| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.0569913 |
| B2M | beta-2-microglobulin | 0.0544434 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0537834 |
| DSCAM | Down syndrome cell adhesion molecule | 0.05305 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0519489 |
| MCL1 | myeloid cell leukemia 1 | 0.0513438 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0498021 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0480618 |
| JMJD1C | jumonji domain containing 1C | 0.0453359 |
| VCL | vinculin | 0.0445765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0445661 |
| LMO7 | LIM domain 7 | 0.0430469 |
| NGLY1 | N-glycanase 1 | 0.0423182 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0419515 |
| SPAG9 | sperm associated antigen 9 | 0.0418551 |
| NPTN | neuroplastin | 0.0374105 |
| ARRDC3 | arrestin domain containing 3 | 0.0348087 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0336833 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0327325 |
| SUCO | SUN domain containing ossification factor | 0.0320609 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0313856 |
| RUNX1 | runt-related transcription factor 1 | 0.0307354 |
| ANO6 | anoctamin 6 | 0.0301076 |
| OGA | O-GlcNAcase | 0.029776 |
| PCBP2 | poly(rC) binding protein 2 | 0.0296672 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0294757 |
| FAM193A | family with sequence similarity 193, member A | 0.0289781 |
| TPD52 | tumor protein D52 | 0.0288473 |
| VMP1 | vacuole membrane protein 1 | 0.0286616 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285029 |
| MKI67 | marker of proliferation Ki-67 | 0.0274398 |
| MYO6 | myosin VI | 0.0267998 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0267847 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0263174 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0258912 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258058 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0257194 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0256558 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0253917 |
| ANXA5 | annexin A5 | 0.0248045 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0246296 |
| FNIP1 | folliculin interacting protein 1 | 0.0243892 |
| MYO5B | myosin VB | 0.0243225 |
| YTHDC1 | YTH domain containing 1 | 0.0241327 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0238428 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0235668 |
| ZNF638 | zinc finger protein 638 | 0.023253 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0231307 |
| EZR | ezrin | 0.0230619 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0229272 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0226799 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223904 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0223548 |
| USP34 | ubiquitin specific peptidase 34 | 0.022327 |
| TOP1 | topoisomerase (DNA) I | 0.0222518 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0220726 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0220669 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0219998 |
| SLTM | SAFB-like, transcription modulator | 0.021985 |
| BRD2 | bromodomain containing 2 | 0.0218718 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0217678 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0217406 |
| PTEN | phosphatase and tensin homolog | 0.021518 |
| TMEM165 | transmembrane protein 165 | 0.0215066 |
| LAMA4 | laminin, alpha 4 | 0.0214762 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0210745 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0209887 |
| MEF2A | myocyte enhancer factor 2A | 0.0209541 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0209513 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0208793 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0206732 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0204255 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.020299 |
| CDC73 | cell division cycle 73 | 0.0200429 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0198917 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0197749 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0197705 |
| CCNL1 | cyclin L1 | 0.0197507 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0196886 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.019612 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0196084 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0195184 |
| USP53 | ubiquitin specific peptidase 53 | 0.0195053 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0194718 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0194405 |
| TJP1 | tight junction protein 1 | 0.0193778 |
| COPA | coatomer protein complex, subunit alpha | 0.0191311 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0190661 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0188572 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0186987 |
| ZNF148 | zinc finger protein 148 | 0.0186774 |
| SYAP1 | synapse associated protein 1 | 0.0186251 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0186174 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0185917 |
| TMF1 | TATA element modulatory factor 1 | 0.018526 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0184651 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.018391 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0181654 |
| DOCK5 | dedicator of cytokinesis 5 | 0.018036 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0178496 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.347375 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.163217 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.159215 |
| EGFR | epidermal growth factor receptor | -0.114445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112172 |
| PTMA | prothymosin, alpha | -0.110681 |
| TMSB10 | thymosin beta 10 | -0.107552 |
| H1-0 | H1.0 linker histone | -0.105944 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102168 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0746814 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0741821 |
| ASPH | aspartate beta-hydroxylase | -0.0737247 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0711829 |
| RPL35A | ribosomal protein L35a | -0.0635646 |
| RPLP1 | ribosomal protein, large, P1 | -0.063484 |
| MT2A | metallothionein 2A | -0.0625922 |
| FTL | ferritin, light polypeptide | -0.0616497 |
| S100A10 | S100 calcium binding protein A10 | -0.0550325 |
| RPLP0 | ribosomal protein, large, P0 | -0.0544526 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0516664 |
| RPS24 | ribosomal protein S24 | -0.0513584 |
| ACTG1 | actin gamma 1 | -0.0507327 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0491633 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0491406 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0482267 |
| LDHA | lactate dehydrogenase A | -0.0426343 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0414342 |
| RNF213 | ring finger protein 213 | -0.0411465 |
| IER3 | immediate early response 3 | -0.0394885 |
| RPS25 | ribosomal protein S25 | -0.0376108 |
| RPL34 | ribosomal protein L34 | -0.0348569 |
| GRAMD1B | GRAM domain containing 1B | -0.0342206 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0328891 |
| RPL12 | ribosomal protein L12 | -0.0323262 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0313086 |
| GM2A | GM2 ganglioside activator | -0.0303922 |
| RPS8 | ribosomal protein S8 | -0.029336 |
| RPS27A | ribosomal protein S27a | -0.0293243 |
| AHNAK | AHNAK nucleoprotein | -0.0285953 |
| CSTB | cystatin B (stefin B) | -0.0285735 |
| RPS23 | ribosomal protein S23 | -0.0285093 |
| CANX | calnexin | -0.0284908 |
| HMGA1 | high mobility group AT-hook 1 | -0.0282853 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0279659 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0274755 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.026748 |
| S100P | S100 calcium binding protein P | -0.0262218 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0257524 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0250953 |
| NPAS2 | neuronal PAS domain protein 2 | -0.024942 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0248598 |
| KRT7 | keratin 7, type II | -0.0247709 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0240174 |
| TPI1 | triosephosphate isomerase 1 | -0.0237364 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.023496 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0231968 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0231462 |
| KRT18 | keratin 18, type I | -0.0229082 |
| PDE8A | phosphodiesterase 8A | -0.0228179 |
| CCND1 | cyclin D1 | -0.0228146 |
| TBC1D22A | TBC1 domain family, member 22A | -0.022795 |
| CDCP1 | CUB domain containing protein 1 | -0.0226893 |
| ZFR | zinc finger RNA binding protein | -0.022217 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0222028 |
| RPL23 | ribosomal protein L23 | -0.0221548 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0219963 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0214762 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.021405 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0211573 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0210586 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0210007 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0209209 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0208948 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0208741 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0208433 |
| AGR2 | anterior gradient 2 | -0.0208351 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0207118 |
| MYOF | myoferlin | -0.0206644 |
| TKT | transketolase | -0.0206006 |
| RPL9 | ribosomal protein L9 | -0.0204357 |
| FLNB | filamin B, beta | -0.0204055 |
| GNAS | GNAS complex locus | -0.0203265 |
| RPL8 | ribosomal protein L8 | -0.0202089 |
| RPS6 | ribosomal protein S6 | -0.0201701 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0199411 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0198355 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0195888 |
| POTEF | POTE ankyrin domain family, member F | -0.0194356 |
| MT1X | metallothionein 1X | -0.019372 |
| RPLP2 | ribosomal protein, large, P2 | -0.019229 |
| STC1 | stanniocalcin 1 | -0.0191942 |
| RPS19 | ribosomal protein S19 | -0.0191768 |
| CST3 | cystatin C | -0.0191444 |
| RPL36A | ribosomal protein L36a | -0.0190391 |
| CAV2 | caveolin 2 | -0.0189212 |
| SLC38A2 | solute carrier family 38, member 2 | -0.01872 |
| ZNF217 | zinc finger protein 217 | -0.0184279 |
| SEC61G | Sec61 gamma subunit | -0.0180924 |
| RPL7 | ribosomal protein L7 | -0.0180154 |
| CD163L1 | CD163 molecule-like 1 | -0.0179945 |
