 |
| MACROD2 | MACRO domain containing 2 | -0.0223361 |
| SPIDR | scaffolding protein involved in DNA repair | -0.022212 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0221019 |
| DIAPH2 | diaphanous-related formin 2 | -0.0218114 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0218025 |
| DIAPH3 | diaphanous-related formin 3 | -0.0218022 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0216492 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0211426 |
| HDAC9 | histone deacetylase 9 | -0.0210501 |
| NAV2 | neuron navigator 2 | -0.0207511 |
