| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | 0.0615108 |
| MCL1 | myeloid cell leukemia 1 | 0.0572179 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0511527 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0478999 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0475968 |
| CHGB | chromogranin B | 0.044987 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0437107 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0423707 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0419624 |
| VGF | VGF nerve growth factor inducible | 0.0412571 |
| STC1 | stanniocalcin 1 | 0.040416 |
| RORA | RAR-related orphan receptor A | 0.0394923 |
| TMSB4X | thymosin beta 4, X-linked | 0.0361827 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0349251 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0348632 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.034661 |
| PGK1 | phosphoglycerate kinase 1 | 0.0346286 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0344332 |
| NDRG1 | N-myc downstream regulated 1 | 0.0330501 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0330199 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0329753 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0323442 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0317 |
| INHBA | inhibin, beta A | 0.0305167 |
| COPA | coatomer protein complex, subunit alpha | 0.0294404 |
| FAM13A | family with sequence similarity 13, member A | 0.0293474 |
| CRY1 | cryptochrome circadian clock 1 | 0.0291718 |
| APP | amyloid beta (A4) precursor protein | 0.0287159 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0284279 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0283426 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0276706 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0274325 |
| PCBP3 | poly(rC) binding protein 3 | 0.0272983 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0263536 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0261794 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0258264 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0255682 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0251481 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0248193 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0246633 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0245649 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0243868 |
| KIF26B | kinesin family member 26B | 0.0242976 |
| GPATCH2L | G patch domain containing 2-like | 0.0235446 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0225195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0223938 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0223282 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0222802 |
| PTCHD4 | patched domain containing 4 | 0.0218243 |
| SNTG1 | syntrophin, gamma 1 | 0.0215785 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.02147 |
| TSPYL2 | TSPY-like 2 | 0.0212207 |
| NRG1 | neuregulin 1 | 0.020533 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0204685 |
| ESRRG | estrogen-related receptor gamma | 0.0202808 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0202564 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0201387 |
| FNIP1 | folliculin interacting protein 1 | 0.0200175 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0198736 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0198442 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0198294 |
| PAPOLA | poly(A) polymerase alpha | 0.0198078 |
| NINL | ninein-like | 0.0197244 |
| PTK2 | protein tyrosine kinase 2 | 0.0196261 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196098 |
| CCNY | cyclin Y | 0.0194859 |
| RIMBP2 | RIMS binding protein 2 | 0.019131 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0191079 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.019089 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.018836 |
| VEGFA | vascular endothelial growth factor A | 0.0187474 |
| JAM3 | junctional adhesion molecule 3 | 0.0186661 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0186515 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0186496 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0183594 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0183499 |
| ARGLU1 | arginine and glutamate rich 1 | 0.018106 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0180393 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0177583 |
| RBM39 | RNA binding motif protein 39 | 0.0176822 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0176658 |
| NELL1 | NEL-like 1 (chicken) | 0.0175965 |
| B2M | beta-2-microglobulin | 0.0175039 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0174929 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.017477 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0174511 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0174249 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0172566 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0172233 |
| MED13L | mediator complex subunit 13-like | 0.0171291 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0169364 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0168585 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0166734 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0165778 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0165716 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0165453 |
| TOP3A | topoisomerase (DNA) III alpha | 0.0163838 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0163672 |
| YTHDC1 | YTH domain containing 1 | 0.0163259 |
| TPP2 | tripeptidyl peptidase II | 0.0160425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.192198 |
| TENM1 | teneurin transmembrane protein 1 | -0.155184 |
| PDE10A | phosphodiesterase 10A | -0.133522 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12297 |
| PTMA | prothymosin, alpha | -0.117611 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0832047 |
| FTL | ferritin, light polypeptide | -0.0766222 |
| CALCA | calcitonin-related polypeptide alpha | -0.0690553 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0629378 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0627081 |
| TXNRD1 | thioredoxin reductase 1 | -0.0565804 |
| CENPF | centromere protein F, 350/400kDa | -0.0559833 |
| POTEF | POTE ankyrin domain family, member F | -0.0558335 |
| RPS6 | ribosomal protein S6 | -0.0503933 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0495205 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0484393 |
| LOC112694756 | uncharaterized LOC112694756 | -0.048196 |
| NCKAP5 | NCK-associated protein 5 | -0.046771 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0445766 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0443188 |
| PEG10 | paternally expressed 10 | -0.0441224 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.043446 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0425573 |
| ACTG1 | actin gamma 1 | -0.0418511 |
| RPL8 | ribosomal protein L8 | -0.0405337 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0400202 |
| WWOX | WW domain containing oxidoreductase | -0.0396967 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0395485 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0390872 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0380105 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0379418 |
| RNF213 | ring finger protein 213 | -0.0376717 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0376117 |
| GPHN | gephyrin | -0.0373015 |
| RPS8 | ribosomal protein S8 | -0.0360359 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0359063 |
| RPL23 | ribosomal protein L23 | -0.0352502 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0350269 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0344735 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0342816 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0340568 |
| TUBB | tubulin, beta class I | -0.0337842 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0335229 |
| RAD51B | RAD51 paralog B | -0.0325028 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0324401 |
| PCBP2 | poly(rC) binding protein 2 | -0.0319397 |
| TOX | thymocyte selection-associated high mobility group box | -0.0316866 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0314554 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0314396 |
| FAM162A | family with sequence similarity 162, member A | -0.0311219 |
| NRXN1 | neurexin 1 | -0.0309146 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0308076 |
| RPS19 | ribosomal protein S19 | -0.0307541 |
| SYT1 | synaptotagmin I | -0.0300409 |
| RPL7 | ribosomal protein L7 | -0.0293113 |
| FOXP1 | forkhead box P1 | -0.0291741 |
| PKM | pyruvate kinase, muscle | -0.0288937 |
| RTN4 | reticulon 4 | -0.0287783 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0286413 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284269 |
| NLGN1 | neuroligin 1 | -0.0282427 |
| MKI67 | marker of proliferation Ki-67 | -0.0278741 |
| RPL19 | ribosomal protein L19 | -0.0278008 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274939 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0274179 |
| UBB | ubiquitin B | -0.0273431 |
| LDHA | lactate dehydrogenase A | -0.027199 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0270994 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0269884 |
| RPL11 | ribosomal protein L11 | -0.026948 |
| H1-0 | H1.0 linker histone | -0.0268514 |
| TRIM9 | tripartite motif containing 9 | -0.0266056 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0263751 |
| MAP1B | microtubule-associated protein 1B | -0.026137 |
| RPLP0 | ribosomal protein, large, P0 | -0.0252728 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0247467 |
| ADAR | adenosine deaminase, RNA-specific | -0.0247051 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0246882 |
| TUBA1B | tubulin, alpha 1b | -0.0243726 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0240575 |
| CADM1 | cell adhesion molecule 1 | -0.0239496 |
| KIAA0825 | KIAA0825 | -0.0235007 |
| RPS27 | ribosomal protein S27 | -0.0234616 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0234199 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233979 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0233112 |
| UBC | ubiquitin C | -0.023085 |
| RPS27A | ribosomal protein S27a | -0.0227364 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0226372 |
| HMGB1 | high mobility group box 1 | -0.0225745 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0223876 |
| SEPTIN7 | septin 7 | -0.0221467 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0220807 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.021893 |
| RPS25 | ribosomal protein S25 | -0.0218487 |
| RIGI | RNA sensor RIG-I | -0.0218282 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0214258 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0213859 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0213248 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0212235 |
