| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.121453 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.109726 |
| MT1X | metallothionein 1X | 0.0846532 |
| VIM | vimentin | 0.0537547 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0443823 |
| PTMA | prothymosin, alpha | 0.0439586 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0418439 |
| USP3 | ubiquitin specific peptidase 3 | 0.0415938 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0393105 |
| RTN4 | reticulon 4 | 0.0367259 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0356005 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0355242 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0341558 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0334547 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0326462 |
| OGA | O-GlcNAcase | 0.0321109 |
| B2M | beta-2-microglobulin | 0.0312863 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0312784 |
| GOLGA4 | golgin A4 | 0.0306031 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0301091 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0290976 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0285459 |
| CDCA2 | cell division cycle associated 2 | 0.027666 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0273227 |
| NGLY1 | N-glycanase 1 | 0.0267661 |
| TMSB10 | thymosin beta 10 | 0.0257569 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0253775 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0250746 |
| TBK1 | TANK-binding kinase 1 | 0.0241822 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0240567 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0233425 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0232783 |
| AXL | AXL receptor tyrosine kinase | 0.0232682 |
| HELZ | helicase with zinc finger | 0.0229982 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0227268 |
| ATP13A3 | ATPase type 13A3 | 0.0223463 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0220826 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0219342 |
| USP47 | ubiquitin specific peptidase 47 | 0.0215296 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0209709 |
| FAM107B | family with sequence similarity 107, member B | 0.0208914 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0207475 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0207292 |
| ANLN | anillin, actin binding protein | 0.0206406 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0205915 |
| RBM25 | RNA binding motif protein 25 | 0.0204553 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.020142 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0200604 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.020033 |
| NUP58 | nucleoporin 58 | 0.0199656 |
| CEP95 | centrosomal protein 95kDa | 0.0199471 |
| MSN | moesin | 0.0199229 |
| SPAG9 | sperm associated antigen 9 | 0.0198649 |
| FMNL2 | formin-like 2 | 0.0193394 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0192767 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0192428 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0192063 |
| WDR43 | WD repeat domain 43 | 0.0190307 |
| MKI67 | marker of proliferation Ki-67 | 0.0190218 |
| RASA2 | RAS p21 protein activator 2 | 0.018803 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0187943 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0187273 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0185891 |
| PDCD5 | programmed cell death 5 | 0.0184515 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0184419 |
| THOC2 | THO complex 2 | 0.0181415 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0178914 |
| SUCO | SUN domain containing ossification factor | 0.0178303 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0177965 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0174207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0174103 |
| RRM2 | ribonucleotide reductase M2 | 0.0173427 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0172818 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0171601 |
| CDC27 | cell division cycle 27 | 0.0170242 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.016992 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0168533 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0168245 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0163864 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0163063 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.0161032 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0160982 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0160257 |
| DENND5A | DENN/MADD domain containing 5A | 0.0158704 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.01574 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0157151 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0155574 |
| FA2H | fatty acid 2-hydroxylase | 0.0155466 |
| SBF2 | SET binding factor 2 | 0.0155208 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0155185 |
| RPS19 | ribosomal protein S19 | 0.0154558 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0154358 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0153742 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0153537 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0153404 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0152686 |
| SMAD4 | SMAD family member 4 | 0.0152651 |
| CD47 | CD47 molecule | 0.0152284 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0152237 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0151748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.362039 |
| EFNA5 | ephrin-A5 | -0.143964 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.135353 |
| PDE10A | phosphodiesterase 10A | -0.121722 |
| EGFR | epidermal growth factor receptor | -0.106732 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.104028 |
| KYNU | kynureninase | -0.101996 |
| RNF213 | ring finger protein 213 | -0.10092 |
| EXT1 | exostosin glycosyltransferase 1 | -0.092573 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0910359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0881779 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0872276 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0818588 |
| NDRG1 | N-myc downstream regulated 1 | -0.0814503 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0801549 |
| AUTS2 | autism susceptibility candidate 2 | -0.0774787 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0735779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0719466 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0712691 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0699239 |
| ACTG1 | actin gamma 1 | -0.0682256 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0675548 |
| AHNAK | AHNAK nucleoprotein | -0.0618306 |
| MYO1E | myosin IE | -0.0616062 |
| INTS6 | integrator complex subunit 6 | -0.0614981 |
| EHBP1 | EH domain binding protein 1 | -0.0594296 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0593012 |
| SP100 | SP100 nuclear antigen | -0.0582191 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0582135 |
| VCL | vinculin | -0.0581459 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0576403 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0560842 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0541442 |
| RHCG | Rh family, C glycoprotein | -0.052528 |
| TNS3 | tensin 3 | -0.0520166 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0517123 |
| PRKCA | protein kinase C, alpha | -0.0516672 |
| ASPH | aspartate beta-hydroxylase | -0.0514963 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0512474 |
| ANXA2 | annexin A2 | -0.0490726 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0486194 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0481919 |
| GLIS3 | GLIS family zinc finger 3 | -0.0477794 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0466012 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0465908 |
| ANXA1 | annexin A1 | -0.0460914 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | -0.045453 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0452854 |
| PALLD | palladin, cytoskeletal associated protein | -0.0452283 |
| RIGI | RNA sensor RIG-I | -0.0449675 |
| LDHA | lactate dehydrogenase A | -0.0445543 |
| SQSTM1 | sequestosome 1 | -0.0444778 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0441575 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0435176 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0429635 |
| TPM1 | tropomyosin 1 (alpha) | -0.0427522 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0424294 |
| AADAC | arylacetamide deacetylase | -0.0422402 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.041712 |
| PRKCE | protein kinase C, epsilon | -0.0414832 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.040411 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0401646 |
| NRG1 | neuregulin 1 | -0.0393853 |
| RAD51B | RAD51 paralog B | -0.0386969 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.038437 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0383627 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0380267 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0376995 |
| CUX1 | cut-like homeobox 1 | -0.0375825 |
| FBXO11 | F-box protein 11 | -0.0373599 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0373345 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0372911 |
| GOLGB1 | golgin B1 | -0.0371516 |
| PARD3 | par-3 family cell polarity regulator | -0.0369274 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0364494 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0362889 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0360506 |
| CANX | calnexin | -0.035513 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0347897 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0345226 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0344958 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0343695 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0342652 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0338234 |
| DUSP16 | dual specificity phosphatase 16 | -0.0337716 |
| ATG7 | autophagy related 7 | -0.0336949 |
| PKM | pyruvate kinase, muscle | -0.0336146 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0331243 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0330099 |
| MCU | mitochondrial calcium uniporter | -0.0328201 |
| LMO7 | LIM domain 7 | -0.0327544 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0325642 |
| ZNF609 | zinc finger protein 609 | -0.0325185 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324895 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.032213 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0319827 |
| BICC1 | BicC family RNA binding protein 1 | -0.0316527 |
| EXOC4 | exocyst complex component 4 | -0.0316233 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0315402 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0315075 |
