| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.17858 |
| COL6A3 | collagen, type VI, alpha 3 | 0.16852 |
| ATP13A3 | ATPase type 13A3 | 0.139126 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.122403 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0963047 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0929444 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0906099 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0731669 |
| TFG | TRK-fused gene | 0.0683691 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0653784 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0611571 |
| SPAG9 | sperm associated antigen 9 | 0.0608585 |
| RASA2 | RAS p21 protein activator 2 | 0.060453 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0599399 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0595839 |
| TMSB4X | thymosin beta 4, X-linked | 0.0563921 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0563877 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0563193 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0552322 |
| PDE10A | phosphodiesterase 10A | 0.0525723 |
| ZNF292 | zinc finger protein 292 | 0.0518605 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0511049 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0491497 |
| APP | amyloid beta (A4) precursor protein | 0.0474299 |
| RLF | rearranged L-myc fusion | 0.0474163 |
| FMNL2 | formin-like 2 | 0.0468381 |
| PTK2 | protein tyrosine kinase 2 | 0.0464384 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463736 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0461903 |
| B2M | beta-2-microglobulin | 0.0460229 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0446831 |
| CADM1 | cell adhesion molecule 1 | 0.0431744 |
| CALR | calreticulin | 0.0426988 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0424063 |
| COL5A1 | collagen, type V, alpha 1 | 0.0411128 |
| MRTFA | myocardin related transcription factor A | 0.0409472 |
| RBM39 | RNA binding motif protein 39 | 0.0406368 |
| CANX | calnexin | 0.0401263 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0399711 |
| SUCO | SUN domain containing ossification factor | 0.0396493 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0391388 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0385585 |
| TPM4 | tropomyosin 4 | 0.0384169 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0383174 |
| OGA | O-GlcNAcase | 0.0383093 |
| HIP1 | huntingtin interacting protein 1 | 0.0376145 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0375562 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0366321 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0361723 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0354957 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0342079 |
| SDC4 | syndecan 4 | 0.0338251 |
| COPA | coatomer protein complex, subunit alpha | 0.0330696 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.032834 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0327557 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0326585 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0324456 |
| CAVIN1 | caveolae associated protein 1 | 0.032416 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0324024 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0322794 |
| EXT1 | exostosin glycosyltransferase 1 | 0.031711 |
| ARRDC3 | arrestin domain containing 3 | 0.0316141 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0315819 |
| FOXJ3 | forkhead box J3 | 0.0314148 |
| DENND5A | DENN/MADD domain containing 5A | 0.0313009 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0311032 |
| CCNY | cyclin Y | 0.0306396 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0306129 |
| USP3 | ubiquitin specific peptidase 3 | 0.030516 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0300666 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0298307 |
| RYBP | RING1 and YY1 binding protein | 0.0297222 |
| QKI | QKI, KH domain containing, RNA binding | 0.0296521 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0295593 |
| CD109 | CD109 molecule | 0.0295407 |
| SMAD3 | SMAD family member 3 | 0.0294145 |
| RHEB | Ras homolog enriched in brain | 0.0292207 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0292153 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0286858 |
| HELZ | helicase with zinc finger | 0.0286671 |
| ANXA1 | annexin A1 | 0.0283973 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0283923 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0283713 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0281835 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0281009 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0280788 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0277852 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0277718 |
| GOLGA4 | golgin A4 | 0.0274124 |
| SDC2 | syndecan 2 | 0.0272279 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0272059 |
| MED13L | mediator complex subunit 13-like | 0.0272032 |
| TMEM39A | transmembrane protein 39A | 0.0265723 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0264549 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0262276 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0256411 |
| RYK | receptor-like tyrosine kinase | 0.0255561 |
| CDC73 | cell division cycle 73 | 0.0253625 |
| RPL14 | ribosomal protein L14 | 0.0253491 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0252866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.249456 |
| FN1 | fibronectin 1 | -0.211362 |
| VIM | vimentin | -0.185215 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.179626 |
| MT2A | metallothionein 2A | -0.124532 |
| CD44 | CD44 molecule (Indian blood group) | -0.114732 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.09161 |
| TMSB10 | thymosin beta 10 | -0.0881543 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0837125 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0739227 |
| RPL35A | ribosomal protein L35a | -0.0690665 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0682617 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0653295 |
| FTL | ferritin, light polypeptide | -0.0637697 |
| COL1A1 | collagen, type I, alpha 1 | -0.0620863 |
| NDRG1 | N-myc downstream regulated 1 | -0.0618953 |
| MAP1B | microtubule-associated protein 1B | -0.0608528 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0571223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0553982 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0505618 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0493795 |
| HMGA1 | high mobility group AT-hook 1 | -0.047821 |
| PFN1 | profilin 1 | -0.0465797 |
| POTEF | POTE ankyrin domain family, member F | -0.0459192 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0458503 |
| RPS6 | ribosomal protein S6 | -0.0453191 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0443535 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0440654 |
| HLA-A | major histocompatibility complex, class I, A | -0.0435657 |
| HLA-B | major histocompatibility complex, class I, B | -0.0430983 |
| RPS8 | ribosomal protein S8 | -0.0427605 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.042592 |
| RPLP0 | ribosomal protein, large, P0 | -0.0390717 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0390313 |
| NRP1 | neuropilin 1 | -0.0389098 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0383883 |
| IL6 | interleukin 6 | -0.0377505 |
| HMGA2 | high mobility group AT-hook 2 | -0.037506 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0373985 |
| RPL28 | ribosomal protein L28 | -0.0363385 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0360114 |
| RPLP1 | ribosomal protein, large, P1 | -0.0357068 |
| RPL11 | ribosomal protein L11 | -0.0355741 |
| S100A10 | S100 calcium binding protein A10 | -0.0347815 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0340905 |
| POSTN | periostin, osteoblast specific factor | -0.034009 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0336362 |
| S100A9 | S100 calcium binding protein A9 | -0.0334643 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0332188 |
| RACK1 | receptor for activated C kinase 1 | -0.0331918 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0330039 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0327891 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0326923 |
| RPS19 | ribosomal protein S19 | -0.0322983 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0322124 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0321401 |
| STC1 | stanniocalcin 1 | -0.0316727 |
| ACTG1 | actin gamma 1 | -0.0313811 |
| UBC | ubiquitin C | -0.0312197 |
| RPL30 | ribosomal protein L30 | -0.0310841 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.031006 |
| EGR1 | early growth response 1 | -0.0304815 |
| TAPBP | TAP binding protein (tapasin) | -0.0303769 |
| ASPH | aspartate beta-hydroxylase | -0.0299187 |
| RPL8 | ribosomal protein L8 | -0.0295763 |
| RPL23 | ribosomal protein L23 | -0.029257 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0280511 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.02804 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0280157 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0278715 |
| MX2 | MX dynamin-like GTPase 2 | -0.0273934 |
| RPS11 | ribosomal protein S11 | -0.0273405 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0272694 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0271445 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0270344 |
| RPS14 | ribosomal protein S14 | -0.0265498 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0262584 |
| RPL19 | ribosomal protein L19 | -0.0261205 |
| RPS12 | ribosomal protein S12 | -0.0260478 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0258412 |
| RPS25 | ribosomal protein S25 | -0.0256306 |
| IL6ST | interleukin 6 signal transducer | -0.0254943 |
| MYADM | myeloid-associated differentiation marker | -0.0245588 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0242861 |
| RPS20 | ribosomal protein S20 | -0.0241853 |
| TPI1 | triosephosphate isomerase 1 | -0.0238263 |
| PERP | PERP, TP53 apoptosis effector | -0.0236683 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0235758 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0234556 |
| BSG | basigin (Ok blood group) | -0.0234138 |
| ATL1 | atlastin GTPase 1 | -0.0229595 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0229147 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0222705 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0220553 |
| TAGLN2 | transgelin 2 | -0.022013 |
| RPL9 | ribosomal protein L9 | -0.0219362 |
| RPLP2 | ribosomal protein, large, P2 | -0.0219067 |
| RPS5 | ribosomal protein S5 | -0.0215694 |
| TUBB | tubulin, beta class I | -0.0215306 |
| COL1A2 | collagen, type I, alpha 2 | -0.0213335 |
