| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0860905 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0595277 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0532879 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0439474 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0402818 |
| NDRG1 | N-myc downstream regulated 1 | 0.0398602 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0390502 |
| VCL | vinculin | 0.0369617 |
| TMEM41B | transmembrane protein 41B | 0.0355896 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0334434 |
| RTN4 | reticulon 4 | 0.0314786 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0302345 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0294463 |
| ACTN4 | actinin, alpha 4 | 0.0291099 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0287037 |
| B2M | beta-2-microglobulin | 0.0278566 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02762 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0264178 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0260081 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0258359 |
| SDC4 | syndecan 4 | 0.0256738 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0256707 |
| MYO6 | myosin VI | 0.0254261 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0254058 |
| SPAG9 | sperm associated antigen 9 | 0.024041 |
| ABI1 | abl-interactor 1 | 0.0240075 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0237761 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0233133 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232621 |
| MCL1 | myeloid cell leukemia 1 | 0.0229711 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0229393 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0227138 |
| RASA2 | RAS p21 protein activator 2 | 0.0225401 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0223243 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0217672 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0217386 |
| FDPS | farnesyl diphosphate synthase | 0.0216979 |
| FOXO3 | forkhead box O3 | 0.021648 |
| ZNF292 | zinc finger protein 292 | 0.0213554 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0213412 |
| TMEM165 | transmembrane protein 165 | 0.0210474 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0208245 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0206632 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0203955 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0203071 |
| SUCO | SUN domain containing ossification factor | 0.0201364 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.019846 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0198419 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0195504 |
| CEP95 | centrosomal protein 95kDa | 0.0194975 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0193948 |
| OGA | O-GlcNAcase | 0.0192093 |
| RCOR1 | REST corepressor 1 | 0.0190632 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0189654 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0189586 |
| DENND5A | DENN/MADD domain containing 5A | 0.0189356 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0187703 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0187684 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.018658 |
| FAM168A | family with sequence similarity 168, member A | 0.0186489 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0186319 |
| USP53 | ubiquitin specific peptidase 53 | 0.0177819 |
| WDR45B | WD repeat domain 45B | 0.0176822 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0176565 |
| LDLR | low density lipoprotein receptor | 0.0173162 |
| CUL3 | cullin 3 | 0.0172728 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0171973 |
| CLIC4 | chloride intracellular channel 4 | 0.017143 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0170622 |
| WASF2 | WAS protein family, member 2 | 0.0170451 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0170031 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0168665 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0166129 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0165687 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0164463 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0163279 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0162847 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0162115 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0160992 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0160366 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0160076 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0158896 |
| CCNL1 | cyclin L1 | 0.0157812 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0157728 |
| PGK1 | phosphoglycerate kinase 1 | 0.0157573 |
| VGLL4 | vestigial-like family member 4 | 0.0156762 |
| ZSWIM4 | zinc finger, SWIM-type containing 4 | 0.0156041 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0155097 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0154985 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0154822 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0154151 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0153321 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0152637 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0151743 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.014881 |
| LPIN2 | lipin 2 | 0.0148401 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0148335 |
| AZIN1 | antizyme inhibitor 1 | 0.0147687 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0147136 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0146932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.189041 |
| RPL19 | ribosomal protein L19 | -0.1369 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.132551 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.132317 |
| ASPH | aspartate beta-hydroxylase | -0.119588 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.116667 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0725826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0711813 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0675374 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0670399 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0632303 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0604605 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.056163 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0556958 |
| NTN4 | netrin 4 | -0.0544559 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0533467 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0526519 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0488818 |
| CDK12 | cyclin-dependent kinase 12 | -0.0476715 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.046562 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0439977 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0439337 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0423818 |
| OSMR | oncostatin M receptor | -0.0415831 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0415592 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.041149 |
| CCND1 | cyclin D1 | -0.0410724 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.040292 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0397789 |
| TMC5 | transmembrane channel-like 5 | -0.0389248 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0381489 |
| SMYD3 | SET and MYND domain containing 3 | -0.036593 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.035243 |
| DSPP | dentin sialophosphoprotein | -0.0350557 |
| POTEF | POTE ankyrin domain family, member F | -0.0346586 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0327124 |
| NCOA7 | nuclear receptor coactivator 7 | -0.032241 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0314371 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0313517 |
| TC2N | tandem C2 domains, nuclear | -0.0310048 |
| FGB | fibrinogen beta chain | -0.0305466 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0297443 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0293357 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0282151 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0281249 |
| GLCCI1 | glucocorticoid induced 1 | -0.0279832 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0275381 |
| NRP1 | neuropilin 1 | -0.0272776 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0271349 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0270098 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0268587 |
| RPL35A | ribosomal protein L35a | -0.0267916 |
| INSR | insulin receptor | -0.0261231 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0260213 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.0258972 |
| NFIA | nuclear factor I/A | -0.0255319 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0254745 |
| RPS6 | ribosomal protein S6 | -0.0249864 |
| SET | SET nuclear proto-oncogene | -0.0249019 |
| MYO1B | myosin IB | -0.0243924 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0239865 |
| MACROD2 | MACRO domain containing 2 | -0.0238994 |
| EXOC4 | exocyst complex component 4 | -0.0238386 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0237684 |
| EGFR | epidermal growth factor receptor | -0.0237343 |
| EFNA5 | ephrin-A5 | -0.0235702 |
| SGMS1 | sphingomyelin synthase 1 | -0.0234346 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0232959 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0232863 |
| SYTL2 | synaptotagmin-like 2 | -0.023171 |
| ATXN1 | ataxin 1 | -0.0230807 |
| MBD4 | methyl-CpG binding domain protein 4 | -0.0230119 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0228446 |
| DUSP16 | dual specificity phosphatase 16 | -0.0228117 |
| AHR | aryl hydrocarbon receptor | -0.022756 |
| LASP1 | LIM and SH3 protein 1 | -0.022681 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0225781 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0221637 |
| ANXA2 | annexin A2 | -0.022113 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0220589 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0220314 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0218381 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0216753 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0216466 |
| DENND1A | DENN/MADD domain containing 1A | -0.0214128 |
| ITGB6 | integrin, beta 6 | -0.0213586 |
| DUSP4 | dual specificity phosphatase 4 | -0.0212296 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0211617 |
| AREG | amphiregulin | -0.0209913 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0209776 |
| RPL8 | ribosomal protein L8 | -0.0209673 |
| RNF213 | ring finger protein 213 | -0.0208964 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0207948 |
| SP100 | SP100 nuclear antigen | -0.020471 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0203021 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0202815 |
| SLFN5 | schlafen family member 5 | -0.0201255 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.020022 |
| SPTSSB | serine palmitoyltransferase, small subunit B | -0.0198414 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0197986 |
