| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Imiquimod (maleate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.104823 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.10282 |
| KRT8 | keratin 8, type II | 0.102141 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0788147 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0775371 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0761371 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0750929 |
| MED13L | mediator complex subunit 13-like | 0.0744721 |
| NCKAP1 | NCK-associated protein 1 | 0.0703951 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0684568 |
| MATR3 | matrin 3 | 0.0656962 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0654762 |
| VMP1 | vacuole membrane protein 1 | 0.0641262 |
| RYBP | RING1 and YY1 binding protein | 0.0613922 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0601151 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0600695 |
| RHEB | Ras homolog enriched in brain | 0.0590353 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0584121 |
| H1-0 | H1.0 linker histone | 0.05785 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0567293 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0535433 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0528383 |
| AFDN | afadin, adherens junction formation factor | 0.0525614 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0518933 |
| USP3 | ubiquitin specific peptidase 3 | 0.051266 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.049578 |
| ZNF292 | zinc finger protein 292 | 0.0494649 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0488588 |
| TFG | TRK-fused gene | 0.0483499 |
| ACTN4 | actinin, alpha 4 | 0.0466014 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0456976 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0450177 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0447599 |
| MEF2A | myocyte enhancer factor 2A | 0.0446963 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0446569 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0444752 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0444489 |
| YAP1 | Yes-associated protein 1 | 0.0443261 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0440488 |
| JMJD1C | jumonji domain containing 1C | 0.043823 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.04379 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0432305 |
| OLA1 | Obg-like ATPase 1 | 0.0428796 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0428095 |
| UBQLN1 | ubiquilin 1 | 0.0424113 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0423997 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0422677 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0418772 |
| MTMR3 | myotubularin related protein 3 | 0.0418318 |
| CRY1 | cryptochrome circadian clock 1 | 0.0416116 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0416095 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0416089 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0415736 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0402815 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0400577 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0397806 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0395262 |
| RBM33 | RNA binding motif protein 33 | 0.0388344 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0385758 |
| WAC | WW domain containing adaptor with coiled-coil | 0.03815 |
| DIDO1 | death inducer-obliterator 1 | 0.0377787 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0374749 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0374738 |
| RTN4 | reticulon 4 | 0.0373636 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0371031 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0370557 |
| RBM39 | RNA binding motif protein 39 | 0.0369349 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0369113 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0367914 |
| AHNAK | AHNAK nucleoprotein | 0.0362517 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0357763 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0356368 |
| SUCO | SUN domain containing ossification factor | 0.0354598 |
| CDC73 | cell division cycle 73 | 0.0353519 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0350753 |
| ABI1 | abl-interactor 1 | 0.03476 |
| HSPA8 | heat shock 70kDa protein 8 | 0.03475 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0345087 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.034336 |
| NEK7 | NIMA-related kinase 7 | 0.0343145 |
| OGA | O-GlcNAcase | 0.0336035 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0334944 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0332339 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0332085 |
| MYO6 | myosin VI | 0.0331421 |
| MEMO1 | mediator of cell motility 1 | 0.032975 |
| PPME1 | protein phosphatase methylesterase 1 | 0.032969 |
| VCL | vinculin | 0.0328438 |
| SDC4 | syndecan 4 | 0.0327337 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0325653 |
| FRMD5 | FERM domain containing 5 | 0.0322069 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0321889 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.032119 |
| ECT2 | epithelial cell transforming 2 | 0.0318156 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0316585 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0312598 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0312102 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0310576 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0310061 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0305224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.136595 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.122091 |
| FTL | ferritin, light polypeptide | -0.119828 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.102566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0994171 |
| TMSB10 | thymosin beta 10 | -0.0938158 |
| NDRG1 | N-myc downstream regulated 1 | -0.0850528 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0848359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.078478 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.075127 |
| RPS6 | ribosomal protein S6 | -0.0728884 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0726475 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0664034 |
| PTMA | prothymosin, alpha | -0.065254 |
| EZR | ezrin | -0.0648868 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0624107 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.061952 |
| EGR1 | early growth response 1 | -0.0600225 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0562215 |
| LDHA | lactate dehydrogenase A | -0.0551763 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0545006 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0529227 |
| S100A6 | S100 calcium binding protein A6 | -0.0527622 |
| EHBP1 | EH domain binding protein 1 | -0.0477737 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0466018 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0458667 |
| RPL35A | ribosomal protein L35a | -0.0455725 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0450624 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0429258 |
| HLA-A | major histocompatibility complex, class I, A | -0.0422488 |
| B2M | beta-2-microglobulin | -0.0405472 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376992 |
| ITGB4 | integrin, beta 4 | -0.0370705 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0368499 |
| S100A9 | S100 calcium binding protein A9 | -0.036742 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0366532 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0365993 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.03463 |
| CUX1 | cut-like homeobox 1 | -0.0343173 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0342284 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0340017 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0337709 |
| DNM2 | dynamin 2 | -0.0333444 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0332393 |
| TPM4 | tropomyosin 4 | -0.0329735 |
| RPS19 | ribosomal protein S19 | -0.0324053 |
| HM13 | histocompatibility (minor) 13 | -0.0322523 |
| CLDN4 | claudin 4 | -0.0313794 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0312282 |
| OXSR1 | oxidative stress responsive 1 | -0.0311151 |
| PERP | PERP, TP53 apoptosis effector | -0.0309037 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0302765 |
| CXXC5 | CXXC finger protein 5 | -0.0302318 |
| BPTF | bromodomain PHD finger transcription factor | -0.0302073 |
| CADPS | Ca++-dependent secretion activator | -0.0300914 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0300764 |
| GOLGB1 | golgin B1 | -0.0299829 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0297119 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0294941 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0294925 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0289616 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0288774 |
| HMGA1 | high mobility group AT-hook 1 | -0.0286819 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284973 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0283363 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0278319 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0277142 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.027622 |
| NEBL | nebulette | -0.0274293 |
| NFIA | nuclear factor I/A | -0.0271674 |
| ATP9A | ATPase, class II, type 9A | -0.0269768 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0269238 |
| STC2 | stanniocalcin 2 | -0.0268167 |
| CTSD | cathepsin D | -0.026607 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265887 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0265804 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0263202 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0261949 |
| DACH1 | dachshund family transcription factor 1 | -0.0261762 |
| KRT19 | keratin 19, type I | -0.0261086 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0259595 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0258938 |
| KRT20 | keratin 20, type I | -0.025653 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256042 |
| PKM | pyruvate kinase, muscle | -0.0255674 |
| TMEM123 | transmembrane protein 123 | -0.0255617 |
| ANXA4 | annexin A4 | -0.025551 |
| FOSL1 | FOS-like antigen 1 | -0.025437 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0253022 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0250977 |
| RSF1 | remodeling and spacing factor 1 | -0.0250926 |
| ARF4 | ADP-ribosylation factor 4 | -0.025045 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.024887 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0246583 |
| ERBIN | erbb2 interacting protein | -0.0245131 |
| FNBP4 | formin binding protein 4 | -0.0244729 |
| JUN | jun proto-oncogene | -0.0238076 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0238048 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0236194 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0236181 |
