Impetigo Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A pyoderma consisting of three forms of skin lesions having either a thick, adherent, recurrent, dirty yellow crust with an erythematous margin (common or superficial impetigo) or lessions which are superficial, thin-walled, and bullous as found in bullous impetigo. The lesions in bullous (staphylococcal) impetigo, which are always caused by S aureus, are superficial, thin-walled, and bullous. (Human Disease Ontology, DOID_8504)
Similar Terms
Downloads & Tools

Genes

183 genes co-occuring with the disease Impetigo in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MYOM2 myomesin 2 3.018
DSG1 desmoglein 1 2.843
EDNRB endothelin receptor type B 2.694
IL36RN interleukin 36 receptor antagonist 2.433
DSG3 desmoglein 3 2.32
EDNRA endothelin receptor type A 2.227
CAMP cathelicidin antimicrobial peptide 2.102
CARD14 caspase recruitment domain family, member 14 2.084
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.014
ERV3-1 endogenous retrovirus group 3, member 1 2.014
IL36R interleukin 36 receptor 1.978
ERVW-1 endogenous retrovirus group W, member 1 1.94
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.94
DST dystonin 1.926
COL17A1 collagen, type XVII, alpha 1 1.925
FN1 fibronectin 1 1.923
FLG filaggrin 1.922
FLG2 filaggrin family member 2 1.921
DSG4 desmoglein 4 1.911
CRP C-reactive protein, pentraxin-related 1.903
TNF tumor necrosis factor 1.888
SETBP1 SET binding protein 1 1.863
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.832
PLG plasminogen 1.811
CD4 CD4 molecule 1.799
IL17A interleukin 17A 1.799
IL1B interleukin 1, beta 1.797
DSC3 desmocollin 3 1.775
SPEG SPEG complex locus 1.765
IL6 interleukin 6 1.764
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.76
NUCB1 nucleobindin 1 1.749
IFNG interferon, gamma 1.746
PLK4 polo-like kinase 4 1.738
CXCL8 chemokine (C-X-C motif) ligand 8 1.733
ALB albumin 1.731
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.716
C3 complement component 3 1.714
IL1A interleukin 1, alpha 1.698
DEFB103A defensin, beta 103A 1.691
DSG2 desmoglein 2 1.683
GUK1 guanylate kinase 1 1.672
RNASE7 ribonuclease, RNase A family, 7 1.667
DSC1 desmocollin 1 1.658
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.658
DSP desmoplakin 1.631
DEFB4A defensin, beta 4A 1.623
IL22 interleukin 22 1.615
IL4 interleukin 4 1.613
IL31 interleukin 31 1.591
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.568
CD8A CD8a molecule 1.564
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.556
TLR2 toll-like receptor 2 1.553
IL10 interleukin 10 1.514
LTF lactotransferrin 1.509
ELN elastin 1.495
IL13 interleukin 13 1.492
AIF1L allograft inflammatory factor 1-like 1.482
SELENOO selenoprotein O 1.474
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 1.46
IL2 interleukin 2 1.45
CDSN corneodesmosin 1.443
C4B complement component 4B (Chido blood group) 1.408
DEFB1 defensin, beta 1 1.407
HTN3 histatin 3 1.392
IARS1 isoleucyl-tRNA synthetase 1 1.388
CSF3 colony stimulating factor 3 (granulocyte) 1.385
TPI1 triosephosphate isomerase 1 1.378
IL5 interleukin 5 1.375
MSRA methionine sulfoxide reductase A 1.368
HPR haptoglobin-related protein 1.365
BTK Bruton agammaglobulinemia tyrosine kinase 1.352
C4A complement component 4A (Rodgers blood group) 1.352
SPINK5 serine peptidase inhibitor, Kazal type 5 1.345
SELENOK selenoprotein K 1.343
MPO myeloperoxidase 1.338
POM121 POM121 transmembrane nucleoporin 1.323
PPL periplakin 1.312
LARS1 leucyl-tRNA synthetase 1 1.307
PRTN3 proteinase 3 1.306
DCD dermcidin 1.306
AZU1 azurocidin 1 1.296
TSLP thymic stromal lymphopoietin 1.292
CALCOCO2 calcium binding and coiled-coil domain 2 1.286
DOCK8 dedicator of cytokinesis 8 1.28
PKP3 plakophilin 3 1.275
FUT2 fucosyltransferase 2 (secretor status included) 1.274
GLS2 glutaminase 2 (liver, mitochondrial) 1.264
CTSG cathepsin G 1.261
SEC11C SEC11 homolog C (S. cerevisiae) 1.257
HOXD13 homeobox D13 1.254
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.248
MYD88 myeloid differentiation primary response 88 1.226
ELANE elastase, neutrophil expressed 1.226
EVPL envoplakin 1.212
IL17RA interleukin 17 receptor A 1.21
SEC11A SEC11 homolog A (S. cerevisiae) 1.208
HTN1 histatin 1 1.207
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.203
IL36G interleukin 36, gamma 1.202
TARS3 threonyl-tRNA synthetase 3 1.199
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.199
IL17F interleukin 17F 1.198
LARS2 leucyl-tRNA synthetase 2, mitochondrial 1.197
CFP complement factor properdin 1.197
KRT10 keratin 10, type I 1.196
IRAK4 interleukin-1 receptor-associated kinase 4 1.192
EPHA4 EPH receptor A4 1.186
EPHX2 epoxide hydrolase 2, cytoplasmic 1.175
TLR9 toll-like receptor 9 1.171
NOD2 nucleotide-binding oligomerization domain containing 2 1.17
PEPD peptidase D 1.17
DEFB4B defensin, beta 4B 1.168
KLK5 kallikrein-related peptidase 5 1.163
PKP1 plakophilin 1 1.156
PLEC plectin 1.154
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.149
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1.148
IL33 interleukin 33 1.147
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1.146
S100A7 S100 calcium binding protein A7 1.143
NBR1 neighbor of BRCA1 gene 1 1.139
TLR4 toll-like receptor 4 1.134
VTN vitronectin 1.134
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.129
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.123
TARS1 threonyl-tRNA synthetase 1 1.115
EXOC1 exocyst complex component 1 1.114
HTRA1 HtrA serine peptidase 1 1.109
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 1.107
G6PD glucose-6-phosphate dehydrogenase 1.106
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.104
CD19 CD19 molecule 1.102
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.1
CCDC6 coiled-coil domain containing 6 1.094
PKP2 plakophilin 2 1.092
CTRB2 chymotrypsinogen B2 1.089
SELENON selenoprotein N 1.088
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.087
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 1.087
GAP43 growth associated protein 43 1.084
CTRB1 chymotrypsinogen B1 1.083
IL1R1 interleukin 1 receptor, type I 1.082
DCLRE1C DNA cross-link repair 1C 1.08
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.076
CXCL2 chemokine (C-X-C motif) ligand 2 1.075
KNG1 kininogen 1 1.074
C5AR1 complement component 5a receptor 1 1.073
BRD3 bromodomain containing 3 1.069
DUSP5 dual specificity phosphatase 5 1.067
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.067
MSRB2 methionine sulfoxide reductase B2 1.067
FPR2 formyl peptide receptor 2 1.065
CD207 CD207 molecule, langerin 1.064
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 1.063
AGR3 anterior gradient 3 1.063
F2 coagulation factor II (thrombin) 1.062
FBXO3 F-box protein 3 1.057
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.056
KRT1 keratin 1, type II 1.054
IL18 interleukin 18 1.052
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.045
TCF15 transcription factor 15 (basic helix-loop-helix) 1.044
ACE angiotensin I converting enzyme 1.04
TYR tyrosinase 1.037
CYBA cytochrome b-245, alpha polypeptide 1.034
LYPD4 LY6/PLAUR domain containing 4 1.034
IL12RB1 interleukin 12 receptor, beta 1 1.033
TAC1 tachykinin, precursor 1 1.033
COL7A1 collagen, type VII, alpha 1 1.029
VWF von Willebrand factor 1.028
C1R complement component 1, r subcomponent 1.024
NCF1 neutrophil cytosolic factor 1 1.023
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.019
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.017
CXCR1 chemokine (C-X-C motif) receptor 1 1.014
CCL20 chemokine (C-C motif) ligand 20 1.012
BPI bactericidal/permeability-increasing protein 1.011
C1S complement component 1, s subcomponent 1.011
MBL2 mannose-binding lectin (protein C) 2, soluble 1.008
KANSL3 KAT8 regulatory NSL complex subunit 3 1.007
TMIE transmembrane inner ear 1.001