| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD109 | CD109 molecule | 0.0894492 |
| COPA | coatomer protein complex, subunit alpha | 0.0683986 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0582503 |
| RNF145 | ring finger protein 145 | 0.0546471 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0495799 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0485706 |
| CDC73 | cell division cycle 73 | 0.0484241 |
| NUP58 | nucleoporin 58 | 0.0440629 |
| ZNF292 | zinc finger protein 292 | 0.0386088 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0383778 |
| PHF21A | PHD finger protein 21A | 0.0375344 |
| MRTFA | myocardin related transcription factor A | 0.0338196 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328793 |
| ZNF654 | zinc finger protein 654 | 0.0320353 |
| GOLGA4 | golgin A4 | 0.0314006 |
| CUL3 | cullin 3 | 0.0308866 |
| SETD5 | SET domain containing 5 | 0.0307669 |
| FMNL2 | formin-like 2 | 0.0303791 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.030123 |
| B2M | beta-2-microglobulin | 0.0296701 |
| RYBP | RING1 and YY1 binding protein | 0.0295557 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.029504 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0279977 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0270205 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0270093 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0263898 |
| ASPH | aspartate beta-hydroxylase | 0.0257813 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254245 |
| VMP1 | vacuole membrane protein 1 | 0.024911 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0247493 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0244431 |
| CABIN1 | calcineurin binding protein 1 | 0.0243972 |
| INSIG2 | insulin induced gene 2 | 0.0240778 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0240534 |
| RBM33 | RNA binding motif protein 33 | 0.0239709 |
| HELZ | helicase with zinc finger | 0.0239139 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.023877 |
| SPAG9 | sperm associated antigen 9 | 0.0236856 |
| TPR | translocated promoter region, nuclear basket protein | 0.0235736 |
| RBM39 | RNA binding motif protein 39 | 0.0234735 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0233689 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0233629 |
| TFG | TRK-fused gene | 0.0229255 |
| TOP1 | topoisomerase (DNA) I | 0.0227435 |
| WDR43 | WD repeat domain 43 | 0.0225783 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0224008 |
| SNX13 | sorting nexin 13 | 0.0220678 |
| AHR | aryl hydrocarbon receptor | 0.0216207 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0214151 |
| PTK2 | protein tyrosine kinase 2 | 0.0212408 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0212184 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.02115 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0211029 |
| XPO1 | exportin 1 | 0.0208518 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.020826 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0207791 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0207314 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0203262 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0201146 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0200834 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0199759 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0199364 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0198425 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0194451 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0191624 |
| TPD52 | tumor protein D52 | 0.0191161 |
| PI15 | peptidase inhibitor 15 | 0.019033 |
| VCL | vinculin | 0.0189273 |
| FBXO7 | F-box protein 7 | 0.0187256 |
| ZNF638 | zinc finger protein 638 | 0.0185093 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0184206 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0184099 |
| OGA | O-GlcNAcase | 0.0183095 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0180721 |
| WDR45B | WD repeat domain 45B | 0.0180589 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0179648 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0178672 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0177765 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0176856 |
| SETBP1 | SET binding protein 1 | 0.0176539 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0175016 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0173306 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0173056 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0172362 |
| RHEB | Ras homolog enriched in brain | 0.0170723 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0170571 |
| CCNL1 | cyclin L1 | 0.0170495 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0170308 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0168863 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.016864 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.016863 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0168584 |
| EP300 | E1A binding protein p300 | 0.0168227 |
| XPO6 | exportin 6 | 0.0167597 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0166723 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.016591 |
| FOXJ3 | forkhead box J3 | 0.0164638 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0164404 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0164034 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0163198 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.508908 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262352 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.22193 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123758 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.110383 |
| VGF | VGF nerve growth factor inducible | -0.105111 |
| TNNC1 | troponin C type 1 (slow) | -0.102502 |
| VIM | vimentin | -0.0782558 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0735913 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0709251 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0618364 |
| GPC6 | glypican 6 | -0.0607177 |
| FRMD4A | FERM domain containing 4A | -0.0606111 |
| HMCN1 | hemicentin 1 | -0.0520639 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0494932 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.046354 |
| MACROD2 | MACRO domain containing 2 | -0.0455209 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0447405 |
| TAGLN2 | transgelin 2 | -0.0444594 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0440653 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0439797 |
| ICAM1 | intercellular adhesion molecule 1 | -0.043823 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0419866 |
| TMSB10 | thymosin beta 10 | -0.039938 |
| PDE10A | phosphodiesterase 10A | -0.0397644 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0390559 |
| A2M | alpha-2-macroglobulin | -0.0380246 |
| AHNAK | AHNAK nucleoprotein | -0.0374205 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0369399 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0368471 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0361453 |
| ACTG1 | actin gamma 1 | -0.035287 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0343773 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0340949 |
| IER3 | immediate early response 3 | -0.0340851 |
| MT2A | metallothionein 2A | -0.0330772 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324135 |
| S100A6 | S100 calcium binding protein A6 | -0.0316563 |
| SFTPA2 | surfactant protein A2 | -0.0315271 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313395 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0306431 |
| PCDH7 | protocadherin 7 | -0.0301901 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0298794 |
| OSMR | oncostatin M receptor | -0.0297844 |
| NAV3 | neuron navigator 3 | -0.0293064 |
| EXOC4 | exocyst complex component 4 | -0.0290735 |
| CDK14 | cyclin-dependent kinase 14 | -0.0288719 |
| LDHA | lactate dehydrogenase A | -0.0286669 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0282533 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0271746 |
| NHSL1 | NHS-like 1 | -0.0262828 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0261354 |
| GNAS | GNAS complex locus | -0.0258444 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0248354 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0246793 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0240721 |
| FRMD5 | FERM domain containing 5 | -0.0238836 |
| RUNX1 | runt-related transcription factor 1 | -0.0237869 |
| LAMB1 | laminin, beta 1 | -0.0237799 |
| NRCAM | neuronal cell adhesion molecule | -0.0234051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0233397 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232665 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0232382 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0231477 |
| ENO1 | enolase 1, (alpha) | -0.023057 |
| FBXO32 | F-box protein 32 | -0.0230424 |
| FHIT | fragile histidine triad | -0.0227611 |
| RPL35A | ribosomal protein L35a | -0.0226814 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0225581 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0223973 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0221954 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221601 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0221038 |
| CD63 | CD63 molecule | -0.0220862 |
| HMGA2 | high mobility group AT-hook 2 | -0.0219007 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0218947 |
| CD44 | CD44 molecule (Indian blood group) | -0.0217514 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0216351 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0215184 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0214802 |
| NBEA | neurobeachin | -0.021316 |
| DCT | dopachrome tautomerase | -0.0207455 |
| EHBP1 | EH domain binding protein 1 | -0.0206311 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0205969 |
| MITF | microphthalmia-associated transcription factor | -0.0202886 |
| COL1A2 | collagen, type I, alpha 2 | -0.0202732 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0201673 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0199251 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0199163 |
| GSN | gelsolin | -0.0196298 |
| RRBP1 | ribosome binding protein 1 | -0.0195613 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0194013 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0191768 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0191121 |
| SDC2 | syndecan 2 | -0.0191042 |
| RPLP0 | ribosomal protein, large, P0 | -0.0191016 |
| LSAMP | limbic system-associated membrane protein | -0.0190934 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0190721 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0188936 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0184107 |
