| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.0958021 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0930279 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0590434 |
| B2M | beta-2-microglobulin | 0.0547698 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0545608 |
| HDAC9 | histone deacetylase 9 | 0.0517345 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0463282 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0462924 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0450061 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0406994 |
| TPM3 | tropomyosin 3 | 0.0396924 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0393451 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0391505 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0389502 |
| ITGAV | integrin, alpha V | 0.0388414 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0386103 |
| CDC73 | cell division cycle 73 | 0.0375938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370486 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0360131 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346553 |
| SET | SET nuclear proto-oncogene | 0.0336115 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0335167 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0328086 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.032486 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0324105 |
| SPAG9 | sperm associated antigen 9 | 0.0323451 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.031574 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0315683 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0308657 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0305167 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0302213 |
| MED13L | mediator complex subunit 13-like | 0.0300897 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0300053 |
| NCKAP1 | NCK-associated protein 1 | 0.0299964 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0297551 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0295833 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0293215 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0292898 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0286186 |
| MEMO1 | mediator of cell motility 1 | 0.0284329 |
| MEF2A | myocyte enhancer factor 2A | 0.0277268 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0274791 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0274102 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0270021 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0269172 |
| CCNL1 | cyclin L1 | 0.0267935 |
| USP53 | ubiquitin specific peptidase 53 | 0.0263539 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0263149 |
| RPS2 | ribosomal protein S2 | 0.0262989 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0262954 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0262672 |
| CANX | calnexin | 0.0260375 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.026015 |
| EZR | ezrin | 0.0258847 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0254897 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0254496 |
| QKI | QKI, KH domain containing, RNA binding | 0.0252126 |
| MITF | microphthalmia-associated transcription factor | 0.025192 |
| PCDH18 | protocadherin 18 | 0.0251388 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0251329 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0250204 |
| RPL3 | ribosomal protein L3 | 0.0248395 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0248329 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0247989 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245906 |
| FNBP1L | formin binding protein 1-like | 0.0240386 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0239829 |
| NRDC | nardilysin convertase | 0.0238443 |
| PNN | pinin, desmosome associated protein | 0.0237305 |
| RPS12 | ribosomal protein S12 | 0.0236148 |
| SETD5 | SET domain containing 5 | 0.0236094 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0234776 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0234192 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0232325 |
| CALR | calreticulin | 0.0230834 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0229837 |
| FMR1 | fragile X mental retardation 1 | 0.0229168 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0228607 |
| MCL1 | myeloid cell leukemia 1 | 0.0227608 |
| PRKCI | protein kinase C, iota | 0.022745 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226809 |
| ANXA1 | annexin A1 | 0.0226177 |
| EEIG2 | EEIG family member 2 | 0.0225167 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0223917 |
| CBX3 | chromobox homolog 3 | 0.0221657 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0221546 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0220806 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0220767 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0219733 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0217865 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0216885 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0215462 |
| RYBP | RING1 and YY1 binding protein | 0.0213317 |
| SUCO | SUN domain containing ossification factor | 0.0212979 |
| WDR12 | WD repeat domain 12 | 0.0211379 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0210968 |
| JUN | jun proto-oncogene | 0.0210815 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0210531 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0210082 |
| RANBP9 | RAN binding protein 9 | 0.0209774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.167002 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.132335 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.103202 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.101383 |
| COL5A2 | collagen, type V, alpha 2 | -0.0990824 |
| CADM2 | cell adhesion molecule 2 | -0.0986207 |
| FOXP2 | forkhead box P2 | -0.0974624 |
| DST | dystonin | -0.0961 |
| TENM3 | teneurin transmembrane protein 3 | -0.093987 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0874277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0841665 |
| ACTG1 | actin gamma 1 | -0.0810957 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0808844 |
| VIM | vimentin | -0.0770186 |
| MEIS2 | Meis homeobox 2 | -0.0667068 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0644837 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0581781 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.057828 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0577917 |
| RPLP1 | ribosomal protein, large, P1 | -0.0551197 |
| TMSB10 | thymosin beta 10 | -0.054139 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0536081 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0527578 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.051564 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0513658 |
| HMGA2 | high mobility group AT-hook 2 | -0.050299 |
| H1-0 | H1.0 linker histone | -0.0500127 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0487914 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0464598 |
| SYT1 | synaptotagmin I | -0.045053 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0446133 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0437725 |
| AHNAK | AHNAK nucleoprotein | -0.0426065 |
| PRKD1 | protein kinase D1 | -0.0420754 |
| GPC3 | glypican 3 | -0.0419091 |
| RPS16 | ribosomal protein S16 | -0.0416121 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0413223 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0409267 |
| SMYD3 | SET and MYND domain containing 3 | -0.0405426 |
| LAMA4 | laminin, alpha 4 | -0.0396893 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.037772 |
| METAP2 | methionyl aminopeptidase 2 | -0.0368711 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0366294 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0363478 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0363192 |
| DMD | dystrophin | -0.0360321 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355246 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0350648 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0347871 |
| RPL35A | ribosomal protein L35a | -0.0342384 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0339673 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0339558 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0337508 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0337099 |
| TPX2 | TPX2, microtubule-associated | -0.0333038 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0332686 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0332159 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0322264 |
| ACTN4 | actinin, alpha 4 | -0.0312336 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0312035 |
| NFIA | nuclear factor I/A | -0.0307525 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.030364 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0303544 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0302331 |
| RPL30 | ribosomal protein L30 | -0.0300761 |
| ZNF385D | zinc finger protein 385D | -0.0299954 |
| NEBL | nebulette | -0.0295278 |
| CUX1 | cut-like homeobox 1 | -0.0291397 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.028904 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0288286 |
| CLTC | clathrin, heavy chain (Hc) | -0.0288231 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.028816 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0282022 |
| RAD51B | RAD51 paralog B | -0.0281015 |
| MKI67 | marker of proliferation Ki-67 | -0.0274149 |
| HMGB1 | high mobility group box 1 | -0.0273957 |
| COL3A1 | collagen, type III, alpha 1 | -0.0273326 |
| AK1 | adenylate kinase 1 | -0.0272415 |
| VCL | vinculin | -0.0271878 |
| COL1A2 | collagen, type I, alpha 2 | -0.027112 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0264769 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.026147 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0259774 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0257055 |
| HMGB2 | high mobility group box 2 | -0.0256603 |
| BPTF | bromodomain PHD finger transcription factor | -0.0254633 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0253978 |
| SIK2 | salt-inducible kinase 2 | -0.0250076 |
| SGO2 | shugoshin 2 | -0.0248039 |
| ANXA2 | annexin A2 | -0.0243627 |
| CENPE | centromere protein E, 312kDa | -0.0242884 |
| SHROOM3 | shroom family member 3 | -0.02427 |
| FBXO17 | F-box protein 17 | -0.0241962 |
| PRELID2 | PRELI domain containing 2 | -0.0237327 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0237159 |
| SRP72 | signal recognition particle 72kDa | -0.0236908 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0235462 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0234472 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0234333 |
| TXNRD1 | thioredoxin reductase 1 | -0.0232972 |
