| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0787844 |
| OGA | O-GlcNAcase | 0.0643141 |
| FMNL2 | formin-like 2 | 0.0616678 |
| SNX14 | sorting nexin 14 | 0.060123 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0581603 |
| SPAG9 | sperm associated antigen 9 | 0.0574133 |
| B2M | beta-2-microglobulin | 0.0477905 |
| SUCO | SUN domain containing ossification factor | 0.047449 |
| VCL | vinculin | 0.0463051 |
| FBL | fibrillarin | 0.0421297 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0408952 |
| TMEM41B | transmembrane protein 41B | 0.0395652 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0365411 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.034515 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0341702 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0340843 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0319109 |
| WDR45B | WD repeat domain 45B | 0.0307019 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.030235 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0299085 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029692 |
| COPA | coatomer protein complex, subunit alpha | 0.0296272 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0295489 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0291188 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.028762 |
| PGK1 | phosphoglycerate kinase 1 | 0.0282398 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0268003 |
| USP3 | ubiquitin specific peptidase 3 | 0.0262911 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0259119 |
| GOLGA4 | golgin A4 | 0.0255819 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0254355 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0252207 |
| SRP54 | signal recognition particle 54kDa | 0.024785 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0240278 |
| CTBP2 | C-terminal binding protein 2 | 0.023951 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0236771 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0234026 |
| WDR43 | WD repeat domain 43 | 0.022982 |
| NUP58 | nucleoporin 58 | 0.02286 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0228428 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022063 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 0.0219582 |
| TMSB4X | thymosin beta 4, X-linked | 0.0217135 |
| DENND5A | DENN/MADD domain containing 5A | 0.0216463 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0216449 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0215847 |
| RAB1A | RAB1A, member RAS oncogene family | 0.021282 |
| ATP13A3 | ATPase type 13A3 | 0.0212394 |
| ARF4 | ADP-ribosylation factor 4 | 0.0211201 |
| SEC24A | SEC24 family member A | 0.0210017 |
| TPD52 | tumor protein D52 | 0.0207883 |
| ADM | adrenomedullin | 0.0206033 |
| NOP58 | NOP58 ribonucleoprotein | 0.0205386 |
| FOXJ3 | forkhead box J3 | 0.0203039 |
| CA8 | carbonic anhydrase VIII | 0.0202909 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0199417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.019821 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0197684 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0196657 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0196202 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0195802 |
| TFG | TRK-fused gene | 0.0195328 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0194805 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0194069 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0193727 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.019167 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0187046 |
| JMJD1C | jumonji domain containing 1C | 0.0186441 |
| RPL14 | ribosomal protein L14 | 0.0186165 |
| RLF | rearranged L-myc fusion | 0.0184994 |
| SAFB2 | scaffold attachment factor B2 | 0.0183288 |
| MATR3 | matrin 3 | 0.0182791 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0181971 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0180124 |
| PDE7A | phosphodiesterase 7A | 0.0179069 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0176378 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0175077 |
| MLF1 | myeloid leukemia factor 1 | 0.01742 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.017313 |
| CRY1 | cryptochrome circadian clock 1 | 0.0170711 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0169941 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0169098 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0169015 |
| RASA3 | RAS p21 protein activator 3 | 0.0168225 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0166069 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0165825 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0165427 |
| CCNL1 | cyclin L1 | 0.016385 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0162461 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.016207 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0162051 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0161802 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0161676 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0161016 |
| BRD2 | bromodomain containing 2 | 0.0160071 |
| MCL1 | myeloid cell leukemia 1 | 0.0159698 |
| ANLN | anillin, actin binding protein | 0.0159315 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0158499 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.015811 |
| RAB18 | RAB18, member RAS oncogene family | 0.0158037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.158733 |
| CD44 | CD44 molecule (Indian blood group) | -0.136497 |
| DST | dystonin | -0.127432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.104294 |
| SLC35F3 | solute carrier family 35, member F3 | -0.101018 |
| EGFR | epidermal growth factor receptor | -0.0956152 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0891198 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0848311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0837118 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0822672 |
| ZNF780B | zinc finger protein 780B | -0.0806384 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0797407 |
| ACTN4 | actinin, alpha 4 | -0.0774145 |
| ASPH | aspartate beta-hydroxylase | -0.0767994 |
| AHNAK | AHNAK nucleoprotein | -0.0748156 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.072661 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0669864 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0668646 |
| VIM | vimentin | -0.0650729 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0647419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0646994 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0614907 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0614735 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.061015 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0577577 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0561168 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0537321 |
| EXOC4 | exocyst complex component 4 | -0.0499085 |
| EHBP1 | EH domain binding protein 1 | -0.0497836 |
| MAP1B | microtubule-associated protein 1B | -0.0496741 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0496529 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.048906 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0482081 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0481546 |
| SMYD3 | SET and MYND domain containing 3 | -0.0477855 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0469954 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0465843 |
| PHF14 | PHD finger protein 14 | -0.0464467 |
| EFNA5 | ephrin-A5 | -0.0461255 |
| RASAL2 | RAS protein activator like 2 | -0.0450107 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0447799 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0433694 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0433087 |
| MYO9A | myosin IXA | -0.0425758 |
| PTK2 | protein tyrosine kinase 2 | -0.042476 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0420051 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.041865 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0417633 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0409009 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0404576 |
| UTRN | utrophin | -0.0404097 |
| CENPF | centromere protein F, 350/400kDa | -0.0403045 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0394533 |
| SFTPA2 | surfactant protein A2 | -0.0384502 |
| ATXN1 | ataxin 1 | -0.0382621 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0381537 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0377691 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0374772 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.037262 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0370771 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0368702 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0368321 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.036586 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0363776 |
| NF1 | neurofibromin 1 | -0.0359511 |
| ATM | ATM serine/threonine kinase | -0.0353654 |
| TNS3 | tensin 3 | -0.0352926 |
| RAD51B | RAD51 paralog B | -0.0351034 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0346681 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.034545 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | -0.0340949 |
| ATP9B | ATPase, class II, type 9B | -0.0339028 |
| OSMR | oncostatin M receptor | -0.0337495 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0331302 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0325895 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0324631 |
| ATG7 | autophagy related 7 | -0.0324376 |
| CTSD | cathepsin D | -0.0322999 |
| FRMD5 | FERM domain containing 5 | -0.0321348 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321095 |
| MKI67 | marker of proliferation Ki-67 | -0.0320421 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0319952 |
| DSTN | destrin (actin depolymerizing factor) | -0.0318464 |
| RPL11 | ribosomal protein L11 | -0.0317927 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0316332 |
| HMGA1 | high mobility group AT-hook 1 | -0.031538 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0314016 |
| RNF213 | ring finger protein 213 | -0.0313818 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0312759 |
| LDHA | lactate dehydrogenase A | -0.0309423 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0307432 |
| PRSS23 | protease, serine, 23 | -0.0307044 |
| HMGA2 | high mobility group AT-hook 2 | -0.0297927 |
| SMAD3 | SMAD family member 3 | -0.0296861 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.029547 |
| DIAPH2 | diaphanous-related formin 2 | -0.0294993 |
| ATG10 | autophagy related 10 | -0.0293777 |
| POTEF | POTE ankyrin domain family, member F | -0.0293312 |
| DOCK5 | dedicator of cytokinesis 5 | -0.029191 |
| MYADM | myeloid-associated differentiation marker | -0.0289881 |