| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0871646 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0844291 |
| EZR | ezrin | 0.0710528 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0690169 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0561241 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0558963 |
| RBM39 | RNA binding motif protein 39 | 0.0551862 |
| PTK2 | protein tyrosine kinase 2 | 0.053946 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0531555 |
| B2M | beta-2-microglobulin | 0.0531408 |
| SPAG9 | sperm associated antigen 9 | 0.0490751 |
| TMSB4X | thymosin beta 4, X-linked | 0.0488602 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0466683 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0461754 |
| OGA | O-GlcNAcase | 0.0444575 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.044343 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0427667 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0423639 |
| SMAD3 | SMAD family member 3 | 0.042228 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0420463 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0363094 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0362327 |
| SUCO | SUN domain containing ossification factor | 0.0361672 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0355307 |
| NCKAP1 | NCK-associated protein 1 | 0.0351435 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0345388 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0345263 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0342109 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0341336 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0334342 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0329735 |
| YTHDC1 | YTH domain containing 1 | 0.0325239 |
| MYO6 | myosin VI | 0.0323923 |
| ZNF292 | zinc finger protein 292 | 0.0321782 |
| SIK3 | SIK family kinase 3 | 0.0321047 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0308234 |
| RPL14 | ribosomal protein L14 | 0.0303169 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0300577 |
| ANKRD11 | ankyrin repeat domain 11 | 0.030017 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0295759 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0294963 |
| RPS2 | ribosomal protein S2 | 0.0287787 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0284496 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0283748 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280062 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0280043 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0278689 |
| MATR3 | matrin 3 | 0.0275572 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.027158 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0263451 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0263153 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0259623 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0257865 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0256048 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0252169 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0252164 |
| PMM2 | phosphomannomutase 2 | 0.0251634 |
| TOP1 | topoisomerase (DNA) I | 0.0250901 |
| RHEB | Ras homolog enriched in brain | 0.0248845 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.024492 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0244144 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0244058 |
| CRY1 | cryptochrome circadian clock 1 | 0.0242052 |
| ABI1 | abl-interactor 1 | 0.0233239 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0233005 |
| POU2F1 | POU class 2 homeobox 1 | 0.0231983 |
| RBM33 | RNA binding motif protein 33 | 0.0231641 |
| OXSR1 | oxidative stress responsive 1 | 0.0230594 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.0228585 |
| MTMR3 | myotubularin related protein 3 | 0.0228002 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0227397 |
| RNF145 | ring finger protein 145 | 0.0225695 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0225548 |
| KRT8 | keratin 8, type II | 0.0223646 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.022336 |
| FAM168B | family with sequence similarity 168, member B | 0.0222694 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0218853 |
| NOP58 | NOP58 ribonucleoprotein | 0.0216594 |
| TMEM41B | transmembrane protein 41B | 0.0216306 |
| PLEC | plectin | 0.0215775 |
| VMP1 | vacuole membrane protein 1 | 0.0214698 |
| KIF5B | kinesin family member 5B | 0.0212711 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0212554 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0211844 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0211125 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0210311 |
| QKI | QKI, KH domain containing, RNA binding | 0.0208537 |
| NEK7 | NIMA-related kinase 7 | 0.0206402 |
| SDC4 | syndecan 4 | 0.020634 |
| HBP1 | HMG-box transcription factor 1 | 0.0204722 |
| CCNY | cyclin Y | 0.0203283 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0203011 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.020279 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.020135 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.02013 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198309 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0198208 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0196979 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0196132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.228612 |
| POTEF | POTE ankyrin domain family, member F | -0.200766 |
| NDRG1 | N-myc downstream regulated 1 | -0.19055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177269 |
| MUC17 | mucin 17, cell surface associated | -0.13828 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.134175 |
| FLNB | filamin B, beta | -0.120062 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.106161 |
| HMGA1 | high mobility group AT-hook 1 | -0.0965463 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0877894 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.086888 |
| S100A10 | S100 calcium binding protein A10 | -0.0860073 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0847694 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0812607 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0806089 |
| DSG2 | desmoglein 2 | -0.0774419 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.076776 |
| LDHA | lactate dehydrogenase A | -0.0752493 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0751554 |
| ITGA6 | integrin, alpha 6 | -0.0691252 |
| TXNIP | thioredoxin interacting protein | -0.0687614 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0685051 |
| UBC | ubiquitin C | -0.0679008 |
| TMSB10 | thymosin beta 10 | -0.0667789 |
| VCAN | versican | -0.0653818 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.064629 |
| S100A11 | S100 calcium binding protein A11 | -0.0641113 |
| EGFR | epidermal growth factor receptor | -0.0639331 |
| LAMB3 | laminin, beta 3 | -0.0601221 |
| ANXA2 | annexin A2 | -0.0579531 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0569706 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0559462 |
| NPSR1 | neuropeptide S receptor 1 | -0.0552775 |
| PERP | PERP, TP53 apoptosis effector | -0.0546929 |
| KLK10 | kallikrein-related peptidase 10 | -0.0537511 |
| LAMA4 | laminin, alpha 4 | -0.0525066 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0523165 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.051752 |
| CDCP1 | CUB domain containing protein 1 | -0.0513257 |
| ITGB4 | integrin, beta 4 | -0.05099 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0499896 |
| FAM3C | family with sequence similarity 3, member C | -0.0480317 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0480071 |
| VIM | vimentin | -0.0477359 |
| EGR1 | early growth response 1 | -0.0473019 |
| FTL | ferritin, light polypeptide | -0.0469923 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0468917 |
| KLF6 | Kruppel-like factor 6 | -0.0458936 |
| HMGA2 | high mobility group AT-hook 2 | -0.0447413 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0429334 |
| PTMA | prothymosin, alpha | -0.0427076 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0408073 |
| KRT19 | keratin 19, type I | -0.0407687 |
| FERMT1 | fermitin family member 1 | -0.0403896 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0395164 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0394981 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0387264 |
| RPL35A | ribosomal protein L35a | -0.0381716 |
| RPLP0 | ribosomal protein, large, P0 | -0.038171 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0377804 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0377082 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0375633 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0368233 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0367174 |
| CD9 | CD9 molecule | -0.0359285 |
| PFN1 | profilin 1 | -0.0356409 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0356109 |
| AHNAK | AHNAK nucleoprotein | -0.0352909 |
| DIAPH2 | diaphanous-related formin 2 | -0.0349394 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0347486 |
| RNF213 | ring finger protein 213 | -0.0346227 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.034245 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0341591 |
| MXD1 | MAX dimerization protein 1 | -0.0338278 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0337267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333147 |
| ENO1 | enolase 1, (alpha) | -0.0325896 |
| CD44 | CD44 molecule (Indian blood group) | -0.0322933 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0321012 |
| CSTB | cystatin B (stefin B) | -0.0317979 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0315707 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0314902 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0313317 |
| RIGI | RNA sensor RIG-I | -0.0311192 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0307821 |
| PKM | pyruvate kinase, muscle | -0.030754 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0305894 |
| TXNRD1 | thioredoxin reductase 1 | -0.0304599 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0304479 |
| ASPH | aspartate beta-hydroxylase | -0.0304219 |
| JUP | junction plakoglobin | -0.0302923 |
| CLMP | CXADR-like membrane protein | -0.0301999 |
| TUBA1B | tubulin, alpha 1b | -0.0301724 |
| MYO1E | myosin IE | -0.0301031 |
| PRSS3 | protease, serine, 3 | -0.029774 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0294815 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0292501 |
| S100A6 | S100 calcium binding protein A6 | -0.0285117 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0284021 |
| TPM4 | tropomyosin 4 | -0.0283097 |
