| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0744531 |
| EREG | epiregulin | 0.0703653 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.069083 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0689491 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0675057 |
| FAM13A | family with sequence similarity 13, member A | 0.0647742 |
| PRELID2 | PRELI domain containing 2 | 0.0635654 |
| ASPH | aspartate beta-hydroxylase | 0.0627872 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0626072 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.062416 |
| PTMA | prothymosin, alpha | 0.0605737 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.053191 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0530954 |
| TMSB4X | thymosin beta 4, X-linked | 0.0517952 |
| RNF145 | ring finger protein 145 | 0.0501175 |
| NPSR1 | neuropeptide S receptor 1 | 0.0488971 |
| ZNF292 | zinc finger protein 292 | 0.0488715 |
| CCNY | cyclin Y | 0.0477329 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0462437 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0439733 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0437391 |
| TXNIP | thioredoxin interacting protein | 0.0434561 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0427731 |
| RPL14 | ribosomal protein L14 | 0.0403298 |
| DSPP | dentin sialophosphoprotein | 0.0400826 |
| COPA | coatomer protein complex, subunit alpha | 0.0388054 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0379602 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0377348 |
| NDRG1 | N-myc downstream regulated 1 | 0.0371529 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0363603 |
| EZR | ezrin | 0.036071 |
| MED13L | mediator complex subunit 13-like | 0.035916 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0359083 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.035869 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.035561 |
| B2M | beta-2-microglobulin | 0.0352305 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0351097 |
| CDK19 | cyclin-dependent kinase 19 | 0.0346841 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0346582 |
| RPS12 | ribosomal protein S12 | 0.0342948 |
| FERMT1 | fermitin family member 1 | 0.0341841 |
| PRSS3 | protease, serine, 3 | 0.0340149 |
| VMP1 | vacuole membrane protein 1 | 0.0335329 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0334065 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0328179 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.032221 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316651 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0312315 |
| RPS6 | ribosomal protein S6 | 0.0306162 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0305806 |
| FNBP1L | formin binding protein 1-like | 0.0305351 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0305067 |
| USP53 | ubiquitin specific peptidase 53 | 0.029764 |
| ANXA11 | annexin A11 | 0.0296286 |
| ADD3 | adducin 3 (gamma) | 0.0295895 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0295387 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0289286 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280906 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0280392 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279948 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0279454 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0276384 |
| YTHDC1 | YTH domain containing 1 | 0.0276118 |
| HDGF | hepatoma-derived growth factor | 0.0274925 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0274048 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0273472 |
| SPPL3 | signal peptide peptidase like 3 | 0.0271614 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0271102 |
| SUCO | SUN domain containing ossification factor | 0.0270514 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0270454 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0269653 |
| ITGA6 | integrin, alpha 6 | 0.0265806 |
| NCKAP1 | NCK-associated protein 1 | 0.026454 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0260974 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0260243 |
| PTEN | phosphatase and tensin homolog | 0.0259146 |
| TPM4 | tropomyosin 4 | 0.025754 |
| USP24 | ubiquitin specific peptidase 24 | 0.0256026 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0255962 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0253176 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.025121 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0250655 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | 0.0245592 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.024365 |
| MED13 | mediator complex subunit 13 | 0.0242003 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0239212 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0238966 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0237545 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0234693 |
| OGA | O-GlcNAcase | 0.0234112 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0232351 |
| ZNF148 | zinc finger protein 148 | 0.0230601 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0230276 |
| ABHD2 | abhydrolase domain containing 2 | 0.0229027 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.022555 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0225318 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0224306 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.022408 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0219156 |
| PCBP2 | poly(rC) binding protein 2 | 0.0217897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.296828 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.272461 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.146128 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13664 |
| LOC112694756 | uncharaterized LOC112694756 | -0.105231 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0705913 |
| H1-0 | H1.0 linker histone | -0.0643726 |
| MYO1E | myosin IE | -0.0570603 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0561135 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0556834 |
| CD44 | CD44 molecule (Indian blood group) | -0.0548821 |
| LDHA | lactate dehydrogenase A | -0.0525613 |
| CANX | calnexin | -0.0505739 |
| AGR2 | anterior gradient 2 | -0.0492177 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.048827 |
| RPLP0 | ribosomal protein, large, P0 | -0.048731 |
| ARF1 | ADP-ribosylation factor 1 | -0.0464095 |
| GDF15 | growth differentiation factor 15 | -0.0459362 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0458583 |
| EXT1 | exostosin glycosyltransferase 1 | -0.045262 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0432368 |
| PIGR | polymeric immunoglobulin receptor | -0.0420763 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0413799 |
| HDLBP | high density lipoprotein binding protein | -0.0390091 |
| POF1B | premature ovarian failure, 1B | -0.0387132 |
| RPLP1 | ribosomal protein, large, P1 | -0.0374972 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0363157 |
| CADPS | Ca++-dependent secretion activator | -0.0360686 |
| FHL2 | four and a half LIM domains 2 | -0.0351705 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0350541 |
| ABLIM1 | actin binding LIM protein 1 | -0.0347414 |
| RACK1 | receptor for activated C kinase 1 | -0.0328029 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0317708 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0316671 |
| TMSB10 | thymosin beta 10 | -0.031542 |
| RRBP1 | ribosome binding protein 1 | -0.0315205 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0309096 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0300236 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0297229 |
| LMO7 | LIM domain 7 | -0.0294453 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0289476 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0286313 |
| CCND1 | cyclin D1 | -0.0286022 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0285864 |
| RPL11 | ribosomal protein L11 | -0.0284181 |
| TFRC | transferrin receptor | -0.0284024 |
| VCL | vinculin | -0.0282405 |
| COBL | cordon-bleu WH2 repeat protein | -0.0281415 |
| RPL34 | ribosomal protein L34 | -0.028122 |
| ANXA1 | annexin A1 | -0.0280729 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0280132 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0277386 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0275903 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0274536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0270205 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0269762 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0266491 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.026437 |
| EGR1 | early growth response 1 | -0.0264117 |
| RPS24 | ribosomal protein S24 | -0.0261651 |
| HMGA1 | high mobility group AT-hook 1 | -0.0261606 |
| NFIA | nuclear factor I/A | -0.0260982 |
| PKP4 | plakophilin 4 | -0.0260656 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0260299 |
| KRT19 | keratin 19, type I | -0.0259951 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.025101 |
| ACTN4 | actinin, alpha 4 | -0.0250752 |
| PALLD | palladin, cytoskeletal associated protein | -0.0246633 |
| AHNAK | AHNAK nucleoprotein | -0.0246511 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0246394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0242812 |
| RPL28 | ribosomal protein L28 | -0.0242355 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238892 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.023857 |
| KLF6 | Kruppel-like factor 6 | -0.0237829 |
| SRP72 | signal recognition particle 72kDa | -0.0237438 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0235859 |
| SHROOM3 | shroom family member 3 | -0.0230856 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.023036 |
| LRRK1 | leucine-rich repeat kinase 1 | -0.0230357 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0230147 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0228984 |
| MUC13 | mucin 13, cell surface associated | -0.0228247 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0227244 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.02262 |
| CDK13 | cyclin-dependent kinase 13 | -0.0224253 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0223478 |
| EXOC4 | exocyst complex component 4 | -0.0222619 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0222108 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0221812 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0220637 |
| UBC | ubiquitin C | -0.0219866 |
| TKT | transketolase | -0.0218604 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0218557 |
| DSG2 | desmoglein 2 | -0.0217068 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.021701 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.021663 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0215827 |
| ATF6 | activating transcription factor 6 | -0.0214629 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0211158 |
