| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.191097 |
| GOLGA4 | golgin A4 | 0.0798629 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.076073 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0614062 |
| OGA | O-GlcNAcase | 0.0612889 |
| PRELID2 | PRELI domain containing 2 | 0.060875 |
| ARF4 | ADP-ribosylation factor 4 | 0.058289 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0570636 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0556444 |
| HELZ | helicase with zinc finger | 0.0535863 |
| SUCO | SUN domain containing ossification factor | 0.0525443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0524984 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0517719 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0482774 |
| YEATS2 | YEATS domain containing 2 | 0.048098 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0476858 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0466055 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.046062 |
| FAM117B | family with sequence similarity 117, member B | 0.0455641 |
| RUNX1 | runt-related transcription factor 1 | 0.0450872 |
| INSIG2 | insulin induced gene 2 | 0.0447825 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0439684 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.042907 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0428027 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0421727 |
| ZNF292 | zinc finger protein 292 | 0.0409444 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0407177 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0403948 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0403679 |
| WDR45B | WD repeat domain 45B | 0.0401712 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0399019 |
| COG6 | component of oligomeric golgi complex 6 | 0.0397179 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0395081 |
| NUP58 | nucleoporin 58 | 0.0392977 |
| ARFGEF3 | ARFGEF family member 3 | 0.0389153 |
| POM121 | POM121 transmembrane nucleoporin | 0.0380451 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0378927 |
| ZNF654 | zinc finger protein 654 | 0.037729 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0374307 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0369346 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0366111 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0364278 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0360715 |
| WDR26 | WD repeat domain 26 | 0.0358268 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0355269 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0354516 |
| TMEM41B | transmembrane protein 41B | 0.0354135 |
| RNF24 | ring finger protein 24 | 0.0351747 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0350896 |
| B2M | beta-2-microglobulin | 0.0350513 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0350154 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0347998 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.034046 |
| SRP54 | signal recognition particle 54kDa | 0.0338522 |
| RAB18 | RAB18, member RAS oncogene family | 0.0337355 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0336125 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0335392 |
| COPA | coatomer protein complex, subunit alpha | 0.0334462 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0322729 |
| NBAS | neuroblastoma amplified sequence | 0.032197 |
| MCL1 | myeloid cell leukemia 1 | 0.0321798 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0320106 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.031685 |
| MT2A | metallothionein 2A | 0.031636 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0314776 |
| YTHDC1 | YTH domain containing 1 | 0.0311899 |
| FNIP1 | folliculin interacting protein 1 | 0.0308086 |
| USP34 | ubiquitin specific peptidase 34 | 0.0302862 |
| KIAA1217 | KIAA1217 | 0.0301775 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0301098 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0301016 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0301016 |
| TMF1 | TATA element modulatory factor 1 | 0.0300272 |
| BRD2 | bromodomain containing 2 | 0.0299841 |
| SPAG9 | sperm associated antigen 9 | 0.029192 |
| TMEM39A | transmembrane protein 39A | 0.0289914 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0288117 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0287887 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0286735 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286637 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0285896 |
| ZNF638 | zinc finger protein 638 | 0.0282858 |
| TPR | translocated promoter region, nuclear basket protein | 0.0277968 |
| CCDC186 | coiled-coil domain containing 186 | 0.0269225 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0269178 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0267939 |
| CDK19 | cyclin-dependent kinase 19 | 0.0267177 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0265053 |
| RIOK3 | RIO kinase 3 | 0.0262637 |
| USP37 | ubiquitin specific peptidase 37 | 0.0261045 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0256831 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0254136 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0254074 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252336 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0252213 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0249935 |
| RBM39 | RNA binding motif protein 39 | 0.0249385 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.024937 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0248047 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0245478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.372858 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.179916 |
| AHNAK | AHNAK nucleoprotein | -0.153535 |
| TENM3 | teneurin transmembrane protein 3 | -0.0925128 |
| PTMA | prothymosin, alpha | -0.0765786 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0692807 |
| MSI2 | musashi RNA-binding protein 2 | -0.0665897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0664774 |
| KRT18 | keratin 18, type I | -0.0648739 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0631305 |
| POTEF | POTE ankyrin domain family, member F | -0.062196 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0589828 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0581761 |
| MED13L | mediator complex subunit 13-like | -0.0557094 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0526939 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0520533 |
| MKI67 | marker of proliferation Ki-67 | -0.0506976 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0506058 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.050029 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0496008 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0494282 |
| CANX | calnexin | -0.0488785 |
| SERINC5 | serine incorporator 5 | -0.0486162 |
| RAD51B | RAD51 paralog B | -0.0482198 |
| EXOC4 | exocyst complex component 4 | -0.0467104 |
| TCF12 | transcription factor 12 | -0.0466513 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0457346 |
| ZNRF3 | zinc and ring finger 3 | -0.0457144 |
| TMSB10 | thymosin beta 10 | -0.0439287 |
| FRMD5 | FERM domain containing 5 | -0.043806 |
| RNF213 | ring finger protein 213 | -0.0436918 |
| PKM | pyruvate kinase, muscle | -0.0434182 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0427067 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0423475 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.041987 |
| CCND1 | cyclin D1 | -0.0419395 |
| RNF43 | ring finger protein 43 | -0.0397914 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0395303 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0383173 |
| EHBP1 | EH domain binding protein 1 | -0.0379019 |
| ENO1 | enolase 1, (alpha) | -0.0378798 |
| CADPS | Ca++-dependent secretion activator | -0.0376066 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0375161 |
| SHROOM3 | shroom family member 3 | -0.0373791 |
| NFIA | nuclear factor I/A | -0.0372159 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0366222 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0359342 |
| LDHA | lactate dehydrogenase A | -0.0357979 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0357225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0355946 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.035279 |
| WWOX | WW domain containing oxidoreductase | -0.0351374 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0349551 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0348506 |
| ACTG1 | actin gamma 1 | -0.0343274 |
| RPL35A | ribosomal protein L35a | -0.0336541 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0336453 |
| RPS24 | ribosomal protein S24 | -0.0334204 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0332552 |
| ARF1 | ADP-ribosylation factor 1 | -0.0331082 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0328506 |
| TMEM123 | transmembrane protein 123 | -0.032562 |
| HMGA2 | high mobility group AT-hook 2 | -0.0318836 |
| CUX1 | cut-like homeobox 1 | -0.0315637 |
| TUBA1B | tubulin, alpha 1b | -0.031413 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0313602 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0313372 |
| RBM47 | RNA binding motif protein 47 | -0.0308929 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.030861 |
| FHIT | fragile histidine triad | -0.030489 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0304106 |
| DIAPH2 | diaphanous-related formin 2 | -0.03039 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0303456 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302049 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0298367 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0297959 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0297664 |
| CLOCK | clock circadian regulator | -0.0295709 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.029566 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.029116 |
| SATB2 | SATB homeobox 2 | -0.0287863 |
| KRT19 | keratin 19, type I | -0.0284678 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0283725 |
| SUMF1 | sulfatase modifying factor 1 | -0.0280628 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0277881 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0276747 |
| KLF12 | Kruppel-like factor 12 | -0.0275246 |
| HMGA1 | high mobility group AT-hook 1 | -0.0274602 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.0273992 |
| TPI1 | triosephosphate isomerase 1 | -0.0270711 |
| RPS6 | ribosomal protein S6 | -0.0270664 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0270258 |
| MTAP | methylthioadenosine phosphorylase | -0.0269667 |
| TUBB | tubulin, beta class I | -0.0268643 |
| FLNB | filamin B, beta | -0.0266713 |
| VCL | vinculin | -0.0264634 |
| EPCAM | epithelial cell adhesion molecule | -0.0262431 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0261894 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.02618 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0261578 |
