| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.200101 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.10064 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0927293 |
| PRKCA | protein kinase C, alpha | 0.0893115 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.076476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0751206 |
| OGA | O-GlcNAcase | 0.0741011 |
| TOP1 | topoisomerase (DNA) I | 0.0727045 |
| WDR45B | WD repeat domain 45B | 0.0695308 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0687775 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0678916 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0664101 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0663084 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0644565 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0634843 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0630862 |
| CUL3 | cullin 3 | 0.0622904 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0618417 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0615616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0595329 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0584424 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0577259 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0576441 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0575031 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0561985 |
| MYOF | myoferlin | 0.0558857 |
| FUS | FUS RNA binding protein | 0.055838 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0554884 |
| PHF21A | PHD finger protein 21A | 0.055484 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0552136 |
| HMBOX1 | homeobox containing 1 | 0.0548757 |
| USP34 | ubiquitin specific peptidase 34 | 0.0547704 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0544937 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.054117 |
| PGK1 | phosphoglycerate kinase 1 | 0.0538513 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0535897 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0532412 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0530137 |
| FMN1 | formin 1 | 0.0519391 |
| TMSB4X | thymosin beta 4, X-linked | 0.0518048 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0513725 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0503667 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0502423 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0496493 |
| HMGA2 | high mobility group AT-hook 2 | 0.0494418 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0485652 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0482673 |
| SUCO | SUN domain containing ossification factor | 0.0482394 |
| ATF4 | activating transcription factor 4 | 0.0482263 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0480218 |
| ZNF654 | zinc finger protein 654 | 0.0478882 |
| SLTM | SAFB-like, transcription modulator | 0.0478448 |
| GPHN | gephyrin | 0.0478352 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0472908 |
| ERBIN | erbb2 interacting protein | 0.0471619 |
| DTNA | dystrobrevin, alpha | 0.0471194 |
| DUSP10 | dual specificity phosphatase 10 | 0.0469634 |
| B2M | beta-2-microglobulin | 0.0466719 |
| RPS8 | ribosomal protein S8 | 0.0465365 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0463498 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0457277 |
| QKI | QKI, KH domain containing, RNA binding | 0.0448441 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0448324 |
| TPD52 | tumor protein D52 | 0.0446131 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0444103 |
| RBM5 | RNA binding motif protein 5 | 0.0444068 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0436059 |
| RPS24 | ribosomal protein S24 | 0.043588 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0434831 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0434138 |
| NUMB | numb homolog (Drosophila) | 0.0433731 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0433337 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0422181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0415712 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0412704 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0410989 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0410725 |
| RPL12 | ribosomal protein L12 | 0.0410278 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0408418 |
| IGF2 | insulin-like growth factor 2 | 0.0405839 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0403355 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0403337 |
| ANXA2 | annexin A2 | 0.0400874 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0396709 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0391677 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.038975 |
| RPS3 | ribosomal protein S3 | 0.0387635 |
| SLK | STE20-like kinase | 0.0387376 |
| MT2A | metallothionein 2A | 0.0387362 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0384636 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0384282 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0380596 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0380399 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0376649 |
| RBM15 | RNA binding motif protein 15 | 0.0375467 |
| ZNF148 | zinc finger protein 148 | 0.0369567 |
| RNF149 | ring finger protein 149 | 0.0366502 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.036311 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0359338 |
| BPTF | bromodomain PHD finger transcription factor | 0.0355651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.17147 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.133031 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0991607 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0987033 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0898558 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0884725 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0850957 |
| RUNX1 | runt-related transcription factor 1 | -0.0830097 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0758431 |
| LDHA | lactate dehydrogenase A | -0.0734531 |
| LMO7 | LIM domain 7 | -0.0731953 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0682813 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.06607 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0658802 |
| USP33 | ubiquitin specific peptidase 33 | -0.0622778 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0613284 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0603025 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.059424 |
| RPL8 | ribosomal protein L8 | -0.0594154 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0591087 |
| GOLGB1 | golgin B1 | -0.0586372 |
| RTN4 | reticulon 4 | -0.0581388 |
| MAP4 | microtubule-associated protein 4 | -0.0570672 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.056747 |
| PLK2 | polo-like kinase 2 | -0.0567125 |
| LAMC2 | laminin, gamma 2 | -0.0566273 |
| AHNAK | AHNAK nucleoprotein | -0.0565057 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0561649 |
| KLF6 | Kruppel-like factor 6 | -0.0556688 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0556249 |
| ZNF292 | zinc finger protein 292 | -0.0550868 |
| SRPK2 | SRSF protein kinase 2 | -0.0544147 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0533096 |
| RBM47 | RNA binding motif protein 47 | -0.0520153 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0516549 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0514986 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0513194 |
| WAPL | WAPL cohesin release factor | -0.05117 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0505624 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0503629 |
| CPE | carboxypeptidase E | -0.0499109 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0480628 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0474287 |
| SEPTIN7 | septin 7 | -0.0474122 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0471324 |
| NUP98 | nucleoporin 98kDa | -0.0468365 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0467257 |
| PTMA | prothymosin, alpha | -0.0467178 |
| RPS5 | ribosomal protein S5 | -0.0465227 |
| SRP72 | signal recognition particle 72kDa | -0.0459011 |
| TUSC3 | tumor suppressor candidate 3 | -0.0455001 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0447202 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0442418 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0441953 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0440519 |
| NHSL1 | NHS-like 1 | -0.0437084 |
| DSPP | dentin sialophosphoprotein | -0.0435756 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0434734 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0433758 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.043299 |
| PLAUR | plasminogen activator, urokinase receptor | -0.043001 |
| TPM4 | tropomyosin 4 | -0.0429137 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0428174 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0427821 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0427216 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0419493 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0419455 |
| URI1 | URI1, prefoldin-like chaperone | -0.041151 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0411347 |
| RPS20 | ribosomal protein S20 | -0.0409266 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0404712 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0403876 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0401717 |
| PLEC | plectin | -0.0401282 |
| EXOC1 | exocyst complex component 1 | -0.0400513 |
| JMJD1C | jumonji domain containing 1C | -0.0398275 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0393796 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.0393081 |
| ZNF638 | zinc finger protein 638 | -0.0389865 |
| RPS19 | ribosomal protein S19 | -0.0389848 |
| UBAP1 | ubiquitin associated protein 1 | -0.0387868 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0386705 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.038565 |
| MUC16 | mucin 16, cell surface associated | -0.0378055 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0369425 |
| SMAD2 | SMAD family member 2 | -0.0368144 |
| SDCBP | syndecan binding protein (syntenin) | -0.0367857 |
| LAMB1 | laminin, beta 1 | -0.0366467 |
| RPLP1 | ribosomal protein, large, P1 | -0.0362053 |
| SFTPA2 | surfactant protein A2 | -0.0361583 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0358455 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0358424 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0358179 |
| MXD1 | MAX dimerization protein 1 | -0.0357973 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0357538 |
| HLA-B | major histocompatibility complex, class I, B | -0.035538 |
| CDK19 | cyclin-dependent kinase 19 | -0.0351325 |
| CD2AP | CD2-associated protein | -0.0350219 |
| GLRX3 | glutaredoxin 3 | -0.0350009 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0347897 |
