| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.143185 |
| B2M | beta-2-microglobulin | 0.105516 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0734462 |
| ZNF841 | zinc finger protein 841 | 0.0580839 |
| DTNA | dystrobrevin, alpha | 0.0543725 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0526655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0510293 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0470922 |
| NAV2 | neuron navigator 2 | 0.0453176 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440961 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0430319 |
| ATP13A3 | ATPase type 13A3 | 0.0429303 |
| TMSB4X | thymosin beta 4, X-linked | 0.0391029 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0375585 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0365844 |
| CANX | calnexin | 0.0359504 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0328611 |
| SUCO | SUN domain containing ossification factor | 0.0328518 |
| NUP58 | nucleoporin 58 | 0.0327645 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319952 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314709 |
| DIPK2A | divergent protein kinase domain 2A | 0.0309841 |
| MMP12 | matrix metallopeptidase 12 | 0.0307281 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0304611 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0298992 |
| PGK1 | phosphoglycerate kinase 1 | 0.0298149 |
| SDC4 | syndecan 4 | 0.0290758 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0287273 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0284352 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0279868 |
| TMEM41B | transmembrane protein 41B | 0.0273061 |
| RYBP | RING1 and YY1 binding protein | 0.026936 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0268075 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0267683 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0267285 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0263252 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0261595 |
| STK4 | serine/threonine kinase 4 | 0.0260774 |
| MSN | moesin | 0.0256522 |
| TPM3 | tropomyosin 3 | 0.0256293 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0255548 |
| VEGFA | vascular endothelial growth factor A | 0.025471 |
| XPO6 | exportin 6 | 0.0250984 |
| FAM219A | family with sequence similarity 219, member A | 0.0250561 |
| SMAD3 | SMAD family member 3 | 0.0241476 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0240323 |
| CRY1 | cryptochrome circadian clock 1 | 0.0235271 |
| DENND5A | DENN/MADD domain containing 5A | 0.0234738 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0231979 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.023104 |
| ARRDC3 | arrestin domain containing 3 | 0.0230406 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0227399 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0225758 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0225283 |
| ANXA1 | annexin A1 | 0.0225148 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0223806 |
| ANLN | anillin, actin binding protein | 0.0223491 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0222275 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.022152 |
| RND3 | Rho family GTPase 3 | 0.0220569 |
| CEP250 | centrosomal protein 250kDa | 0.0216991 |
| FOXO3 | forkhead box O3 | 0.0216764 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0216375 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0216355 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0216322 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0215391 |
| BRD2 | bromodomain containing 2 | 0.0214949 |
| EZR | ezrin | 0.0213943 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0211616 |
| SPAG9 | sperm associated antigen 9 | 0.0209911 |
| ECT2 | epithelial cell transforming 2 | 0.0208725 |
| CALR | calreticulin | 0.0206422 |
| OSBP | oxysterol binding protein | 0.020456 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0204263 |
| FNIP1 | folliculin interacting protein 1 | 0.020367 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0203522 |
| OGA | O-GlcNAcase | 0.0202499 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0198647 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0198068 |
| FAM107B | family with sequence similarity 107, member B | 0.0196491 |
| IRS2 | insulin receptor substrate 2 | 0.0194824 |
| GOLGA4 | golgin A4 | 0.0192958 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0192786 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0192407 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0190625 |
| OPTN | optineurin | 0.0189192 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0189108 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0187337 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0186874 |
| CLIC4 | chloride intracellular channel 4 | 0.0186274 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0185435 |
| CHKA | choline kinase alpha | 0.0184682 |
| ARFGEF3 | ARFGEF family member 3 | 0.0183939 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0182415 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0181917 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0181627 |
| RAB18 | RAB18, member RAS oncogene family | 0.017913 |
| ADM | adrenomedullin | 0.0178708 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0178262 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0178236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.263836 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192361 |
| HLA-B | major histocompatibility complex, class I, B | -0.152341 |
| CD44 | CD44 molecule (Indian blood group) | -0.0898484 |
| TXNRD1 | thioredoxin reductase 1 | -0.0873205 |
| DEK | DEK proto-oncogene | -0.0853813 |
| MT2A | metallothionein 2A | -0.0839195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0800112 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0772051 |
| RPL35A | ribosomal protein L35a | -0.0743665 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733401 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0616754 |
| TUBB | tubulin, beta class I | -0.0588324 |
| EXT1 | exostosin glycosyltransferase 1 | -0.058259 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0580153 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0571105 |
| GLIS3 | GLIS family zinc finger 3 | -0.0560748 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0558617 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0552153 |
| RPS6 | ribosomal protein S6 | -0.0545565 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0545311 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0542521 |
| POTEF | POTE ankyrin domain family, member F | -0.0532987 |
| MAP1B | microtubule-associated protein 1B | -0.0531704 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0527196 |
| PTMA | prothymosin, alpha | -0.0520187 |
| CTSD | cathepsin D | -0.0509214 |
| HMGB1 | high mobility group box 1 | -0.0505635 |
| AHNAK | AHNAK nucleoprotein | -0.0505379 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0502871 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0498594 |
| DIAPH3 | diaphanous-related formin 3 | -0.0493494 |
| TMSB10 | thymosin beta 10 | -0.0462017 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0451381 |
| OSMR | oncostatin M receptor | -0.0437572 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0427426 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0425143 |
| ACTG1 | actin gamma 1 | -0.0424436 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0409932 |
| RPLP2 | ribosomal protein, large, P2 | -0.0409514 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0398473 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0389654 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0382472 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0364458 |
| RPL23 | ribosomal protein L23 | -0.0364078 |
| S100A6 | S100 calcium binding protein A6 | -0.0362429 |
| RPL11 | ribosomal protein L11 | -0.0361716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360234 |
| PFN1 | profilin 1 | -0.0356742 |
| KRT18 | keratin 18, type I | -0.0355199 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0353242 |
| TPI1 | triosephosphate isomerase 1 | -0.0352668 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.034804 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0346912 |
| RPL12 | ribosomal protein L12 | -0.0345734 |
| MT1X | metallothionein 1X | -0.0344404 |
| RPS8 | ribosomal protein S8 | -0.03435 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0331095 |
| S100A10 | S100 calcium binding protein A10 | -0.0328555 |
| TENM3 | teneurin transmembrane protein 3 | -0.0326196 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0322056 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0320633 |
| FOXP1 | forkhead box P1 | -0.031703 |
| RPL35 | ribosomal protein L35 | -0.0303325 |
| SULF1 | sulfatase 1 | -0.0302995 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0300786 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0300784 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0294647 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0293861 |
| SLC38A2 | solute carrier family 38, member 2 | -0.029202 |
| POSTN | periostin, osteoblast specific factor | -0.02863 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0284735 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.02836 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0281688 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0281331 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.028001 |
| SLC12A8 | solute carrier family 12, member 8 | -0.027778 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0275166 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0274859 |
| GNAS | GNAS complex locus | -0.0262775 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262244 |
| TPM1 | tropomyosin 1 (alpha) | -0.0260235 |
| RPS19 | ribosomal protein S19 | -0.0258676 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0257594 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0257304 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0257137 |
| SQSTM1 | sequestosome 1 | -0.0250191 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0247205 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0244744 |
| RPL19 | ribosomal protein L19 | -0.0244031 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0241177 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0240693 |
| RPL26 | ribosomal protein L26 | -0.0239295 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0239154 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.023892 |
| RPL28 | ribosomal protein L28 | -0.023711 |
| RPLP0 | ribosomal protein, large, P0 | -0.0236862 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.023626 |
| RPS13 | ribosomal protein S13 | -0.0236073 |
| KRT7 | keratin 7, type II | -0.0235118 |
