| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.215007 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.158184 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0948171 |
| RTN4 | reticulon 4 | 0.0849692 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0660928 |
| VCL | vinculin | 0.061369 |
| SPAG9 | sperm associated antigen 9 | 0.0593527 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0590356 |
| RNF145 | ring finger protein 145 | 0.0564373 |
| NUP58 | nucleoporin 58 | 0.0542088 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0521318 |
| ZNF292 | zinc finger protein 292 | 0.051897 |
| MT2A | metallothionein 2A | 0.05043 |
| USP3 | ubiquitin specific peptidase 3 | 0.0502509 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0501663 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0459889 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0457823 |
| EGR1 | early growth response 1 | 0.0446354 |
| RLF | rearranged L-myc fusion | 0.0445948 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0425101 |
| OGA | O-GlcNAcase | 0.0411923 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0403471 |
| RBM39 | RNA binding motif protein 39 | 0.040248 |
| PTMA | prothymosin, alpha | 0.0402432 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0400853 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.039732 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0394081 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0393842 |
| CAPRIN2 | caprin family member 2 | 0.039245 |
| FAM13A | family with sequence similarity 13, member A | 0.0384175 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0369687 |
| TFG | TRK-fused gene | 0.0369626 |
| QKI | QKI, KH domain containing, RNA binding | 0.0367247 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0365694 |
| ATP13A3 | ATPase type 13A3 | 0.0360866 |
| SETD5 | SET domain containing 5 | 0.0355492 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0355417 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.035534 |
| CLIC4 | chloride intracellular channel 4 | 0.035325 |
| WDR45B | WD repeat domain 45B | 0.0338736 |
| MSN | moesin | 0.0338561 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333095 |
| FAM162A | family with sequence similarity 162, member A | 0.0329479 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0328749 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0326294 |
| CORO1C | coronin, actin binding protein, 1C | 0.0324542 |
| MATR3 | matrin 3 | 0.0323204 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0323116 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0322527 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0321975 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0321469 |
| VMP1 | vacuole membrane protein 1 | 0.0320511 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0319671 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0319159 |
| HPCAL1 | hippocalcin-like 1 | 0.0317174 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0314904 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0313414 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0313021 |
| NPTN | neuroplastin | 0.030883 |
| RASA3 | RAS p21 protein activator 3 | 0.0304773 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0304327 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0298387 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0297129 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0295733 |
| IER3 | immediate early response 3 | 0.029408 |
| CCNL1 | cyclin L1 | 0.0294079 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0292993 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0292959 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0291711 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0290893 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0288317 |
| MT1X | metallothionein 1X | 0.0288267 |
| RYBP | RING1 and YY1 binding protein | 0.0283163 |
| SUCO | SUN domain containing ossification factor | 0.0282924 |
| B2M | beta-2-microglobulin | 0.0279965 |
| RASA2 | RAS p21 protein activator 2 | 0.0278181 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0275357 |
| ACTN1 | actinin, alpha 1 | 0.0274933 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0272014 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.027134 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0271236 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0264054 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0262994 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0260011 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0259388 |
| PUM2 | pumilio RNA-binding family member 2 | 0.025934 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0252286 |
| SEPTIN7 | septin 7 | 0.0252237 |
| PGK1 | phosphoglycerate kinase 1 | 0.025131 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0249157 |
| FOXJ3 | forkhead box J3 | 0.0244899 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0243453 |
| TOP1 | topoisomerase (DNA) I | 0.0242438 |
| CD109 | CD109 molecule | 0.0242094 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0241815 |
| HELZ | helicase with zinc finger | 0.0239954 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0236091 |
| TSC22D2 | TSC22 domain family, member 2 | 0.023532 |
| TFRC | transferrin receptor | 0.023526 |
| TUBB6 | tubulin, beta 6 class V | 0.0235046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | -0.164211 |
| FN1 | fibronectin 1 | -0.160179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.146058 |
| VIM | vimentin | -0.144091 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.136761 |
| CDH13 | cadherin 13 | -0.125563 |
| COL5A1 | collagen, type V, alpha 1 | -0.12197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103379 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0860297 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0843498 |
| NAV1 | neuron navigator 1 | -0.0771457 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0742613 |
| IGF2 | insulin-like growth factor 2 | -0.0710139 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0704083 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.069644 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0677531 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0677363 |
| ASPH | aspartate beta-hydroxylase | -0.0622128 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0587374 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0539272 |
| ATXN1 | ataxin 1 | -0.0526147 |
| LAMB3 | laminin, beta 3 | -0.0522496 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0522127 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.052208 |
| ACTG1 | actin gamma 1 | -0.0515339 |
| FMN1 | formin 1 | -0.0503221 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0494991 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0485139 |
| RAI14 | retinoic acid induced 14 | -0.0462334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0460279 |
| RPLP1 | ribosomal protein, large, P1 | -0.045729 |
| DTNA | dystrobrevin, alpha | -0.0457147 |
| RPS6 | ribosomal protein S6 | -0.0451863 |
| ENO1 | enolase 1, (alpha) | -0.0436578 |
| PRELID2 | PRELI domain containing 2 | -0.043206 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0427427 |
| FRMD4A | FERM domain containing 4A | -0.0426698 |
| NAV2 | neuron navigator 2 | -0.0426672 |
| GOLGB1 | golgin B1 | -0.0417223 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0394746 |
| DIAPH2 | diaphanous-related formin 2 | -0.0394068 |
| AHNAK | AHNAK nucleoprotein | -0.0375561 |
| RPS8 | ribosomal protein S8 | -0.0366441 |
| CCND1 | cyclin D1 | -0.0362302 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0354443 |
| COL6A3 | collagen, type VI, alpha 3 | -0.034965 |
| RPL9 | ribosomal protein L9 | -0.0348505 |
| FNIP1 | folliculin interacting protein 1 | -0.0347153 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0344687 |
| PCBP3 | poly(rC) binding protein 3 | -0.0339803 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0335585 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0332993 |
| DST | dystonin | -0.0322194 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0322135 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0319731 |
| HM13 | histocompatibility (minor) 13 | -0.0319188 |
| EGFR | epidermal growth factor receptor | -0.0313168 |
| RPL12 | ribosomal protein L12 | -0.0312078 |
| EFNA5 | ephrin-A5 | -0.030961 |
| MYO9A | myosin IXA | -0.030612 |
| MORF4L2 | mortality factor 4 like 2 | -0.0303006 |
| RAD51B | RAD51 paralog B | -0.030173 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0301314 |
| NDRG1 | N-myc downstream regulated 1 | -0.0293118 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.029012 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.028927 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0287616 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0286377 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0284528 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0278957 |
| PDE10A | phosphodiesterase 10A | -0.0278805 |
| MMP12 | matrix metallopeptidase 12 | -0.0276103 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0272746 |
| INTS6 | integrator complex subunit 6 | -0.0272447 |
| MYO10 | myosin X | -0.0268326 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0266613 |
| SEPTIN2 | septin 2 | -0.0265247 |
| CFAP20DC | CFAP20 domain containing | -0.0263934 |
| EHBP1 | EH domain binding protein 1 | -0.0260003 |
| HMGA1 | high mobility group AT-hook 1 | -0.0259476 |
| ANXA2 | annexin A2 | -0.0258853 |
| RPL35A | ribosomal protein L35a | -0.025523 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0252775 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0251917 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0246671 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0239872 |
| RPS24 | ribosomal protein S24 | -0.0239394 |
| SQSTM1 | sequestosome 1 | -0.0237878 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0236994 |
| BPTF | bromodomain PHD finger transcription factor | -0.0235616 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0232757 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0232465 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0229484 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0228561 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0227782 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0225419 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225341 |
| RIN2 | Ras and Rab interactor 2 | -0.0224845 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0223621 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0223176 |
