| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.175639 |
| B2M | beta-2-microglobulin | 0.139857 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116397 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.114852 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.103312 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.10145 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0911129 |
| COPA | coatomer protein complex, subunit alpha | 0.077674 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.065695 |
| CD109 | CD109 molecule | 0.063321 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0607595 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0575467 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0568374 |
| FNIP1 | folliculin interacting protein 1 | 0.0561477 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0543663 |
| PLAT | plasminogen activator, tissue | 0.0525479 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0512806 |
| OGA | O-GlcNAcase | 0.0495423 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0477909 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0426511 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0422795 |
| AUTS2 | autism susceptibility candidate 2 | 0.0416272 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.041098 |
| OPTN | optineurin | 0.0399213 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0398125 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0398013 |
| GOLGA4 | golgin A4 | 0.0394876 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0385727 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0376053 |
| HELZ | helicase with zinc finger | 0.03483 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0341739 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340382 |
| SUCO | SUN domain containing ossification factor | 0.0337669 |
| NAV2 | neuron navigator 2 | 0.0335695 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0329053 |
| LOX | lysyl oxidase | 0.0324876 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0322322 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.032126 |
| FMNL2 | formin-like 2 | 0.0320701 |
| MMP12 | matrix metallopeptidase 12 | 0.0320161 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0316456 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0314436 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0308664 |
| HIP1 | huntingtin interacting protein 1 | 0.0307971 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0307951 |
| HDAC9 | histone deacetylase 9 | 0.0306757 |
| MSN | moesin | 0.0301383 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0300859 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0296614 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0292212 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0291216 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0289671 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0286911 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0282157 |
| TAOK1 | TAO kinase 1 | 0.0280989 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0280096 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0279782 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0278915 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0277721 |
| APP | amyloid beta (A4) precursor protein | 0.0276867 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0274175 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.027385 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0273269 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0270896 |
| NGLY1 | N-glycanase 1 | 0.0270889 |
| DST | dystonin | 0.0268459 |
| SETD5 | SET domain containing 5 | 0.0266245 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0265768 |
| GOLGA2 | golgin A2 | 0.0262455 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0261692 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0261685 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0258702 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0257363 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0256268 |
| JMJD1C | jumonji domain containing 1C | 0.0253819 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0252284 |
| SLC22A23 | solute carrier family 22, member 23 | 0.025079 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0249337 |
| CCNY | cyclin Y | 0.0247613 |
| RAB18 | RAB18, member RAS oncogene family | 0.0247418 |
| ATP13A3 | ATPase type 13A3 | 0.0246267 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0245958 |
| RAI1 | retinoic acid induced 1 | 0.0243996 |
| TMSB4X | thymosin beta 4, X-linked | 0.0243968 |
| EZR | ezrin | 0.024361 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0243296 |
| DENND5A | DENN/MADD domain containing 5A | 0.0241609 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0240517 |
| CERT1 | ceramide transporter 1 | 0.0240223 |
| CYTH3 | cytohesin 3 | 0.0240006 |
| MSI2 | musashi RNA-binding protein 2 | 0.0238227 |
| PGK1 | phosphoglycerate kinase 1 | 0.0237285 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0237004 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.023562 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.023541 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0235167 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0235067 |
| FAM107B | family with sequence similarity 107, member B | 0.0234883 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0233308 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0233211 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.269435 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229186 |
| TMSB10 | thymosin beta 10 | -0.152163 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.140336 |
| MT2A | metallothionein 2A | -0.124661 |
| CD44 | CD44 molecule (Indian blood group) | -0.0978463 |
| AHNAK | AHNAK nucleoprotein | -0.0946034 |
| S100A10 | S100 calcium binding protein A10 | -0.0869032 |
| PODXL | podocalyxin-like | -0.0851825 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0704407 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0671419 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0653528 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0621827 |
| MAP1B | microtubule-associated protein 1B | -0.059356 |
| MX2 | MX dynamin-like GTPase 2 | -0.057735 |
| POTEF | POTE ankyrin domain family, member F | -0.0576169 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0527394 |
| NAV1 | neuron navigator 1 | -0.0524093 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0496761 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0493982 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0486424 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0485627 |
| MEIS2 | Meis homeobox 2 | -0.048481 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0477906 |
| CCND1 | cyclin D1 | -0.0477006 |
| RPL35A | ribosomal protein L35a | -0.0452112 |
| RNF213 | ring finger protein 213 | -0.0440979 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0438394 |
| RIGI | RNA sensor RIG-I | -0.0436474 |
| HLA-B | major histocompatibility complex, class I, B | -0.0435793 |
| HLA-C | major histocompatibility complex, class I, C | -0.0412545 |
| ANXA2 | annexin A2 | -0.0410576 |
| ACTG1 | actin gamma 1 | -0.0394805 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0394725 |
| RPLP1 | ribosomal protein, large, P1 | -0.0392644 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0389739 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0389506 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382382 |
| COL1A2 | collagen, type I, alpha 2 | -0.0381311 |
| GNAS | GNAS complex locus | -0.037647 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0375007 |
| CDK6 | cyclin-dependent kinase 6 | -0.0374821 |
| RPS24 | ribosomal protein S24 | -0.0370617 |
| S100A6 | S100 calcium binding protein A6 | -0.0370124 |
| PRSS23 | protease, serine, 23 | -0.0362762 |
| RPL28 | ribosomal protein L28 | -0.0359203 |
| LDHA | lactate dehydrogenase A | -0.0357154 |
| PXDN | peroxidasin | -0.0357095 |
| TUBB | tubulin, beta class I | -0.0356976 |
| FBN1 | fibrillin 1 | -0.0346758 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0346654 |
| PTMA | prothymosin, alpha | -0.0344762 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0342259 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337684 |
| ZNF217 | zinc finger protein 217 | -0.0334751 |
| UBC | ubiquitin C | -0.033373 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.033294 |
| RPL23 | ribosomal protein L23 | -0.0325802 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0320477 |
| TAGLN2 | transgelin 2 | -0.0318217 |
| ARF1 | ADP-ribosylation factor 1 | -0.0309718 |
| CAVIN1 | caveolae associated protein 1 | -0.0302147 |
| RPS6 | ribosomal protein S6 | -0.02928 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0290674 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0287379 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0286218 |
| NPR2 | natriuretic peptide receptor 2 | -0.0286205 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0284144 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0283795 |
| RPLP0 | ribosomal protein, large, P0 | -0.0282927 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0280711 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0277982 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0277771 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0276849 |
| HMGB1 | high mobility group box 1 | -0.0275267 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.027297 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0272512 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0270734 |
| H3-3B | H3.3 histone B | -0.0268326 |
| THBS2 | thrombospondin 2 | -0.0265082 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0261984 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0261093 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254689 |
| RPLP2 | ribosomal protein, large, P2 | -0.025356 |
| S100A4 | S100 calcium binding protein A4 | -0.0253235 |
| PFN1 | profilin 1 | -0.0252896 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0252568 |
| RRBP1 | ribosome binding protein 1 | -0.0252111 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0247509 |
| KLF6 | Kruppel-like factor 6 | -0.0242685 |
| RPL35 | ribosomal protein L35 | -0.0241662 |
| IER3 | immediate early response 3 | -0.0239848 |
| RPS5 | ribosomal protein S5 | -0.0236371 |
| RPS19 | ribosomal protein S19 | -0.0232101 |
| RPL37A | ribosomal protein L37a | -0.022713 |
| GLIS3 | GLIS family zinc finger 3 | -0.0226731 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0226204 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0225479 |
| MKI67 | marker of proliferation Ki-67 | -0.0224756 |
| FTL | ferritin, light polypeptide | -0.0224459 |
