| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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198 genes differentially expressed following the Indacaterol (maleate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.188243 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.134045 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.132005 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.124812 |
| CD109 | CD109 molecule | 0.107239 |
| FLNB | filamin B, beta | 0.105755 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.101968 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0997895 |
| NDRG1 | N-myc downstream regulated 1 | 0.0986696 |
| FAM13A | family with sequence similarity 13, member A | 0.094762 |
| STC1 | stanniocalcin 1 | 0.0941338 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0939841 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0900379 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0855028 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0830975 |
| FMNL2 | formin-like 2 | 0.0821294 |
| LDHA | lactate dehydrogenase A | 0.0810538 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0794153 |
| TOP1 | topoisomerase (DNA) I | 0.0789406 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0782148 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0781339 |
| PGK1 | phosphoglycerate kinase 1 | 0.0771443 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0756304 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0755936 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0717223 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0699203 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0684001 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0671828 |
| GOLGA4 | golgin A4 | 0.0637662 |
| FTL | ferritin, light polypeptide | 0.0634427 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0628807 |
| SPAG9 | sperm associated antigen 9 | 0.0628781 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0600346 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0590244 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0583105 |
| DSCAM | Down syndrome cell adhesion molecule | 0.058242 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0577041 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0550394 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0550213 |
| LMO7 | LIM domain 7 | 0.0539632 |
| SETD5 | SET domain containing 5 | 0.0523296 |
| HMGA2 | high mobility group AT-hook 2 | 0.0511579 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0505055 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0494748 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0477702 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0469159 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0451849 |
| PKM | pyruvate kinase, muscle | 0.0421372 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0414877 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405402 |
| NUP58 | nucleoporin 58 | 0.040087 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0380731 |
| USP34 | ubiquitin specific peptidase 34 | 0.0379417 |
| PRKCA | protein kinase C, alpha | 0.0365346 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0357073 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0356227 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0353228 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0339731 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0329973 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0328086 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0327646 |
| GLG1 | golgi glycoprotein 1 | 0.0322353 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0320625 |
| GOLGB1 | golgin B1 | 0.0320498 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0314392 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0286586 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0286432 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.027435 |
| CUX1 | cut-like homeobox 1 | 0.0272812 |
| PTK2 | protein tyrosine kinase 2 | 0.0257077 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0252009 |
| OXR1 | oxidation resistance 1 | 0.0242927 |
| PARD3 | par-3 family cell polarity regulator | 0.0238228 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.02327 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227668 |
| USP3 | ubiquitin specific peptidase 3 | 0.0223836 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223027 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.022301 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0218837 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0190707 |
| GPHN | gephyrin | 0.0187232 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0186198 |
| JMJD1C | jumonji domain containing 1C | 0.0183217 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0147365 |
| RPS6 | ribosomal protein S6 | 0.0136239 |
| CAVIN1 | caveolae associated protein 1 | 0.0125978 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0121891 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0117093 |
| RPL23 | ribosomal protein L23 | 0.00814447 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0062964 |
| FMN1 | formin 1 | 0.00463366 |
| COG5 | component of oligomeric golgi complex 5 | 0.0043997 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0023734 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00169084 |
| ANXA2 | annexin A2 | 0.0016673 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 8.50826E-4 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 5.17069E-4 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 4.69429E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.19078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.161197 |
| VIM | vimentin | -0.140603 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.136547 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0991467 |
| EFNA5 | ephrin-A5 | -0.0919501 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0903662 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0869884 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0758741 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0755518 |
| TXNIP | thioredoxin interacting protein | -0.0743068 |
| HDLBP | high density lipoprotein binding protein | -0.069664 |
| KIF5B | kinesin family member 5B | -0.0664944 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0659066 |
| RPS24 | ribosomal protein S24 | -0.0657482 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0633758 |
| RPL26 | ribosomal protein L26 | -0.0626803 |
| SLC38A1 | solute carrier family 38, member 1 | -0.06192 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0618656 |
| CALR | calreticulin | -0.0614224 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0587733 |
| RBM25 | RNA binding motif protein 25 | -0.0566543 |
| PTMA | prothymosin, alpha | -0.056273 |
| RTN4 | reticulon 4 | -0.0562192 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0561642 |
| CEP170 | centrosomal protein 170kDa | -0.0559191 |
| TMSB10 | thymosin beta 10 | -0.0530684 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0496116 |
| CCNI | cyclin I | -0.0486838 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0482396 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0473668 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0465011 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0463686 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0460557 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0450971 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.043423 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0432369 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0427275 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0415688 |
| VCL | vinculin | -0.0405877 |
| CANX | calnexin | -0.040452 |
| GLIS3 | GLIS family zinc finger 3 | -0.0397807 |
| CDH13 | cadherin 13 | -0.0383722 |
| AHNAK | AHNAK nucleoprotein | -0.0383236 |
| UBC | ubiquitin C | -0.0381869 |
| MYOF | myoferlin | -0.0370814 |
| TMEM165 | transmembrane protein 165 | -0.0367177 |
| RNF213 | ring finger protein 213 | -0.0363506 |
| B2M | beta-2-microglobulin | -0.0357017 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0345398 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0341388 |
| SP100 | SP100 nuclear antigen | -0.0341278 |
| CD44 | CD44 molecule (Indian blood group) | -0.0336706 |
| LMNA | lamin A/C | -0.033669 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.032948 |
| ACTN4 | actinin, alpha 4 | -0.0327361 |
| RPL37A | ribosomal protein L37a | -0.0318627 |
| SMYD3 | SET and MYND domain containing 3 | -0.0311114 |
| MED13 | mediator complex subunit 13 | -0.030918 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0301961 |
| MORF4L2 | mortality factor 4 like 2 | -0.0299651 |
| OGA | O-GlcNAcase | -0.0299015 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0291785 |
| MED13L | mediator complex subunit 13-like | -0.0287655 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0275959 |
| MYO10 | myosin X | -0.0273781 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.02707 |
| EGFR | epidermal growth factor receptor | -0.0266457 |
| RPS27A | ribosomal protein S27a | -0.0263243 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0256068 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0252495 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.025163 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0247298 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0245782 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0243654 |
| MAP4 | microtubule-associated protein 4 | -0.0235044 |
| ZNF292 | zinc finger protein 292 | -0.0235011 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0228728 |
| MT2A | metallothionein 2A | -0.0226089 |
| INHBA | inhibin, beta A | -0.022538 |
| ZNF609 | zinc finger protein 609 | -0.0219447 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0212919 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0209545 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0205264 |
| RPLP1 | ribosomal protein, large, P1 | -0.0203736 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.019494 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.019221 |
| MYO6 | myosin VI | -0.0187188 |
| RPL31 | ribosomal protein L31 | -0.0181859 |
| TXNRD1 | thioredoxin reductase 1 | -0.0166693 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0160347 |
| RLF | rearranged L-myc fusion | -0.0152172 |
| ACTG1 | actin gamma 1 | -0.0150622 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0148258 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0146324 |
| GPC6 | glypican 6 | -0.0137191 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0124319 |
| SMAD3 | SMAD family member 3 | -0.0119556 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0115041 |
