| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.207174 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.150558 |
| TMSB4X | thymosin beta 4, X-linked | 0.145211 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0927832 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.082065 |
| DTNA | dystrobrevin, alpha | 0.0754746 |
| EZR | ezrin | 0.0664521 |
| CCNY | cyclin Y | 0.0662199 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0662178 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.064568 |
| FAM13A | family with sequence similarity 13, member A | 0.0642696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0597253 |
| CP | ceruloplasmin (ferroxidase) | 0.0583833 |
| LMO7 | LIM domain 7 | 0.0565327 |
| OGA | O-GlcNAcase | 0.0563325 |
| MEF2A | myocyte enhancer factor 2A | 0.0550983 |
| PGK1 | phosphoglycerate kinase 1 | 0.0546875 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0506073 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0501307 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.049386 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0493346 |
| COPA | coatomer protein complex, subunit alpha | 0.0491142 |
| LAMB3 | laminin, beta 3 | 0.0469831 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0451844 |
| MMP7 | matrix metallopeptidase 7 | 0.0410867 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0407741 |
| VIM | vimentin | 0.0402246 |
| PARD3 | par-3 family cell polarity regulator | 0.0396852 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0394112 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0394105 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0393341 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0388156 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0384061 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0378214 |
| TMSB10 | thymosin beta 10 | 0.0377453 |
| MCU | mitochondrial calcium uniporter | 0.037336 |
| HELZ | helicase with zinc finger | 0.0370891 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0369349 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0346227 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0345016 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.034439 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.034326 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0342981 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0341982 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0339207 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0332918 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0331375 |
| SUCO | SUN domain containing ossification factor | 0.0327078 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0320429 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0319691 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0316784 |
| TFG | TRK-fused gene | 0.0311301 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0310985 |
| FLNB | filamin B, beta | 0.0309038 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0308566 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.030448 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0301517 |
| KRT8 | keratin 8, type II | 0.0299396 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0297681 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0297357 |
| FMNL2 | formin-like 2 | 0.0289765 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0289677 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0287017 |
| RAI1 | retinoic acid induced 1 | 0.0284942 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0282611 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0281769 |
| NGLY1 | N-glycanase 1 | 0.0279868 |
| GOLGA4 | golgin A4 | 0.0277277 |
| ZNF292 | zinc finger protein 292 | 0.0274372 |
| SDC4 | syndecan 4 | 0.0274174 |
| PLS3 | plastin 3 | 0.0271101 |
| NCKAP5 | NCK-associated protein 5 | 0.0270699 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0268627 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0267307 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0265012 |
| FNBP1L | formin binding protein 1-like | 0.0264598 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0262005 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0261688 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026066 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0260112 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0258665 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0256666 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0253035 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0250635 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0247301 |
| CALR | calreticulin | 0.0246345 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0244529 |
| CCDC47 | coiled-coil domain containing 47 | 0.0242841 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0242729 |
| ENO1 | enolase 1, (alpha) | 0.0242301 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0241663 |
| KIAA1671 | KIAA1671 | 0.0241343 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0235047 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0232479 |
| RBM39 | RNA binding motif protein 39 | 0.0232341 |
| FAM162A | family with sequence similarity 162, member A | 0.0231287 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0231144 |
| CMIP | c-Maf inducing protein | 0.0228004 |
| FOXO3 | forkhead box O3 | 0.0225086 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0224574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22279 |
| MT2A | metallothionein 2A | -0.163255 |
| NDRG1 | N-myc downstream regulated 1 | -0.140983 |
| FNDC3B | fibronectin type III domain containing 3B | -0.122168 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0996967 |
| HMGA1 | high mobility group AT-hook 1 | -0.0958329 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0956747 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0841141 |
| ASPH | aspartate beta-hydroxylase | -0.0799073 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0774497 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.077322 |
| POTEF | POTE ankyrin domain family, member F | -0.0766935 |
| KRT19 | keratin 19, type I | -0.0731038 |
| CDCP1 | CUB domain containing protein 1 | -0.0724057 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0708827 |
| ACTG1 | actin gamma 1 | -0.0656711 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0652504 |
| SMAD3 | SMAD family member 3 | -0.0612845 |
| RPL11 | ribosomal protein L11 | -0.0587702 |
| FAM3C | family with sequence similarity 3, member C | -0.0574473 |
| TGM2 | transglutaminase 2 | -0.0559542 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0558197 |
| TPM1 | tropomyosin 1 (alpha) | -0.0553064 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0538678 |
| RPL23 | ribosomal protein L23 | -0.0520288 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0518633 |
| RPS2 | ribosomal protein S2 | -0.0496137 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0492217 |
| RPLP1 | ribosomal protein, large, P1 | -0.0490818 |
| OSMR | oncostatin M receptor | -0.0481068 |
| DSG2 | desmoglein 2 | -0.0478215 |
| RNF213 | ring finger protein 213 | -0.0474822 |
| EFNA5 | ephrin-A5 | -0.0472448 |
| MX1 | MX dynamin-like GTPase 1 | -0.0469936 |
| RPL9 | ribosomal protein L9 | -0.0466689 |
| UBC | ubiquitin C | -0.0457361 |
| CCNL1 | cyclin L1 | -0.0455286 |
| TXNIP | thioredoxin interacting protein | -0.0453893 |
| EGR1 | early growth response 1 | -0.0448964 |
| LAMA4 | laminin, alpha 4 | -0.044428 |
| RPLP0 | ribosomal protein, large, P0 | -0.0444102 |
| NRP1 | neuropilin 1 | -0.0435969 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0418202 |
| BICC1 | BicC family RNA binding protein 1 | -0.0411225 |
| MAP1B | microtubule-associated protein 1B | -0.0410263 |
| KIAA1217 | KIAA1217 | -0.0409481 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0404132 |
| LAMB1 | laminin, beta 1 | -0.0402772 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0401592 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0399065 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0397995 |
| LAMC2 | laminin, gamma 2 | -0.0395208 |
| BRD2 | bromodomain containing 2 | -0.0388473 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0386938 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0384824 |
| KLF6 | Kruppel-like factor 6 | -0.0384737 |
| MYOF | myoferlin | -0.0381981 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0378224 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0374776 |
| RPL19 | ribosomal protein L19 | -0.0366728 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.036649 |
| DST | dystonin | -0.0359486 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0354895 |
| MUC4 | mucin 4, cell surface associated | -0.0354355 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0353842 |
| SLTM | SAFB-like, transcription modulator | -0.0348073 |
| PKM | pyruvate kinase, muscle | -0.0345585 |
| CLTC | clathrin, heavy chain (Hc) | -0.033585 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0331424 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0322168 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0321567 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0320275 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0315806 |
| RTN4 | reticulon 4 | -0.031273 |
| DPYD | dihydropyrimidine dehydrogenase | -0.030401 |
| RUNX1 | runt-related transcription factor 1 | -0.0303864 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0303305 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0301759 |
| ACTN1 | actinin, alpha 1 | -0.0301486 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0301224 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0299785 |
| DUSP5 | dual specificity phosphatase 5 | -0.029684 |
| RPS8 | ribosomal protein S8 | -0.0295638 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0293941 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0291528 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0288505 |
| SMYD3 | SET and MYND domain containing 3 | -0.0287178 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0286496 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0285218 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0283802 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0283708 |
| NOTCH2 | notch 2 | -0.0282642 |
| TAGLN2 | transgelin 2 | -0.0281602 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0279846 |
| RPS23 | ribosomal protein S23 | -0.0279149 |
| PEG10 | paternally expressed 10 | -0.0277823 |
| ANO6 | anoctamin 6 | -0.0276229 |
| DSTN | destrin (actin depolymerizing factor) | -0.0275968 |
| AREG | amphiregulin | -0.0274787 |
| MYADM | myeloid-associated differentiation marker | -0.0272615 |
