Immune Thrombocytopenic Purpura Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0398650
Similar Terms
Downloads & Tools

Genes

297 genes associated with the disease Immune Thrombocytopenic Purpura in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACP5 acid phosphatase 5, tartrate resistant
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTN1 actinin, alpha 1
ADA adenosine deaminase
ADAM10 ADAM metallopeptidase domain 10
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADRB3 adrenoceptor beta 3
AHCY adenosylhomocysteinase
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA1 annexin A1
APOH apolipoprotein H (beta-2-glycoprotein I)
AR androgen receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG7 autophagy related 7
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BID BH3 interacting domain death agonist
BMI1 BMI1 proto-oncogene, polycomb ring finger
C21ORF33 chromosome 21 open reading frame 33
CAMP cathelicidin antimicrobial peptide
CARD9 caspase recruitment domain family, member 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD19 CD19 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD68 CD68 molecule
CD69 CD69 molecule
CD70 CD70 molecule
CD72 CD72 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDCA5 cell division cycle associated 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CIITA class II, major histocompatibility complex, transactivator
CLEC1B C-type lectin domain family 1, member B
CNR2 cannabinoid receptor 2 (macrophage)
COMMD3-BMI1 COMMD3-BMI1 readthrough
COX1
COX2
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL9 cullin 9
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CXCR6 chemokine (C-X-C motif) receptor 6
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DLL1 delta-like 1 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB2 EPH receptor B2
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF2 fibroblast growth factor 2 (basic)
FKBP5 FK506 binding protein 5
FOXP3 forkhead box P3
GALC galactosylceramidase
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GFI1B growth factor independent 1B transcription repressor
GGCT gamma-glutamylcyclotransferase
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP5 glycoprotein V (platelet)
GP6 glycoprotein VI (platelet)
GP9 glycoprotein IX (platelet)
GRN granulin
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HES1 hes family bHLH transcription factor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HOXA5 homeobox A5
HOXB4 homeobox B4
HOXD13 homeobox D13
HPSE heparanase
HPSE2 heparanase 2 (inactive)
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGH immunoglobulin heavy locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL11 interleukin 11
IL12A interleukin 12A
IL16 interleukin 16
IL17A interleukin 17A
IL17D interleukin 17D
IL17F interleukin 17F
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL33 interleukin 33
IL37 interleukin 37
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL7R interleukin 7 receptor
IL9 interleukin 9
INSRR insulin receptor-related receptor
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
JAK2 Janus kinase 2
KDM6A lysine (K)-specific demethylase 6A
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KMT2D lysine (K)-specific methyltransferase 2D
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LEP leptin
LGALS9 lectin, galactoside-binding, soluble, 9
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724023 ES1 protein homolog, mitochondrial
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC105375355 uroplakin-3b
LTA lymphotoxin alpha
MALT1 MALT1 paracaspase
MAP6 microtubule-associated protein 6
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MBD4 methyl-CpG binding domain protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRC1 mannose receptor, C type 1
MRPL28 mitochondrial ribosomal protein L28
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSC musculin
MYDGF myeloid-derived growth factor
MYH9 myosin, heavy chain 9, non-muscle
NAP1L1 nucleosome assembly protein 1-like 1
NCAM1 neural cell adhesion molecule 1
NELL1 NEL-like 1 (chicken)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLRP3 NLR family, pyrin domain containing 3
NOTCH1 notch 1
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NXT1 nuclear transport factor 2-like export factor 1
OPTN optineurin
PDCD1 programmed cell death 1
PNP purine nucleoside phosphorylase
PRB2 proline-rich protein BstNI subfamily 2
PRKCD protein kinase C, delta
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFXANK regulatory factor X-associated ankyrin-containing protein
RFXAP regulatory factor X-associated protein
RHD Rh blood group, D antigen
RNF112 ring finger protein 112
RO60 Ro60, Y RNA binding protein
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
SCAMP1 secretory carrier membrane protein 1
SCAMP2 secretory carrier membrane protein 2
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC7A4 solute carrier family 7, member 4
SMAD7 SMAD family member 7
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STS steroid sulfatase (microsomal), isozyme S
SUB1 SUB1 homolog (S. cerevisiae)
SYK spleen tyrosine kinase
T T, brachyury homolog (mouse)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX21 T-box 21
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THPO thrombopoietin
TIMELESS timeless circadian clock
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53 tumor protein p53
TPO thyroid peroxidase
TPP2 tripeptidyl peptidase II
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIT1 tRNA isopentenyltransferase 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSHZ1 teashirt zinc finger homeobox 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VNN1 vanin 1
VWF von Willebrand factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa