| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Imiquimod (maleate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Imiquimod (maleate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.187522 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.128701 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.113691 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.084985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0831725 |
| PARD3 | par-3 family cell polarity regulator | 0.0818086 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0790497 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0746806 |
| TSC22D2 | TSC22 domain family, member 2 | 0.07274 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0714896 |
| ZNF292 | zinc finger protein 292 | 0.0711498 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0706524 |
| RNF145 | ring finger protein 145 | 0.0667155 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.065064 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0638487 |
| COG5 | component of oligomeric golgi complex 5 | 0.0628369 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0622503 |
| SNX9 | sorting nexin 9 | 0.0621596 |
| MYO5B | myosin VB | 0.0602712 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0590052 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0584932 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0579955 |
| SBF2 | SET binding factor 2 | 0.0551109 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0544672 |
| EZR | ezrin | 0.0543135 |
| CENPF | centromere protein F, 350/400kDa | 0.053823 |
| IER3 | immediate early response 3 | 0.0523472 |
| RPL3 | ribosomal protein L3 | 0.0513831 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0512326 |
| NUP58 | nucleoporin 58 | 0.0503761 |
| ANLN | anillin, actin binding protein | 0.0502583 |
| BBX | bobby sox homolog (Drosophila) | 0.0502334 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0500957 |
| WDR43 | WD repeat domain 43 | 0.0493568 |
| RBM39 | RNA binding motif protein 39 | 0.0491797 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0487853 |
| NDRG1 | N-myc downstream regulated 1 | 0.0486605 |
| ECT2 | epithelial cell transforming 2 | 0.0482927 |
| RAB1A | RAB1A, member RAS oncogene family | 0.047917 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0472971 |
| NEK7 | NIMA-related kinase 7 | 0.0469806 |
| SLMAP | sarcolemma associated protein | 0.0465112 |
| RREB1 | ras responsive element binding protein 1 | 0.0458635 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0455494 |
| ANXA1 | annexin A1 | 0.0453126 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0450279 |
| USP3 | ubiquitin specific peptidase 3 | 0.0444514 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0438911 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0429425 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.042174 |
| MYO1B | myosin IB | 0.042063 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0417254 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0414463 |
| OXSR1 | oxidative stress responsive 1 | 0.0413978 |
| FMNL2 | formin-like 2 | 0.0413161 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0405388 |
| NCKAP1 | NCK-associated protein 1 | 0.0404113 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0403891 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0401459 |
| GOLGA4 | golgin A4 | 0.0387836 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0385404 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0384258 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0383657 |
| EREG | epiregulin | 0.0377949 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0375638 |
| FOSL1 | FOS-like antigen 1 | 0.0374141 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0373963 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0373028 |
| CDC73 | cell division cycle 73 | 0.0371267 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0368694 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.036703 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0365382 |
| ANXA2 | annexin A2 | 0.0364502 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036029 |
| TOP1 | topoisomerase (DNA) I | 0.0358477 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0354899 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0343314 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0341376 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0337467 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0334992 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0331971 |
| FBXO11 | F-box protein 11 | 0.033132 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0330186 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0328797 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.032235 |
| CCNY | cyclin Y | 0.0319083 |
| LDHA | lactate dehydrogenase A | 0.0318269 |
| TNPO1 | transportin 1 | 0.0317826 |
| YOD1 | YOD1 deubiquitinase | 0.031738 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0313477 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0309195 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0307677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0307347 |
| ANXA11 | annexin A11 | 0.0305506 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0304446 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303961 |
| ATP13A3 | ATPase type 13A3 | 0.0303914 |
| ENO1 | enolase 1, (alpha) | 0.0302684 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0301805 |
| WASF2 | WAS protein family, member 2 | 0.0298888 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.153166 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0967186 |
| EGR1 | early growth response 1 | -0.0946859 |
| HMGA2 | high mobility group AT-hook 2 | -0.0819417 |
| ATXN1 | ataxin 1 | -0.0764456 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.075617 |
| RPL35A | ribosomal protein L35a | -0.0665112 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0618733 |
| RPS24 | ribosomal protein S24 | -0.0594119 |
| VCL | vinculin | -0.0556044 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0522229 |
| RPL34 | ribosomal protein L34 | -0.0512478 |
| FHL2 | four and a half LIM domains 2 | -0.0502294 |
| LAMA4 | laminin, alpha 4 | -0.0495452 |
| RPL23 | ribosomal protein L23 | -0.0493417 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0459641 |
| RPLP2 | ribosomal protein, large, P2 | -0.0449908 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.042185 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0420407 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0418588 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.041722 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0406343 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.040416 |
| RPL31 | ribosomal protein L31 | -0.0397588 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0395214 |
| KLF6 | Kruppel-like factor 6 | -0.0388756 |
| CDK13 | cyclin-dependent kinase 13 | -0.0386789 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382455 |
| HMGA1 | high mobility group AT-hook 1 | -0.0376151 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0367925 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0361038 |
| RPL36A | ribosomal protein L36a | -0.0355579 |
| CTSB | cathepsin B | -0.0350987 |
| TMSB10 | thymosin beta 10 | -0.0343476 |
| MTAP | methylthioadenosine phosphorylase | -0.0342812 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0340479 |
| RPS8 | ribosomal protein S8 | -0.0336503 |
| RAB10 | RAB10, member RAS oncogene family | -0.0336371 |
| TNS3 | tensin 3 | -0.033472 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0324643 |
| RPL12 | ribosomal protein L12 | -0.0321383 |
| RPL36 | ribosomal protein L36 | -0.0319385 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0317442 |
| PHF14 | PHD finger protein 14 | -0.0317045 |
| RPL8 | ribosomal protein L8 | -0.0310176 |
| RPL9 | ribosomal protein L9 | -0.0309228 |
| SEPTIN9 | septin 9 | -0.030751 |
| EMP1 | epithelial membrane protein 1 | -0.0302748 |
| OXR1 | oxidation resistance 1 | -0.0291731 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0291183 |
| EXOC6B | exocyst complex component 6B | -0.0289361 |
| RPS29 | ribosomal protein S29 | -0.0283247 |
| RPL28 | ribosomal protein L28 | -0.0279131 |
| RPL26 | ribosomal protein L26 | -0.0276628 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0276274 |
| RPS15 | ribosomal protein S15 | -0.0273186 |
| HDAC4 | histone deacetylase 4 | -0.0267739 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0266711 |
| LMO7 | LIM domain 7 | -0.0263682 |
| EHBP1 | EH domain binding protein 1 | -0.0262156 |
| AREG | amphiregulin | -0.026207 |
| RPS6 | ribosomal protein S6 | -0.0260533 |
| RPS25 | ribosomal protein S25 | -0.026037 |
| KIAA1217 | KIAA1217 | -0.0259597 |
| RPS4X | ribosomal protein S4, X-linked | -0.0254649 |
| HM13 | histocompatibility (minor) 13 | -0.0254187 |
| PTMA | prothymosin, alpha | -0.0250587 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0250073 |
| GOLGB1 | golgin B1 | -0.0249504 |
| ARF1 | ADP-ribosylation factor 1 | -0.0247308 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.0244023 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0243162 |
| S100A9 | S100 calcium binding protein A9 | -0.0240257 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0240126 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0238748 |
| FNIP1 | folliculin interacting protein 1 | -0.0238727 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0238347 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0235946 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0235108 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0234843 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0231236 |
| FMN1 | formin 1 | -0.0230948 |
| DUSP4 | dual specificity phosphatase 4 | -0.0230034 |
| FOXN3 | forkhead box N3 | -0.0224346 |
| SPATA13 | spermatogenesis associated 13 | -0.0223683 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0223448 |
| SLC30A10 | solute carrier family 30, member 10 | -0.0221978 |
| MT1X | metallothionein 1X | -0.0219164 |
| R3HDM1 | R3H domain containing 1 | -0.0218679 |
| S100A10 | S100 calcium binding protein A10 | -0.0213762 |
| CEP350 | centrosomal protein 350kDa | -0.0213185 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0211463 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0210716 |
| SGMS2 | sphingomyelin synthase 2 | -0.0210552 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0206943 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0206104 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0204627 |
| RBM25 | RNA binding motif protein 25 | -0.0204499 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0203243 |
| ABR | active BCR-related | -0.0198237 |
