| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.065507 |
| FMNL2 | formin-like 2 | 0.0594754 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0449337 |
| SPAG9 | sperm associated antigen 9 | 0.0414049 |
| HELZ | helicase with zinc finger | 0.0371103 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0366014 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0359329 |
| MMP12 | matrix metallopeptidase 12 | 0.034791 |
| GOLGA4 | golgin A4 | 0.0341336 |
| MSI2 | musashi RNA-binding protein 2 | 0.0337807 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.029405 |
| CADM1 | cell adhesion molecule 1 | 0.0288986 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0283482 |
| NGLY1 | N-glycanase 1 | 0.0279005 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0273527 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0272659 |
| OGA | O-GlcNAcase | 0.026314 |
| TENM1 | teneurin transmembrane protein 1 | 0.0257808 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0238342 |
| PHF21A | PHD finger protein 21A | 0.0225482 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0216906 |
| FAM13A | family with sequence similarity 13, member A | 0.0214647 |
| CD109 | CD109 molecule | 0.0204796 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0204563 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0203404 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0201606 |
| RYBP | RING1 and YY1 binding protein | 0.0199589 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0195499 |
| VEGFA | vascular endothelial growth factor A | 0.0194813 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0193759 |
| ZNF654 | zinc finger protein 654 | 0.0191676 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0190222 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0188711 |
| SNX14 | sorting nexin 14 | 0.0185708 |
| SETD5 | SET domain containing 5 | 0.0185222 |
| CUL3 | cullin 3 | 0.0184771 |
| MLF1 | myeloid leukemia factor 1 | 0.0183886 |
| RLF | rearranged L-myc fusion | 0.0183155 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0177699 |
| ATP13A3 | ATPase type 13A3 | 0.0177068 |
| USP3 | ubiquitin specific peptidase 3 | 0.0173079 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0172235 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0171626 |
| CCDC47 | coiled-coil domain containing 47 | 0.0170935 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0170216 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0169125 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0167886 |
| RNF145 | ring finger protein 145 | 0.0167642 |
| MEF2A | myocyte enhancer factor 2A | 0.0165414 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0163681 |
| ARRDC3 | arrestin domain containing 3 | 0.016246 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0158719 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0158578 |
| FOXJ3 | forkhead box J3 | 0.0158247 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0157287 |
| RAB18 | RAB18, member RAS oncogene family | 0.015715 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0157083 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.015673 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0156484 |
| ZNF292 | zinc finger protein 292 | 0.0155297 |
| ANGPTL4 | angiopoietin-like 4 | 0.0155226 |
| ETNK1 | ethanolamine kinase 1 | 0.0154515 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0152887 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0152728 |
| CEP95 | centrosomal protein 95kDa | 0.0149831 |
| SEC24A | SEC24 family member A | 0.0149372 |
| KLHL24 | kelch-like family member 24 | 0.0149353 |
| CDK19 | cyclin-dependent kinase 19 | 0.0148863 |
| ABI1 | abl-interactor 1 | 0.0147399 |
| FOXO3 | forkhead box O3 | 0.0145482 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0145098 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0144854 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0143695 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0141733 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0141436 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0141363 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.01405 |
| TRIM2 | tripartite motif containing 2 | 0.0139036 |
| PCBP3 | poly(rC) binding protein 3 | 0.0138036 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0134909 |
| FOXN3 | forkhead box N3 | 0.0134182 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0134005 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0133928 |
| RPL14 | ribosomal protein L14 | 0.0133869 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0133336 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0131513 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0131155 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0130936 |
| CEP70 | centrosomal protein 70kDa | 0.0130431 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0130429 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.012958 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0129542 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0129306 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.012892 |
| ANK2 | ankyrin 2, neuronal | 0.0128427 |
| COPA | coatomer protein complex, subunit alpha | 0.0128398 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0128053 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0126566 |
| SKP1 | S-phase kinase-associated protein 1 | 0.012431 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0124037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.149281 |
| VIM | vimentin | -0.146077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13246 |
| FN1 | fibronectin 1 | -0.108307 |
| FRMD4A | FERM domain containing 4A | -0.100501 |
| CCND1 | cyclin D1 | -0.0874233 |
| FMN1 | formin 1 | -0.0790919 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0765508 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.064314 |
| POTEF | POTE ankyrin domain family, member F | -0.0568977 |
| RPS3 | ribosomal protein S3 | -0.0568058 |
| ENO1 | enolase 1, (alpha) | -0.0567866 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.055083 |
| LSAMP | limbic system-associated membrane protein | -0.0539404 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0533226 |
| UBC | ubiquitin C | -0.0511305 |
| HDAC9 | histone deacetylase 9 | -0.0501785 |
| NLGN1 | neuroligin 1 | -0.0499604 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0494506 |
| FRMD5 | FERM domain containing 5 | -0.047279 |
| SQSTM1 | sequestosome 1 | -0.0463691 |
| CDK6 | cyclin-dependent kinase 6 | -0.0457307 |
| RUNX1 | runt-related transcription factor 1 | -0.0442586 |
| TMSB10 | thymosin beta 10 | -0.0440845 |
| CD44 | CD44 molecule (Indian blood group) | -0.042383 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0420631 |
| RNF213 | ring finger protein 213 | -0.0405011 |
| RPL23 | ribosomal protein L23 | -0.0395347 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0383292 |
| FLNA | filamin A, alpha | -0.0380755 |
| TXNRD1 | thioredoxin reductase 1 | -0.0374715 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0371621 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0370715 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0370196 |
| MT2A | metallothionein 2A | -0.0358621 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0355132 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0347998 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0338292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336113 |
| RPS6 | ribosomal protein S6 | -0.0334245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.033271 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0316933 |
| PKM | pyruvate kinase, muscle | -0.0314089 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0310549 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0299752 |
| RAD51B | RAD51 paralog B | -0.0296291 |
| ACTG1 | actin gamma 1 | -0.0293133 |
| RPS27A | ribosomal protein S27a | -0.0289179 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283127 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028084 |
| LAMB1 | laminin, beta 1 | -0.0277275 |
| NAV2 | neuron navigator 2 | -0.0276862 |
| FTL | ferritin, light polypeptide | -0.0275804 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0264996 |
| RACK1 | receptor for activated C kinase 1 | -0.0262514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260551 |
| MAP4 | microtubule-associated protein 4 | -0.026007 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0259685 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0256281 |
| RASAL2 | RAS protein activator like 2 | -0.0254526 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0247506 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0247071 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0246971 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0246813 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0245573 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0244085 |
| NRG3 | neuregulin 3 | -0.0240188 |
| APOD | apolipoprotein D | -0.0239936 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0237419 |
| ACTN4 | actinin, alpha 4 | -0.023668 |
| EXOC4 | exocyst complex component 4 | -0.023643 |
| CDH13 | cadherin 13 | -0.0235982 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0235775 |
| HMGA1 | high mobility group AT-hook 1 | -0.0234741 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0231256 |
| TPI1 | triosephosphate isomerase 1 | -0.0230173 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0227758 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0227406 |
| RPL35A | ribosomal protein L35a | -0.0226994 |
| TNNC1 | troponin C type 1 (slow) | -0.0222797 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.022277 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0220912 |
| ETV6 | ets variant 6 | -0.0215726 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0214277 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0213461 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.021298 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0212869 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0211561 |
| ACTN1 | actinin, alpha 1 | -0.021062 |
| RPS4X | ribosomal protein S4, X-linked | -0.0210012 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0209688 |
| HDAC8 | histone deacetylase 8 | -0.0209263 |
| TENM3 | teneurin transmembrane protein 3 | -0.0209237 |
| AHNAK | AHNAK nucleoprotein | -0.0208736 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.020703 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0205819 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0201056 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0200988 |
| PCBP2 | poly(rC) binding protein 2 | -0.0197788 |
| SMYD3 | SET and MYND domain containing 3 | -0.0196393 |
