| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.128443 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0678428 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0657704 |
| MEF2A | myocyte enhancer factor 2A | 0.0621761 |
| NGLY1 | N-glycanase 1 | 0.0603377 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0601341 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0550522 |
| GOLGA4 | golgin A4 | 0.054291 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0500713 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0475788 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0456513 |
| OGA | O-GlcNAcase | 0.0421222 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0421168 |
| B2M | beta-2-microglobulin | 0.0391948 |
| CD109 | CD109 molecule | 0.0391718 |
| COPA | coatomer protein complex, subunit alpha | 0.0385983 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0376136 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0373494 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0362276 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0362232 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0350143 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0340878 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0339552 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0334377 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0332554 |
| TMSB4X | thymosin beta 4, X-linked | 0.0323788 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0312255 |
| SUCO | SUN domain containing ossification factor | 0.0311212 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0310141 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308381 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0307477 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0302831 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0301566 |
| RPL14 | ribosomal protein L14 | 0.0293445 |
| RNF145 | ring finger protein 145 | 0.0293227 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0292407 |
| USP3 | ubiquitin specific peptidase 3 | 0.0288202 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0287459 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.027274 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0271354 |
| FAM13A | family with sequence similarity 13, member A | 0.0268606 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0266213 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0265866 |
| YME1L1 | YME1-like 1 ATPase | 0.0256032 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0255023 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.025491 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0251309 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0250517 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0249907 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0249224 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.024875 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0247593 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0244936 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0243964 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0243562 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0241957 |
| SRP54 | signal recognition particle 54kDa | 0.0241671 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0238533 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0234441 |
| EZR | ezrin | 0.0234326 |
| RAB21 | RAB21, member RAS oncogene family | 0.0229853 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0229625 |
| MXI1 | MAX interactor 1, dimerization protein | 0.022612 |
| YBX1 | Y box binding protein 1 | 0.0225952 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0225267 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0224886 |
| ARF4 | ADP-ribosylation factor 4 | 0.0221113 |
| RAI1 | retinoic acid induced 1 | 0.0216729 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0215885 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0214743 |
| FNBP4 | formin binding protein 4 | 0.0214587 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.0213688 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0213013 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0208464 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0207634 |
| YTHDC1 | YTH domain containing 1 | 0.0206722 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0206381 |
| DOCK5 | dedicator of cytokinesis 5 | 0.020627 |
| CERT1 | ceramide transporter 1 | 0.0200681 |
| TMEM41B | transmembrane protein 41B | 0.0199565 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0193266 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0193241 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0191447 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.019018 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0189836 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0188056 |
| OXSR1 | oxidative stress responsive 1 | 0.0187817 |
| RUNX2 | runt-related transcription factor 2 | 0.0185617 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0185257 |
| PDGFC | platelet derived growth factor C | 0.0184342 |
| SPAG9 | sperm associated antigen 9 | 0.0182246 |
| USP15 | ubiquitin specific peptidase 15 | 0.0178688 |
| RAB18 | RAB18, member RAS oncogene family | 0.0175518 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0175211 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0175121 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.017468 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0172571 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0171493 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0168829 |
| WDR45B | WD repeat domain 45B | 0.0167399 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196484 |
| CD44 | CD44 molecule (Indian blood group) | -0.186703 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.170427 |
| SMAD3 | SMAD family member 3 | -0.127188 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.114481 |
| FNDC3B | fibronectin type III domain containing 3B | -0.114055 |
| MT2A | metallothionein 2A | -0.113841 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.110082 |
| NDRG1 | N-myc downstream regulated 1 | -0.109887 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.094421 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0807363 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.077097 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0742107 |
| FN1 | fibronectin 1 | -0.0729662 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0727035 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0703487 |
| CDCP1 | CUB domain containing protein 1 | -0.070247 |
| STC1 | stanniocalcin 1 | -0.0696278 |
| TGM2 | transglutaminase 2 | -0.0679026 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0672735 |
| USP34 | ubiquitin specific peptidase 34 | -0.0660183 |
| POTEF | POTE ankyrin domain family, member F | -0.0623693 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0608659 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0601333 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0599369 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0594116 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0586637 |
| RAD51B | RAD51 paralog B | -0.0579127 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0565257 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.05645 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0549271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0548336 |
| EFNA5 | ephrin-A5 | -0.0541415 |
| NRP1 | neuropilin 1 | -0.0531843 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0518693 |
| CDH13 | cadherin 13 | -0.0507495 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0506029 |
| PKM | pyruvate kinase, muscle | -0.0489455 |
| HMGA1 | high mobility group AT-hook 1 | -0.0483262 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0474312 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0469628 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0465315 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0454579 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0444419 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.044074 |
| ATXN1 | ataxin 1 | -0.0440332 |
| DST | dystonin | -0.044015 |
| MTSS1 | metastasis suppressor 1 | -0.0439405 |
| ECE1 | endothelin converting enzyme 1 | -0.0433949 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0431164 |
| RPS2 | ribosomal protein S2 | -0.0428324 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.042745 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0421853 |
| UBC | ubiquitin C | -0.0411574 |
| LOXL2 | lysyl oxidase-like 2 | -0.0404666 |
| MYO10 | myosin X | -0.040044 |
| NCOA7 | nuclear receptor coactivator 7 | -0.03992 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0394992 |
| MAP1B | microtubule-associated protein 1B | -0.0393634 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0388292 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0379479 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0378317 |
| GPC6 | glypican 6 | -0.0375756 |
| NRG1 | neuregulin 1 | -0.0373629 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0372622 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0363248 |
| DUSP5 | dual specificity phosphatase 5 | -0.0359622 |
| HAS2 | hyaluronan synthase 2 | -0.0359057 |
| KYNU | kynureninase | -0.035816 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0357295 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0357105 |
| LDHA | lactate dehydrogenase A | -0.0356125 |
| ETV6 | ets variant 6 | -0.0354014 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0348251 |
| FNBP1 | formin binding protein 1 | -0.0345729 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0345519 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0344637 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0340923 |
| NAV2 | neuron navigator 2 | -0.0333846 |
| FRMD4A | FERM domain containing 4A | -0.0333072 |
| MSN | moesin | -0.0331807 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0328491 |
| RPL11 | ribosomal protein L11 | -0.0327312 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0327302 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0325896 |
| ASPH | aspartate beta-hydroxylase | -0.0325614 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0323879 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0321128 |
| IFI44L | interferon-induced protein 44-like | -0.0320351 |
| SLFN5 | schlafen family member 5 | -0.0314633 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0313181 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0312851 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0311889 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0310989 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0308831 |
| TXNRD1 | thioredoxin reductase 1 | -0.0306387 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0306117 |
| RIGI | RNA sensor RIG-I | -0.0305765 |
| GRAMD1B | GRAM domain containing 1B | -0.0302062 |
| MX2 | MX dynamin-like GTPase 2 | -0.0296707 |
