| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| OGA | O-GlcNAcase | 0.0762057 |
| VCL | vinculin | 0.0544794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0518207 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0467571 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0439361 |
| PRELID2 | PRELI domain containing 2 | 0.0411431 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0369301 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0359515 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0337985 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0314317 |
| APP | amyloid beta (A4) precursor protein | 0.0309409 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0298135 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0294912 |
| TMSB4X | thymosin beta 4, X-linked | 0.028232 |
| B2M | beta-2-microglobulin | 0.0282048 |
| CUL3 | cullin 3 | 0.0275357 |
| RTN4 | reticulon 4 | 0.0265623 |
| UBQLN1 | ubiquilin 1 | 0.0250369 |
| RPL14 | ribosomal protein L14 | 0.0249271 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.024885 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243869 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0240447 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0237369 |
| PHF3 | PHD finger protein 3 | 0.0226617 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0225168 |
| FUS | FUS RNA binding protein | 0.0218826 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216438 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0216401 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0207702 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0206911 |
| LAMC2 | laminin, gamma 2 | 0.020394 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0196596 |
| XPO1 | exportin 1 | 0.0194039 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0194012 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.018969 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0187878 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0185775 |
| CEP95 | centrosomal protein 95kDa | 0.0185536 |
| MATR3 | matrin 3 | 0.0185101 |
| RYK | receptor-like tyrosine kinase | 0.0185081 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0184991 |
| QKI | QKI, KH domain containing, RNA binding | 0.0182304 |
| USP53 | ubiquitin specific peptidase 53 | 0.0180603 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0180144 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0178953 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0178187 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0177744 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0177575 |
| SDC4 | syndecan 4 | 0.0177268 |
| RASA2 | RAS p21 protein activator 2 | 0.0176481 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0174568 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0174182 |
| CORO1C | coronin, actin binding protein, 1C | 0.0173516 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0170493 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0169076 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0168371 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0168324 |
| NEK7 | NIMA-related kinase 7 | 0.0167332 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.016697 |
| TJP1 | tight junction protein 1 | 0.0165734 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0165136 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0164723 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.016449 |
| FAM13B | family with sequence similarity 13, member B | 0.0164187 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0164098 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0163906 |
| RASA3 | RAS p21 protein activator 3 | 0.0159282 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0158886 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0156315 |
| GPATCH8 | G patch domain containing 8 | 0.0155942 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0155552 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0155045 |
| AFDN | afadin, adherens junction formation factor | 0.0153683 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0153281 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0153248 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151845 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0151786 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0151292 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0150508 |
| TMEM41B | transmembrane protein 41B | 0.0148862 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0148356 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0147979 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0147618 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0146573 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0146387 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0146112 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0144822 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0144509 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0144356 |
| NUP54 | nucleoporin 54kDa | 0.0143824 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0143495 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0143208 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0142745 |
| TMEM245 | transmembrane protein 245 | 0.0142705 |
| WDR43 | WD repeat domain 43 | 0.0141724 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0141277 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0140395 |
| DMXL1 | Dmx-like 1 | 0.0140032 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0139738 |
| WWC1 | WW and C2 domain containing 1 | 0.0139257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181299 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.12843 |
| NDRG1 | N-myc downstream regulated 1 | -0.118833 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.118314 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104873 |
| LDHA | lactate dehydrogenase A | -0.101641 |
| POTEF | POTE ankyrin domain family, member F | -0.0904917 |
| HMGA1 | high mobility group AT-hook 1 | -0.0870408 |
| PKM | pyruvate kinase, muscle | -0.0769588 |
| FTL | ferritin, light polypeptide | -0.071507 |
| KRT7 | keratin 7, type II | -0.0712901 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0712819 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.068057 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0675102 |
| SVIL | supervillin | -0.066521 |
| ENO1 | enolase 1, (alpha) | -0.0647624 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0644025 |
| ANXA1 | annexin A1 | -0.062598 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0624008 |
| EGFR | epidermal growth factor receptor | -0.0605357 |
| BPTF | bromodomain PHD finger transcription factor | -0.0600877 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0584245 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0578852 |
| CCND1 | cyclin D1 | -0.0571952 |
| EGR1 | early growth response 1 | -0.0558358 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0548735 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0541215 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0535453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0528672 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0525621 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0522909 |
| ANXA2 | annexin A2 | -0.0510105 |
| TMSB10 | thymosin beta 10 | -0.0479893 |
| TPM4 | tropomyosin 4 | -0.0468376 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0456421 |
| ACTG1 | actin gamma 1 | -0.0454939 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0441139 |
| TXNRD1 | thioredoxin reductase 1 | -0.0421894 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0421223 |
| MT2A | metallothionein 2A | -0.041475 |
| RPL28 | ribosomal protein L28 | -0.0410436 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0405349 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0402013 |
| ASPH | aspartate beta-hydroxylase | -0.0399226 |
| TPI1 | triosephosphate isomerase 1 | -0.0394808 |
| HMGA2 | high mobility group AT-hook 2 | -0.0391445 |
| RPS6 | ribosomal protein S6 | -0.0388613 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0387712 |
| CALR | calreticulin | -0.0372528 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0368944 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0367072 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0364221 |
| FLNB | filamin B, beta | -0.0363501 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0358501 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0340136 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0330332 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0328862 |
| VCAN | versican | -0.0326235 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0326192 |
| MYADM | myeloid-associated differentiation marker | -0.0325869 |
| RNF213 | ring finger protein 213 | -0.0324004 |
| PLCB4 | phospholipase C, beta 4 | -0.0323001 |
| MAP4 | microtubule-associated protein 4 | -0.0320862 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0317702 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0316119 |
| KRT19 | keratin 19, type I | -0.0299709 |
| DSTN | destrin (actin depolymerizing factor) | -0.0296142 |
| PFN1 | profilin 1 | -0.0295334 |
| UTRN | utrophin | -0.0294918 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0292551 |
| RPL19 | ribosomal protein L19 | -0.0291375 |
| WASF2 | WAS protein family, member 2 | -0.0286398 |
| RUNX1 | runt-related transcription factor 1 | -0.0285834 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0284831 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0283013 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0282879 |
| S100A6 | S100 calcium binding protein A6 | -0.028195 |
| MKI67 | marker of proliferation Ki-67 | -0.0281053 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0279209 |
| CENPF | centromere protein F, 350/400kDa | -0.0274596 |
| CTBP2 | C-terminal binding protein 2 | -0.0273737 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0272199 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0269978 |
| SEPTIN9 | septin 9 | -0.0268095 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0267201 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261571 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0260047 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0259154 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.025909 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0255304 |
| CANX | calnexin | -0.0253785 |
| GOLGA4 | golgin A4 | -0.0252293 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0250698 |
| VDAC1 | voltage-dependent anion channel 1 | -0.024545 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0242553 |
| GNAS | GNAS complex locus | -0.024163 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0239881 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0238606 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0237408 |
| CD44 | CD44 molecule (Indian blood group) | -0.0235077 |
