| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.233475 |
| COL1A1 | collagen, type I, alpha 1 | 0.095223 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0946312 |
| HLA-B | major histocompatibility complex, class I, B | 0.0734663 |
| PCBP3 | poly(rC) binding protein 3 | 0.0629115 |
| CD109 | CD109 molecule | 0.0612125 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0587474 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0577788 |
| COL1A2 | collagen, type I, alpha 2 | 0.0545201 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0524781 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0507516 |
| MEF2A | myocyte enhancer factor 2A | 0.046597 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0446024 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.042072 |
| COPA | coatomer protein complex, subunit alpha | 0.0417483 |
| MMP12 | matrix metallopeptidase 12 | 0.0414525 |
| COL5A1 | collagen, type V, alpha 1 | 0.0403372 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0403024 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0402873 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0394138 |
| VEGFA | vascular endothelial growth factor A | 0.0391388 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0385922 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355271 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.035055 |
| INHBA | inhibin, beta A | 0.0339076 |
| ATP13A3 | ATPase type 13A3 | 0.0338031 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0336109 |
| FMNL2 | formin-like 2 | 0.0322174 |
| CDH13 | cadherin 13 | 0.0309657 |
| COL5A3 | collagen, type V, alpha 3 | 0.030792 |
| XPO1 | exportin 1 | 0.0301589 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0293216 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0291576 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0288805 |
| CADM1 | cell adhesion molecule 1 | 0.0283823 |
| TMEM178B | transmembrane protein 178B | 0.027615 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0274458 |
| ZNF148 | zinc finger protein 148 | 0.0274187 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0268496 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0265342 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.026278 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0260895 |
| FNIP1 | folliculin interacting protein 1 | 0.0250145 |
| NAV1 | neuron navigator 1 | 0.0249897 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0247386 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0240147 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0238159 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0236486 |
| DST | dystonin | 0.0235643 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0235446 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0234959 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0234927 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0233536 |
| SETD5 | SET domain containing 5 | 0.0232748 |
| MSN | moesin | 0.0229564 |
| HLA-A | major histocompatibility complex, class I, A | 0.0226369 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0224833 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.022335 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223274 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0222994 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221614 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0219576 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0218463 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0216482 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0216065 |
| RYBP | RING1 and YY1 binding protein | 0.0215378 |
| SUCO | SUN domain containing ossification factor | 0.0214991 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.021459 |
| ITSN2 | intersectin 2 | 0.0213461 |
| RAI14 | retinoic acid induced 14 | 0.0212824 |
| INSIG2 | insulin induced gene 2 | 0.0211752 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0211334 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0208511 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0207837 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0207721 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0206234 |
| TMF1 | TATA element modulatory factor 1 | 0.0205956 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0205928 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0202685 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0202152 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0201148 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0200049 |
| CUX1 | cut-like homeobox 1 | 0.0199649 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0195514 |
| NGLY1 | N-glycanase 1 | 0.019388 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.019159 |
| BRD2 | bromodomain containing 2 | 0.0189304 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0187919 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0186993 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0184947 |
| HELZ | helicase with zinc finger | 0.018345 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.01825 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0182088 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0180128 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0177973 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0177638 |
| RND3 | Rho family GTPase 3 | 0.0176863 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0176485 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0173922 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0173647 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213266 |
| FN1 | fibronectin 1 | -0.198172 |
| VIM | vimentin | -0.189406 |
| NDRG1 | N-myc downstream regulated 1 | -0.157862 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139731 |
| CD44 | CD44 molecule (Indian blood group) | -0.10345 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0772223 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0746273 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0674904 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0589568 |
| POTEF | POTE ankyrin domain family, member F | -0.0585542 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0582894 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0556187 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.055532 |
| MT2A | metallothionein 2A | -0.0524162 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0519883 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0510621 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0509288 |
| RPLP1 | ribosomal protein, large, P1 | -0.0467772 |
| LDHA | lactate dehydrogenase A | -0.043672 |
| STC1 | stanniocalcin 1 | -0.0425557 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0409956 |
| ANXA2 | annexin A2 | -0.0408815 |
| PKM | pyruvate kinase, muscle | -0.0403875 |
| CENPF | centromere protein F, 350/400kDa | -0.040239 |
| RRBP1 | ribosome binding protein 1 | -0.0386205 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0373777 |
| TPM1 | tropomyosin 1 (alpha) | -0.0369409 |
| CDCP1 | CUB domain containing protein 1 | -0.0363351 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0358503 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0355962 |
| CENPE | centromere protein E, 312kDa | -0.0352864 |
| AHNAK | AHNAK nucleoprotein | -0.034748 |
| H1-0 | H1.0 linker histone | -0.0337316 |
| GNAS | GNAS complex locus | -0.0334117 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325973 |
| ARF1 | ADP-ribosylation factor 1 | -0.0317837 |
| TUBB | tubulin, beta class I | -0.0313138 |
| AFAP1 | actin filament associated protein 1 | -0.0309938 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0304464 |
| NAV2 | neuron navigator 2 | -0.0303646 |
| FRMD4A | FERM domain containing 4A | -0.0297217 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.029455 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0292557 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0286434 |
| HMGB1 | high mobility group box 1 | -0.0284377 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0281722 |
| S100A6 | S100 calcium binding protein A6 | -0.0278747 |
| RPS8 | ribosomal protein S8 | -0.0273648 |
| ZNF292 | zinc finger protein 292 | -0.0269278 |
| MKI67 | marker of proliferation Ki-67 | -0.0268952 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0268121 |
| FHIT | fragile histidine triad | -0.0267617 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0266765 |
| FAM20C | family with sequence similarity 20, member C | -0.026376 |
| HM13 | histocompatibility (minor) 13 | -0.0254794 |
| TPX2 | TPX2, microtubule-associated | -0.0250034 |
| RTN4 | reticulon 4 | -0.0249345 |
| HDLBP | high density lipoprotein binding protein | -0.0245997 |
| DIAPH3 | diaphanous-related formin 3 | -0.0245497 |
| TPI1 | triosephosphate isomerase 1 | -0.0244958 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0242654 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0241976 |
| TAGLN2 | transgelin 2 | -0.0237046 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0234421 |
| ACTN4 | actinin, alpha 4 | -0.0234037 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.023326 |
| SMAD3 | SMAD family member 3 | -0.0232819 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0231769 |
| RPS19 | ribosomal protein S19 | -0.0231532 |
| RPL35A | ribosomal protein L35a | -0.0229591 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0228469 |
| KLF6 | Kruppel-like factor 6 | -0.0228077 |
| MORF4L2 | mortality factor 4 like 2 | -0.0228002 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0227338 |
| NPAS2 | neuronal PAS domain protein 2 | -0.02264 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0225393 |
| TP63 | tumor protein p63 | -0.0224382 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0224364 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0224169 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0222137 |
| THBS1 | thrombospondin 1 | -0.0221875 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0219634 |
| HMGB2 | high mobility group box 2 | -0.0216512 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0216327 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0215046 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0213653 |
| MX2 | MX dynamin-like GTPase 2 | -0.0213527 |
| HMGA1 | high mobility group AT-hook 1 | -0.0211687 |
| PRNP | prion protein | -0.0211557 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0207917 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.020515 |
| YBX1 | Y box binding protein 1 | -0.0201619 |
| ETV5 | ets variant 5 | -0.0201114 |
| AOPEP | aminopeptidase O (putative) | -0.0200442 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0200412 |
| AFDN | afadin, adherens junction formation factor | -0.0200208 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0194683 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.019454 |
| SDCBP | syndecan binding protein (syntenin) | -0.0194197 |
