| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.177461 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.1135 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.100734 |
| RTN4 | reticulon 4 | 0.0803471 |
| OGA | O-GlcNAcase | 0.067012 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0617999 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0578366 |
| TMEM41B | transmembrane protein 41B | 0.0535922 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0462509 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0457777 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0444581 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0441995 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0424139 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0411395 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0411015 |
| RAB10 | RAB10, member RAS oncogene family | 0.0402485 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.039472 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0381581 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0375921 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0372424 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0363432 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0361089 |
| MMP12 | matrix metallopeptidase 12 | 0.0356512 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0355237 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.035173 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0349637 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0346962 |
| XPO1 | exportin 1 | 0.0346317 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345876 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0344455 |
| ZNF292 | zinc finger protein 292 | 0.0336388 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.032084 |
| FNIP1 | folliculin interacting protein 1 | 0.0318925 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0313595 |
| YBX3 | Y box binding protein 3 | 0.0308663 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0305102 |
| TPM3 | tropomyosin 3 | 0.0303801 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0302811 |
| PGK1 | phosphoglycerate kinase 1 | 0.0302733 |
| GOLGA4 | golgin A4 | 0.0302067 |
| NGLY1 | N-glycanase 1 | 0.0298389 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0291648 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0290315 |
| SPAG9 | sperm associated antigen 9 | 0.0282613 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0282484 |
| JMJD1C | jumonji domain containing 1C | 0.0277777 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0277669 |
| MYO6 | myosin VI | 0.0274523 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0274227 |
| GDI2 | GDP dissociation inhibitor 2 | 0.027332 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0269979 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0269265 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268833 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0268216 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0266964 |
| MSN | moesin | 0.0266471 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0263893 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0262629 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0259899 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0256698 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0256406 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0256 |
| CEP95 | centrosomal protein 95kDa | 0.025427 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0253271 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0244822 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0242996 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0242231 |
| PLIN3 | perilipin 3 | 0.0241549 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0241332 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0239381 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0237063 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0235945 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0234409 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0233606 |
| PNN | pinin, desmosome associated protein | 0.0230655 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0229598 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0228603 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0228601 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.02256 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0224578 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0224435 |
| CD2AP | CD2-associated protein | 0.022026 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0218211 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0216706 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0216611 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0215715 |
| TMEM165 | transmembrane protein 165 | 0.0215551 |
| SERINC1 | serine incorporator 1 | 0.0215383 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0214518 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0214274 |
| RNF169 | ring finger protein 169 | 0.0214251 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.021425 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0212837 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0212595 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0212026 |
| ZNF146 | zinc finger protein 146 | 0.0211301 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0209038 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0208677 |
| RAP1A | RAP1A, member of RAS oncogene family | 0.0207274 |
| STK4 | serine/threonine kinase 4 | 0.0205804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231663 |
| EGR1 | early growth response 1 | -0.113869 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.108922 |
| PDE10A | phosphodiesterase 10A | -0.0769843 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0730537 |
| POTEF | POTE ankyrin domain family, member F | -0.0714873 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0690069 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0674013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.062898 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0609762 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0579102 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0523932 |
| WWOX | WW domain containing oxidoreductase | -0.0502601 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0495917 |
| TMSB10 | thymosin beta 10 | -0.0489955 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.047848 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0431689 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0431603 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0417685 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0417665 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0410346 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0408803 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0400977 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0395853 |
| EXOC4 | exocyst complex component 4 | -0.0387868 |
| ZNF638 | zinc finger protein 638 | -0.0387663 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0382885 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0376561 |
| INTS6 | integrator complex subunit 6 | -0.0373519 |
| PRELID2 | PRELI domain containing 2 | -0.036618 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0362423 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0361504 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0361311 |
| ACTG1 | actin gamma 1 | -0.0357535 |
| RYR3 | ryanodine receptor 3 | -0.0355895 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0351446 |
| HMGA1 | high mobility group AT-hook 1 | -0.0348921 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0345863 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0342369 |
| RNF213 | ring finger protein 213 | -0.0341594 |
| PFN1 | profilin 1 | -0.0341201 |
| ZNF207 | zinc finger protein 207 | -0.0337236 |
| ATG7 | autophagy related 7 | -0.0336984 |
| ATP11A | ATPase, class VI, type 11A | -0.033385 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0327189 |
| TPI1 | triosephosphate isomerase 1 | -0.0323553 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0319655 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0318981 |
| NABP1 | nucleic acid binding protein 1 | -0.0317683 |
| CUX1 | cut-like homeobox 1 | -0.0314605 |
| PRKCE | protein kinase C, epsilon | -0.0313948 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0306333 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302291 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0297151 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0294234 |
| AEBP2 | AE binding protein 2 | -0.0294206 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0290534 |
| HMGA2 | high mobility group AT-hook 2 | -0.0289799 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0286889 |
| GNAS | GNAS complex locus | -0.0284237 |
| ATXN1 | ataxin 1 | -0.0283629 |
| HMGB1 | high mobility group box 1 | -0.0279382 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0272832 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0270578 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0265649 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0258025 |
| RPS20 | ribosomal protein S20 | -0.025612 |
| EFNA5 | ephrin-A5 | -0.0254737 |
| SVIL | supervillin | -0.0254376 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0254065 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0247012 |
| OSMR | oncostatin M receptor | -0.0246225 |
| RPS8 | ribosomal protein S8 | -0.0246166 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0245892 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0244843 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0243108 |
| FLNA | filamin A, alpha | -0.0242259 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0242175 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0241804 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0240603 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235928 |
| E2F3 | E2F transcription factor 3 | -0.0235214 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0233932 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0232942 |
| PCBP2 | poly(rC) binding protein 2 | -0.0232297 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0230174 |
| CCNL1 | cyclin L1 | -0.0228049 |
| RPL11 | ribosomal protein L11 | -0.0227862 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0227398 |
| RBM39 | RNA binding motif protein 39 | -0.0225519 |
| TAPBP | TAP binding protein (tapasin) | -0.0225492 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0224999 |
| GPATCH2L | G patch domain containing 2-like | -0.0224605 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0224286 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0224104 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.022385 |
| RPS15 | ribosomal protein S15 | -0.0223069 |
| LRRC23 | leucine rich repeat containing 23 | -0.0222969 |
| NDRG1 | N-myc downstream regulated 1 | -0.0222744 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0221973 |
