| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.180701 |
| FMNL2 | formin-like 2 | 0.0985379 |
| NEBL | nebulette | 0.0927858 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0885389 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0806827 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0750745 |
| OGA | O-GlcNAcase | 0.0740151 |
| B2M | beta-2-microglobulin | 0.0695738 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.064679 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0589712 |
| VCL | vinculin | 0.0574451 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0568755 |
| ATRN | attractin | 0.0554801 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0544505 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0540861 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0539025 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0485573 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.048407 |
| PHIP | pleckstrin homology domain interacting protein | 0.0451286 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0439572 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0428661 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0428331 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0426248 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0413914 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0410625 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0405433 |
| NGLY1 | N-glycanase 1 | 0.0400555 |
| RPL14 | ribosomal protein L14 | 0.0397004 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0394597 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0385412 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0383674 |
| JMJD1C | jumonji domain containing 1C | 0.0382097 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0372427 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0360105 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.035088 |
| ZNF638 | zinc finger protein 638 | 0.0349517 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0349463 |
| MAPT | microtubule-associated protein tau | 0.0341243 |
| RNF130 | ring finger protein 130 | 0.0339168 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328472 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0316744 |
| VIM | vimentin | 0.0316195 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0314751 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0314463 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0311747 |
| MEMO1 | mediator of cell motility 1 | 0.0307647 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0305185 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0300967 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0298056 |
| FAM168A | family with sequence similarity 168, member A | 0.0297472 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0297139 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0296647 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0295447 |
| MEF2A | myocyte enhancer factor 2A | 0.0294144 |
| QKI | QKI, KH domain containing, RNA binding | 0.0288801 |
| KMT5B | lysine methyltransferase 5B | 0.0285095 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0282035 |
| SET | SET nuclear proto-oncogene | 0.0276499 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0276073 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0273878 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0273675 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0269453 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0268575 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0266868 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0266164 |
| GLMN | glomulin, FKBP associated protein | 0.0266164 |
| ZNF292 | zinc finger protein 292 | 0.0263158 |
| FUS | FUS RNA binding protein | 0.0259707 |
| ZNF146 | zinc finger protein 146 | 0.0258853 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0256873 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0255268 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0254679 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0254479 |
| PCM1 | pericentriolar material 1 | 0.0253697 |
| TRIM33 | tripartite motif containing 33 | 0.0253688 |
| RNF220 | ring finger protein 220 | 0.0250305 |
| USP28 | ubiquitin specific peptidase 28 | 0.0247511 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0244192 |
| RBM26 | RNA binding motif protein 26 | 0.0243435 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0242903 |
| CCNY | cyclin Y | 0.024206 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0241611 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0240501 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0240339 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0237592 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0236485 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0235078 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0234316 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0234293 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.023425 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0231961 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0230776 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0230188 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0229852 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0229722 |
| USP37 | ubiquitin specific peptidase 37 | 0.0228905 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0227178 |
| DENND5A | DENN/MADD domain containing 5A | 0.0226233 |
| LRRC1 | leucine rich repeat containing 1 | 0.0226185 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0225954 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.184703 |
| TENM3 | teneurin transmembrane protein 3 | -0.170591 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.161508 |
| CADM2 | cell adhesion molecule 2 | -0.128079 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.120921 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.106445 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0707786 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0661738 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0661375 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0638523 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0594782 |
| RIGI | RNA sensor RIG-I | -0.0572561 |
| RAD51B | RAD51 paralog B | -0.0554516 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0541378 |
| DST | dystonin | -0.0511522 |
| EGR1 | early growth response 1 | -0.0505108 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0500134 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0495053 |
| ADAR | adenosine deaminase, RNA-specific | -0.0478014 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0475409 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0468641 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0462594 |
| MKI67 | marker of proliferation Ki-67 | -0.0451913 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0450534 |
| RPL11 | ribosomal protein L11 | -0.0405985 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0385845 |
| BNC2 | basonuclin 2 | -0.0375744 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0374197 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0370785 |
| ATG10 | autophagy related 10 | -0.0366809 |
| RPL9 | ribosomal protein L9 | -0.0366248 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0364533 |
| UBC | ubiquitin C | -0.0358819 |
| RPLP1 | ribosomal protein, large, P1 | -0.035865 |
| BPTF | bromodomain PHD finger transcription factor | -0.0358551 |
| IPO7 | importin 7 | -0.0358406 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.0337729 |
| ACTG1 | actin gamma 1 | -0.033466 |
| RPS2 | ribosomal protein S2 | -0.0332634 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0320288 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0318753 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0317075 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0317011 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0316584 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0315135 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0307766 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0303248 |
| FAT1 | FAT atypical cadherin 1 | -0.0296896 |
| RPL7 | ribosomal protein L7 | -0.0293622 |
| TUBA1B | tubulin, alpha 1b | -0.0293219 |
| FBXO11 | F-box protein 11 | -0.0290233 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.028691 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0285339 |
| NRG1 | neuregulin 1 | -0.0284862 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.0280543 |
| CLTC | clathrin, heavy chain (Hc) | -0.028 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0278366 |
| NFIA | nuclear factor I/A | -0.0276837 |
| HMGA1 | high mobility group AT-hook 1 | -0.0272383 |
| NFIB | nuclear factor I/B | -0.0271295 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0269522 |
| DCDC2 | doublecortin domain containing 2 | -0.0265306 |
| KLF10 | Kruppel-like factor 10 | -0.0264322 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0263889 |
| R3HDM1 | R3H domain containing 1 | -0.0261137 |
| POTEF | POTE ankyrin domain family, member F | -0.0257916 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.025753 |
| PMP22 | peripheral myelin protein 22 | -0.0256529 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | -0.025053 |
| METTL15 | methyltransferase like 15 | -0.0248914 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0248869 |
| ANK2 | ankyrin 2, neuronal | -0.0243906 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0243057 |
| SFXN1 | sideroflexin 1 | -0.0241437 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0240369 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0240284 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0239003 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0238592 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0237832 |
| SMYD3 | SET and MYND domain containing 3 | -0.0236716 |
| TTBK2 | tau tubulin kinase 2 | -0.0233039 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0232905 |
| FOXP1 | forkhead box P1 | -0.0232903 |
| RPL23 | ribosomal protein L23 | -0.0231139 |
| TENM2 | teneurin transmembrane protein 2 | -0.0229687 |
| ATP11A | ATPase, class VI, type 11A | -0.022837 |
| RACK1 | receptor for activated C kinase 1 | -0.0227057 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0226921 |
| CEP112 | centrosomal protein 112kDa | -0.0226799 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0225094 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0223365 |
| CDH18 | cadherin 18, type 2 | -0.0223192 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0223115 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0222752 |
| FRYL | FRY-like | -0.0220668 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0220536 |
| HELLS | helicase, lymphoid-specific | -0.0220012 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0219919 |
| R3HDM2 | R3H domain containing 2 | -0.0219669 |
| EXOC4 | exocyst complex component 4 | -0.0219539 |
