| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.17453 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.126216 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.110149 |
| EXT1 | exostosin glycosyltransferase 1 | 0.100169 |
| PGK1 | phosphoglycerate kinase 1 | 0.0930699 |
| EFNA5 | ephrin-A5 | 0.0812829 |
| RUNX1 | runt-related transcription factor 1 | 0.0787424 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0768213 |
| SPAG9 | sperm associated antigen 9 | 0.0746775 |
| APP | amyloid beta (A4) precursor protein | 0.073357 |
| YBX3 | Y box binding protein 3 | 0.070323 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0665602 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0634374 |
| WDR43 | WD repeat domain 43 | 0.0612061 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.061147 |
| RPL14 | ribosomal protein L14 | 0.0610362 |
| PTK2 | protein tyrosine kinase 2 | 0.0606254 |
| WDR45B | WD repeat domain 45B | 0.0567942 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0563648 |
| CD109 | CD109 molecule | 0.0561281 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.05499 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0532397 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0506664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0503015 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.050135 |
| FMNL2 | formin-like 2 | 0.048855 |
| ATP13A3 | ATPase type 13A3 | 0.0486686 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0484372 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0483884 |
| NUP58 | nucleoporin 58 | 0.0481125 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0480029 |
| RBM39 | RNA binding motif protein 39 | 0.0471836 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0466229 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0463969 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0456089 |
| BRD2 | bromodomain containing 2 | 0.0452954 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.045286 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0449096 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0448811 |
| USP3 | ubiquitin specific peptidase 3 | 0.0448239 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0447845 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0445893 |
| MT2A | metallothionein 2A | 0.0440943 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0440908 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0437182 |
| B2M | beta-2-microglobulin | 0.0435173 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0425016 |
| DST | dystonin | 0.0419717 |
| QKI | QKI, KH domain containing, RNA binding | 0.0405868 |
| RLF | rearranged L-myc fusion | 0.0403169 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0398123 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.039615 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0393112 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0391778 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0391728 |
| ZNF292 | zinc finger protein 292 | 0.0387618 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0387055 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.03815 |
| NCKAP1 | NCK-associated protein 1 | 0.0373505 |
| MMP12 | matrix metallopeptidase 12 | 0.0363001 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0361665 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0361386 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0358364 |
| HELZ | helicase with zinc finger | 0.0354935 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0353284 |
| CDC73 | cell division cycle 73 | 0.0353079 |
| PRRC2A | proline-rich coiled-coil 2A | 0.035278 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0351807 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0340314 |
| TFRC | transferrin receptor | 0.0335202 |
| TOP1 | topoisomerase (DNA) I | 0.0334021 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0333294 |
| OGA | O-GlcNAcase | 0.0331638 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0331104 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0328266 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.032646 |
| FAM162A | family with sequence similarity 162, member A | 0.0325788 |
| RPS3 | ribosomal protein S3 | 0.0323245 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0319454 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318329 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0317974 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0317657 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0317151 |
| RYBP | RING1 and YY1 binding protein | 0.031577 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314713 |
| MYO6 | myosin VI | 0.031405 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.031092 |
| SEPTIN10 | septin 10 | 0.0306949 |
| RTTN | rotatin | 0.030579 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0304154 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0302342 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0301488 |
| TEX10 | testis expressed 10 | 0.0299269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0298586 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0296904 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0296571 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0295878 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0295398 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0294815 |
| CASC3 | cancer susceptibility candidate 3 | 0.0294598 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.405025 |
| POTEF | POTE ankyrin domain family, member F | -0.113497 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.112812 |
| VIM | vimentin | -0.100521 |
| CD44 | CD44 molecule (Indian blood group) | -0.0927124 |
| RPS6 | ribosomal protein S6 | -0.0887025 |
| FTL | ferritin, light polypeptide | -0.0879304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0821406 |
| HMGA1 | high mobility group AT-hook 1 | -0.0796442 |
| ACTG1 | actin gamma 1 | -0.0702078 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0690928 |
| MAP1B | microtubule-associated protein 1B | -0.0609899 |
| NDRG1 | N-myc downstream regulated 1 | -0.0536729 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0481456 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0480509 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0434712 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0433163 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0432501 |
| TXNIP | thioredoxin interacting protein | -0.0432143 |
| CENPF | centromere protein F, 350/400kDa | -0.0400643 |
| PTCHD4 | patched domain containing 4 | -0.0393495 |
| AHNAK | AHNAK nucleoprotein | -0.0389033 |
| LOC112694756 | uncharaterized LOC112694756 | -0.038201 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.037979 |
| STC1 | stanniocalcin 1 | -0.0368224 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332855 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0320252 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0318746 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0316585 |
| HMGA2 | high mobility group AT-hook 2 | -0.0314939 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0314922 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0313901 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0307212 |
| RPS23 | ribosomal protein S23 | -0.0300702 |
| ERBIN | erbb2 interacting protein | -0.0299175 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0297289 |
| NAV1 | neuron navigator 1 | -0.0295794 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0292284 |
| TPI1 | triosephosphate isomerase 1 | -0.0290008 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0288446 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0284031 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0282536 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.028161 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0280899 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0279957 |
| PFN1 | profilin 1 | -0.0274858 |
| RACK1 | receptor for activated C kinase 1 | -0.0274523 |
| KLF6 | Kruppel-like factor 6 | -0.0272417 |
| UBC | ubiquitin C | -0.0270541 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0270022 |
| NLGN1 | neuroligin 1 | -0.0269383 |
| RPS25 | ribosomal protein S25 | -0.0268096 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0266459 |
| RPL35A | ribosomal protein L35a | -0.0264505 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0263963 |
| DIAPH3 | diaphanous-related formin 3 | -0.0254447 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0253459 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0252954 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0250101 |
| LDHA | lactate dehydrogenase A | -0.024999 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.024865 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0245864 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0245367 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0244903 |
| SMAD3 | SMAD family member 3 | -0.0243495 |
| PKM | pyruvate kinase, muscle | -0.0241964 |
| TRAM1 | translocation associated membrane protein 1 | -0.023994 |
| BDNF | brain-derived neurotrophic factor | -0.0238935 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0238762 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0236462 |
| OSMR | oncostatin M receptor | -0.023251 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0231598 |
| LDHB | lactate dehydrogenase B | -0.0225772 |
| TUBB | tubulin, beta class I | -0.0224521 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0219253 |
| PTMA | prothymosin, alpha | -0.0218464 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0218063 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0217478 |
| EXOC4 | exocyst complex component 4 | -0.0217073 |
| RBMX | RNA binding motif protein, X-linked | -0.0216453 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0214791 |
| INTS6 | integrator complex subunit 6 | -0.0212532 |
| MSR1 | macrophage scavenger receptor 1 | -0.0206368 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0206339 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0204738 |
| CCN2 | cellular communication network factor 2 | -0.0204571 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0201774 |
| TENM1 | teneurin transmembrane protein 1 | -0.0200294 |
| PAX3 | paired box 3 | -0.0199616 |
| SNX3 | sorting nexin 3 | -0.0199196 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0198865 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0196985 |
| R3HDM1 | R3H domain containing 1 | -0.019679 |
| PTEN | phosphatase and tensin homolog | -0.0196751 |
| FOSL1 | FOS-like antigen 1 | -0.0196442 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0196087 |
| RPS13 | ribosomal protein S13 | -0.019526 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0194649 |
| CNTLN | centlein, centrosomal protein | -0.0194525 |
| CREBBP | CREB binding protein | -0.0194524 |
