| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.189459 |
| TMEM41B | transmembrane protein 41B | 0.118801 |
| VMP1 | vacuole membrane protein 1 | 0.0916013 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0865393 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0843134 |
| VIM | vimentin | 0.0841525 |
| MGAT4C | MGAT4 family, member C | 0.0713944 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0686008 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0588768 |
| ANXA1 | annexin A1 | 0.0549806 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0505217 |
| XPO1 | exportin 1 | 0.0479102 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0452383 |
| CPOX | coproporphyrinogen oxidase | 0.0448086 |
| EPHA6 | EPH receptor A6 | 0.0445321 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0444253 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0434438 |
| KIF5B | kinesin family member 5B | 0.0426774 |
| CEP192 | centrosomal protein 192kDa | 0.039707 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0388453 |
| RRM2 | ribonucleotide reductase M2 | 0.0383092 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0378036 |
| VCL | vinculin | 0.037632 |
| PCBP2 | poly(rC) binding protein 2 | 0.0373844 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0363794 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0362799 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0359399 |
| CCNL1 | cyclin L1 | 0.0359159 |
| PTMS | parathymosin | 0.0355377 |
| JMJD1C | jumonji domain containing 1C | 0.0352934 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0350682 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0340374 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0338217 |
| SET | SET nuclear proto-oncogene | 0.0335354 |
| CLDND1 | claudin domain containing 1 | 0.0334122 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0324075 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0323462 |
| ATP11A | ATPase, class VI, type 11A | 0.0323079 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0321183 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0317751 |
| SYT1 | synaptotagmin I | 0.0316036 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313159 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0312839 |
| RPS12 | ribosomal protein S12 | 0.029913 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0295559 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0294937 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0290726 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0289966 |
| HELB | helicase (DNA) B | 0.0282836 |
| RTN4 | reticulon 4 | 0.0281601 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0279166 |
| CENPE | centromere protein E, 312kDa | 0.0276028 |
| TPM3 | tropomyosin 3 | 0.0273604 |
| CASC3 | cancer susceptibility candidate 3 | 0.0273138 |
| USP53 | ubiquitin specific peptidase 53 | 0.0272963 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0272212 |
| WDR43 | WD repeat domain 43 | 0.0271537 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0268699 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0268587 |
| ZNF292 | zinc finger protein 292 | 0.026434 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0263511 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0258717 |
| MCL1 | myeloid cell leukemia 1 | 0.0257047 |
| BRD2 | bromodomain containing 2 | 0.0256085 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0255143 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0253766 |
| SP3 | Sp3 transcription factor | 0.0252651 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.02513 |
| PHF21A | PHD finger protein 21A | 0.025112 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0250699 |
| CEP70 | centrosomal protein 70kDa | 0.0249795 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.024825 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0247653 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0247543 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0245986 |
| OGA | O-GlcNAcase | 0.0245383 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0243532 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0240594 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239814 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0238642 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0235382 |
| CEP95 | centrosomal protein 95kDa | 0.023475 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0233203 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0230698 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0230624 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0230092 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0229832 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.022907 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0228932 |
| ECT2 | epithelial cell transforming 2 | 0.0228872 |
| RPS2 | ribosomal protein S2 | 0.0228445 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0228387 |
| PGK1 | phosphoglycerate kinase 1 | 0.0228171 |
| NEBL | nebulette | 0.0227388 |
| MEMO1 | mediator of cell motility 1 | 0.022664 |
| RBM25 | RNA binding motif protein 25 | 0.0226095 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0225963 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0225962 |
| YME1L1 | YME1-like 1 ATPase | 0.0225605 |
| SUCO | SUN domain containing ossification factor | 0.0224989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150034 |
| NLGN1 | neuroligin 1 | -0.121192 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.119905 |
| PCDH7 | protocadherin 7 | -0.102108 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0997758 |
| EHBP1 | EH domain binding protein 1 | -0.0735099 |
| HMGA1 | high mobility group AT-hook 1 | -0.0723613 |
| HMGA2 | high mobility group AT-hook 2 | -0.0711548 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0685059 |
| RASAL2 | RAS protein activator like 2 | -0.0668515 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0619492 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0588324 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0578137 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0577878 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.05685 |
| ACTG1 | actin gamma 1 | -0.0558157 |
| DST | dystonin | -0.0512326 |
| CCND1 | cyclin D1 | -0.0512248 |
| RPL35A | ribosomal protein L35a | -0.0497581 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0484516 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0483125 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0480537 |
| AHNAK | AHNAK nucleoprotein | -0.0470082 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0466716 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0461001 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0444484 |
| PTMA | prothymosin, alpha | -0.0433645 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0422544 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0413782 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0400234 |
| RNF213 | ring finger protein 213 | -0.039042 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0381016 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380268 |
| RPL23 | ribosomal protein L23 | -0.0374741 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0353479 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350724 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0350682 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0349885 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0343933 |
| H1-0 | H1.0 linker histone | -0.0339905 |
| ZNF217 | zinc finger protein 217 | -0.0334539 |
| RPS24 | ribosomal protein S24 | -0.0333175 |
| POTEF | POTE ankyrin domain family, member F | -0.0327375 |
| CMIP | c-Maf inducing protein | -0.0326304 |
| EGR1 | early growth response 1 | -0.032628 |
| RPL34 | ribosomal protein L34 | -0.0303196 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0301227 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0298319 |
| EXOC4 | exocyst complex component 4 | -0.0293968 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0292806 |
| RPL38 | ribosomal protein L38 | -0.0292122 |
| PARD3 | par-3 family cell polarity regulator | -0.0291541 |
| INTS6 | integrator complex subunit 6 | -0.0287178 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0285928 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0282814 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0282534 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0278227 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0274199 |
| RPLP0 | ribosomal protein, large, P0 | -0.0273575 |
| KLF6 | Kruppel-like factor 6 | -0.0265735 |
| TMSB10 | thymosin beta 10 | -0.0264818 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0262288 |
| ZNF804A | zinc finger protein 804A | -0.0258931 |
| CANX | calnexin | -0.0258764 |
| GNAS | GNAS complex locus | -0.0257324 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.025702 |
| SUMF1 | sulfatase modifying factor 1 | -0.0253963 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0253863 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0252456 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0252276 |
| RPS27A | ribosomal protein S27a | -0.0249465 |
| CUX1 | cut-like homeobox 1 | -0.0249233 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0248634 |
| RPL12 | ribosomal protein L12 | -0.0241563 |
| RPS20 | ribosomal protein S20 | -0.0239582 |
| CEP112 | centrosomal protein 112kDa | -0.0237678 |
| RPL26 | ribosomal protein L26 | -0.0236215 |
| CLDN1 | claudin 1 | -0.0236064 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0235333 |
| SACS | sacsin molecular chaperone | -0.0234552 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0233953 |
| HMGB1 | high mobility group box 1 | -0.0232863 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0231717 |
| TPI1 | triosephosphate isomerase 1 | -0.0231414 |
| RPL11 | ribosomal protein L11 | -0.0230707 |
| EDARADD | EDAR-associated death domain | -0.022724 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0225306 |
| NABP1 | nucleic acid binding protein 1 | -0.0225239 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0224966 |
| FAT1 | FAT atypical cadherin 1 | -0.0224508 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0223169 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0221777 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0220109 |
| ANK2 | ankyrin 2, neuronal | -0.0218584 |
| EGFR | epidermal growth factor receptor | -0.0217907 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0217874 |
| GPHN | gephyrin | -0.0217132 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0214134 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0213249 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0212285 |
