| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0965682 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0886124 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0628497 |
| VCL | vinculin | 0.0619582 |
| GOLGA4 | golgin A4 | 0.0574692 |
| EZR | ezrin | 0.0500253 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0455571 |
| PRSS3 | protease, serine, 3 | 0.0447159 |
| FLNB | filamin B, beta | 0.0408181 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0394538 |
| DSCAM | Down syndrome cell adhesion molecule | 0.03865 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0370321 |
| MYO6 | myosin VI | 0.0362461 |
| RBM39 | RNA binding motif protein 39 | 0.035807 |
| SHROOM3 | shroom family member 3 | 0.0354414 |
| CEP95 | centrosomal protein 95kDa | 0.0347255 |
| LAMB3 | laminin, beta 3 | 0.0346325 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0342985 |
| ITGA6 | integrin, alpha 6 | 0.0329576 |
| ABHD17C | abhydrolase domain containing 17C | 0.0326789 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.032656 |
| LRRC1 | leucine rich repeat containing 1 | 0.0321909 |
| PLAC8 | placenta-specific 8 | 0.0321468 |
| RPL14 | ribosomal protein L14 | 0.0321373 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0317641 |
| MYOF | myoferlin | 0.0312991 |
| OGA | O-GlcNAcase | 0.030413 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0304011 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0302457 |
| PRELID2 | PRELI domain containing 2 | 0.0301484 |
| ANXA11 | annexin A11 | 0.0289077 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0287921 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0283939 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0280319 |
| ACTN4 | actinin, alpha 4 | 0.0280218 |
| TRIM2 | tripartite motif containing 2 | 0.0279993 |
| USP3 | ubiquitin specific peptidase 3 | 0.0277803 |
| PLAUR | plasminogen activator, urokinase receptor | 0.027282 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.027114 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0266513 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0261694 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0260309 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0258541 |
| CDK19 | cyclin-dependent kinase 19 | 0.0255692 |
| ETNK1 | ethanolamine kinase 1 | 0.0255158 |
| DSG3 | desmoglein 3 | 0.0253335 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0252269 |
| SLMAP | sarcolemma associated protein | 0.0250311 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0248072 |
| TMEM41B | transmembrane protein 41B | 0.0246781 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0245834 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0244373 |
| NKTR | natural killer cell triggering receptor | 0.0242559 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0230077 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0227783 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.022583 |
| USP53 | ubiquitin specific peptidase 53 | 0.0224347 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0223301 |
| ANLN | anillin, actin binding protein | 0.0219587 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0218628 |
| TJP1 | tight junction protein 1 | 0.0218537 |
| SBF2 | SET binding factor 2 | 0.0216921 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0216396 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0215999 |
| NF1 | neurofibromin 1 | 0.0212892 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0211742 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0207461 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0207277 |
| RRBP1 | ribosome binding protein 1 | 0.0204994 |
| LAMA4 | laminin, alpha 4 | 0.0204838 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0204096 |
| MED13L | mediator complex subunit 13-like | 0.0196563 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0193858 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0192115 |
| AFDN | afadin, adherens junction formation factor | 0.0191449 |
| TUT4 | terminal uridylyl transferase 4 | 0.0191208 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.019106 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0190521 |
| CDC42SE2 | CDC42 small effector 2 | 0.0187769 |
| COG5 | component of oligomeric golgi complex 5 | 0.0187388 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0185117 |
| DSPP | dentin sialophosphoprotein | 0.0185036 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.018358 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0183487 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0183051 |
| THOC2 | THO complex 2 | 0.0181081 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0180251 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0179394 |
| RLF | rearranged L-myc fusion | 0.0178542 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0178013 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0177483 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0175729 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0173887 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0172703 |
| PTEN | phosphatase and tensin homolog | 0.0172459 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0171049 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0170371 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0169832 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0169559 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0169503 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21147 |
| RPLP1 | ribosomal protein, large, P1 | -0.139917 |
| RPS6 | ribosomal protein S6 | -0.136857 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127342 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.118897 |
| RPS8 | ribosomal protein S8 | -0.116107 |
| RPS27A | ribosomal protein S27a | -0.114502 |
| RPS12 | ribosomal protein S12 | -0.104385 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.102997 |
| UBC | ubiquitin C | -0.0976991 |
| PKM | pyruvate kinase, muscle | -0.0853941 |
| RPL23 | ribosomal protein L23 | -0.0846779 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0790967 |
| RPS19 | ribosomal protein S19 | -0.0776002 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0771386 |
| RPLP0 | ribosomal protein, large, P0 | -0.0757188 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0739366 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0732983 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0727498 |
| RPS25 | ribosomal protein S25 | -0.0716624 |
| PTMA | prothymosin, alpha | -0.0700215 |
| RPS23 | ribosomal protein S23 | -0.0695543 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0687068 |
| RPL37A | ribosomal protein L37a | -0.0678692 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0665053 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0662943 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0657715 |
| RACK1 | receptor for activated C kinase 1 | -0.0656629 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0650908 |
| RPLP2 | ribosomal protein, large, P2 | -0.0649953 |
| POTEF | POTE ankyrin domain family, member F | -0.0641097 |
| RPL9 | ribosomal protein L9 | -0.0599701 |
| RPL11 | ribosomal protein L11 | -0.0594458 |
| LDHA | lactate dehydrogenase A | -0.0593758 |
| MYO1E | myosin IE | -0.0591678 |
| ACTG1 | actin gamma 1 | -0.0588826 |
| RPS17 | ribosomal protein S17 | -0.0581309 |
| RPS13 | ribosomal protein S13 | -0.0575781 |
| FAT1 | FAT atypical cadherin 1 | -0.0561637 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0556273 |
| RPL31 | ribosomal protein L31 | -0.0540204 |
| RPL26 | ribosomal protein L26 | -0.0537052 |
| RPL34 | ribosomal protein L34 | -0.0533786 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.051451 |
| RPS3 | ribosomal protein S3 | -0.05092 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0503759 |
| PCBP2 | poly(rC) binding protein 2 | -0.0502992 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0492584 |
| ENO1 | enolase 1, (alpha) | -0.0487112 |
| RPL28 | ribosomal protein L28 | -0.0475316 |
| RPL12 | ribosomal protein L12 | -0.0467613 |
| INTS6 | integrator complex subunit 6 | -0.0463754 |
| RPL35A | ribosomal protein L35a | -0.0462065 |
| RPL37 | ribosomal protein L37 | -0.0452939 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0449857 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0448182 |
| KRT18 | keratin 18, type I | -0.0445087 |
| RPS14 | ribosomal protein S14 | -0.0437865 |
| RPS27 | ribosomal protein S27 | -0.0421299 |
| RPS11 | ribosomal protein S11 | -0.0411947 |
| RPS5 | ribosomal protein S5 | -0.0406383 |
| RPS20 | ribosomal protein S20 | -0.0406313 |
| RPS16 | ribosomal protein S16 | -0.0403262 |
| HLA-B | major histocompatibility complex, class I, B | -0.0402296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0399332 |
| RPL8 | ribosomal protein L8 | -0.0397865 |
| RPS29 | ribosomal protein S29 | -0.0394347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0386643 |
| TMSB10 | thymosin beta 10 | -0.038622 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0377295 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0377139 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.036383 |
| ASPH | aspartate beta-hydroxylase | -0.0362357 |
| RPL4 | ribosomal protein L4 | -0.036196 |
| LRRC23 | leucine rich repeat containing 23 | -0.0358681 |
| RPS24 | ribosomal protein S24 | -0.0357876 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0357502 |
| EGFR | epidermal growth factor receptor | -0.0352103 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0350535 |
| RPL36 | ribosomal protein L36 | -0.0347922 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0343688 |
| RNF213 | ring finger protein 213 | -0.0334181 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0331832 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326891 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0326344 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0319932 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0317653 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.030925 |
| RPL19 | ribosomal protein L19 | -0.0308288 |
| RPL30 | ribosomal protein L30 | -0.0307655 |
| AGR2 | anterior gradient 2 | -0.029752 |
| CAV2 | caveolin 2 | -0.0295092 |
| RPL3 | ribosomal protein L3 | -0.0294409 |
| RPL7 | ribosomal protein L7 | -0.0289368 |
| HMGA1 | high mobility group AT-hook 1 | -0.0288962 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0288367 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.028409 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.028385 |
| RPS4X | ribosomal protein S4, X-linked | -0.0282029 |
| RPL21 | ribosomal protein L21 | -0.0279913 |