| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0984774 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0704275 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0610978 |
| HLA-B | major histocompatibility complex, class I, B | 0.0608151 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0552756 |
| PTMA | prothymosin, alpha | 0.0543465 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.051904 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0496146 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.048508 |
| APOL1 | apolipoprotein L, 1 | 0.0472535 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0457924 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0446476 |
| CAVIN1 | caveolae associated protein 1 | 0.0443128 |
| GOLGA4 | golgin A4 | 0.0437945 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0413845 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0412865 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0402116 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0393215 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0364834 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0361688 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0353911 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0353586 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0351022 |
| OGA | O-GlcNAcase | 0.0346 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0345586 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0342209 |
| ARRDC3 | arrestin domain containing 3 | 0.0338396 |
| CDK13 | cyclin-dependent kinase 13 | 0.0338154 |
| SDC4 | syndecan 4 | 0.0336975 |
| VIM | vimentin | 0.0333096 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0328232 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0326489 |
| ANLN | anillin, actin binding protein | 0.0325603 |
| APP | amyloid beta (A4) precursor protein | 0.0320626 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0317111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0314742 |
| RPL37A | ribosomal protein L37a | 0.0313494 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0310442 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0305522 |
| SEPTIN9 | septin 9 | 0.0302197 |
| RHEB | Ras homolog enriched in brain | 0.0299873 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0296387 |
| ITGAV | integrin, alpha V | 0.0294728 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0292352 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0288711 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0288018 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.028754 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.028716 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0286238 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0285211 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0284279 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0283016 |
| MPZL1 | myelin protein zero-like 1 | 0.0280502 |
| VCL | vinculin | 0.0279725 |
| XPO1 | exportin 1 | 0.0279654 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0279462 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0277796 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0276591 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0275999 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0275661 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0274818 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0274627 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0271987 |
| KLHDC10 | kelch domain containing 10 | 0.0271408 |
| JAK1 | Janus kinase 1 | 0.0270454 |
| PGK1 | phosphoglycerate kinase 1 | 0.0270319 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0269728 |
| TPR | translocated promoter region, nuclear basket protein | 0.0269516 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0265422 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0263477 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0261233 |
| CALR | calreticulin | 0.0258672 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0255309 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0251695 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0246335 |
| TGFB2 | transforming growth factor, beta 2 | 0.0241331 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0240947 |
| USP47 | ubiquitin specific peptidase 47 | 0.0237249 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0234537 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0232958 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 0.0231739 |
| YME1L1 | YME1-like 1 ATPase | 0.0231677 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0230889 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0230884 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0227052 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0226823 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0225404 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0223202 |
| TMEM263 | transmembrane protein 263 | 0.0220934 |
| GOLGA2 | golgin A2 | 0.0220108 |
| RBM25 | RNA binding motif protein 25 | 0.0219889 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0219734 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0219274 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0217561 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0216051 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0214749 |
| TRIM24 | tripartite motif containing 24 | 0.0213983 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.0213823 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0213181 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0212438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.260464 |
| POTEF | POTE ankyrin domain family, member F | -0.156575 |
| FRMD4A | FERM domain containing 4A | -0.145815 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128653 |
| CD44 | CD44 molecule (Indian blood group) | -0.110544 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0926758 |
| GPC6 | glypican 6 | -0.0859436 |
| FTL | ferritin, light polypeptide | -0.084 |
| PFN1 | profilin 1 | -0.08321 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0827989 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0827127 |
| ASPH | aspartate beta-hydroxylase | -0.0812884 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0809981 |
| GLIS3 | GLIS family zinc finger 3 | -0.0757403 |
| RNF213 | ring finger protein 213 | -0.0704923 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0688786 |
| MAP1B | microtubule-associated protein 1B | -0.0560162 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.055807 |
| RAI14 | retinoic acid induced 14 | -0.0539525 |
| RIGI | RNA sensor RIG-I | -0.0520919 |
| MX1 | MX dynamin-like GTPase 1 | -0.0518114 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0505664 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0495576 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0485721 |
| TXNRD1 | thioredoxin reductase 1 | -0.0463476 |
| NDRG1 | N-myc downstream regulated 1 | -0.0462291 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0444706 |
| MYADM | myeloid-associated differentiation marker | -0.043379 |
| EHBP1 | EH domain binding protein 1 | -0.0432407 |
| DGKI | diacylglycerol kinase, iota | -0.0422721 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0419374 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0412726 |
| TAGLN2 | transgelin 2 | -0.041022 |
| IFI44L | interferon-induced protein 44-like | -0.040492 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.039522 |
| PKM | pyruvate kinase, muscle | -0.0393781 |
| GDF15 | growth differentiation factor 15 | -0.0393573 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0376174 |
| FAT1 | FAT atypical cadherin 1 | -0.0372499 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0370097 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0367516 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0352537 |
| HMGA1 | high mobility group AT-hook 1 | -0.0351865 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0351572 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0351384 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0346649 |
| RPS20 | ribosomal protein S20 | -0.0344555 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0340436 |
| SDCBP | syndecan binding protein (syntenin) | -0.0339415 |
| TUSC3 | tumor suppressor candidate 3 | -0.0336823 |
| KYNU | kynureninase | -0.0335901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0335821 |
| BNC2 | basonuclin 2 | -0.0330372 |
| EGFR | epidermal growth factor receptor | -0.0329751 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0322456 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0316209 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0315612 |
| SON | SON DNA binding protein | -0.0311433 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0310954 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0310626 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0308571 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0307523 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0307368 |
| TUBA1B | tubulin, alpha 1b | -0.0305974 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0305737 |
| RPL28 | ribosomal protein L28 | -0.0303559 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0303515 |
| RUNX1 | runt-related transcription factor 1 | -0.02988 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294236 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0293664 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0292527 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0288402 |
| TMSB10 | thymosin beta 10 | -0.028688 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0280663 |
| CTSD | cathepsin D | -0.0279302 |
| CXXC1 | CXXC finger protein 1 | -0.027794 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.027789 |
| RPS2 | ribosomal protein S2 | -0.0276711 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0276306 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0273983 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0272852 |
| FLNA | filamin A, alpha | -0.0271356 |
| RPS4X | ribosomal protein S4, X-linked | -0.0267999 |
| HMGB1 | high mobility group box 1 | -0.0265984 |
| PML | promyelocytic leukemia | -0.0264355 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0263618 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0260985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0260082 |
| FLNC | filamin C, gamma | -0.0257151 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0256861 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0254242 |
| ZNF207 | zinc finger protein 207 | -0.0253353 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0248286 |
| DST | dystonin | -0.0244411 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0243523 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0240656 |
| LAMA5 | laminin, alpha 5 | -0.0240199 |
| DIAPH3 | diaphanous-related formin 3 | -0.0239191 |
| SP100 | SP100 nuclear antigen | -0.0238901 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0237899 |
