Indacaterol (maleate)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Indacaterol (maleate) perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Indacaterol (maleate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TXNRD1 thioredoxin reductase 1 0.115183
GOLGA4 golgin A4 0.0819184
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0791637
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.077236
RTN4 reticulon 4 0.0744954
JMJD1C jumonji domain containing 1C 0.0719156
PTMA prothymosin, alpha 0.0717589
DSCAM Down syndrome cell adhesion molecule 0.0674406
TMSB4X thymosin beta 4, X-linked 0.066691
RBM25 RNA binding motif protein 25 0.0569734
EIF4A2 eukaryotic translation initiation factor 4A2 0.054821
RPS6 ribosomal protein S6 0.0532445
B2M beta-2-microglobulin 0.05307
S100A6 S100 calcium binding protein A6 0.0472851
OSMR oncostatin M receptor 0.0458796
ANK2 ankyrin 2, neuronal 0.0452336
ZFAND3 zinc finger, AN1-type domain 3 0.0437984
ADAM10 ADAM metallopeptidase domain 10 0.042921
PUM2 pumilio RNA-binding family member 2 0.0428826
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0424995
RBM39 RNA binding motif protein 39 0.0420744
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0407316
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0392254
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0391659
SLC38A2 solute carrier family 38, member 2 0.0386909
ZNF644 zinc finger protein 644 0.0386732
ELOVL5 ELOVL fatty acid elongase 5 0.0374586
VMP1 vacuole membrane protein 1 0.0374341
BRWD1 bromodomain and WD repeat domain containing 1 0.0373453
RB1CC1 RB1-inducible coiled-coil 1 0.0372696
SQSTM1 sequestosome 1 0.0363788
RUSC2 RUN and SH3 domain containing 2 0.0362898
NCEH1 neutral cholesterol ester hydrolase 1 0.0361689
AKAP9 A kinase (PRKA) anchor protein 9 0.0361534
MT2A metallothionein 2A 0.0361475
CHD1 chromodomain helicase DNA binding protein 1 0.0360811
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0357475
PNISR PNN-interacting serine/arginine-rich protein 0.0355958
PTBP2 polypyrimidine tract binding protein 2 0.0353669
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.0351696
EIF3A eukaryotic translation initiation factor 3, subunit A 0.034843
TJP1 tight junction protein 1 0.0346932
PCNX1 pecanex 1 0.0345435
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0338721
TMEM41B transmembrane protein 41B 0.0331969
GSK3B glycogen synthase kinase 3 beta 0.0330709
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.032766
SRSF11 serine/arginine-rich splicing factor 11 0.0323291
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0322386
KDM2A lysine (K)-specific demethylase 2A 0.031257
SEC23A Sec23 homolog A (S. cerevisiae) 0.0311978
CUL3 cullin 3 0.0311098
NQO1 NAD(P)H dehydrogenase, quinone 1 0.0309399
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.0307333
ADNP activity-dependent neuroprotector homeobox 0.0297531
CEP95 centrosomal protein 95kDa 0.0296551
MON2 MON2 homolog (S. cerevisiae) 0.0295808
RPS23 ribosomal protein S23 0.0293134
ANKRD12 ankyrin repeat domain 12 0.0290684
SSR1 signal sequence receptor, alpha 0.0282794
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0282744
TMEM65 transmembrane protein 65 0.0279539
ARF4 ADP-ribosylation factor 4 0.0278902
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.0278748
EFNA5 ephrin-A5 0.0277709
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0272372
PTEN phosphatase and tensin homolog 0.0266445
TTC3 tetratricopeptide repeat domain 3 0.0265194
TBC1D5 TBC1 domain family, member 5 0.0260625
POU2F1 POU class 2 homeobox 1 0.0258238
EIF4B eukaryotic translation initiation factor 4B 0.0258193
RPS12 ribosomal protein S12 0.0257063
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0256324
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0255349
WDR43 WD repeat domain 43 0.025274
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.0250991
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0250979
CLTC clathrin, heavy chain (Hc) 0.0250356
PYGB phosphorylase, glycogen; brain 0.0249471
FLNB filamin B, beta 0.024528
PLPP3 phospholipid phosphatase 3 0.0245084
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0241667
RPS3 ribosomal protein S3 0.0240263
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0238252
ETNK1 ethanolamine kinase 1 0.0237924
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0236602
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0236245
NKTR natural killer cell triggering receptor 0.0235357
ATXN1 ataxin 1 0.023156
TBK1 TANK-binding kinase 1 0.0230857
ZNHIT6 zinc finger, HIT-type containing 6 0.0230678
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0229854
COG6 component of oligomeric golgi complex 6 0.0229331
CYTH3 cytohesin 3 0.0228582
ZNF160 zinc finger protein 160 0.0228321
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0227785
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.0227367
BIRC6 baculoviral IAP repeat containing 6 0.0225986
TMF1 TATA element modulatory factor 1 0.0225503
EXT1 exostosin glycosyltransferase 1 0.0225497

decreased expression

Symbol Name Standardized Value
PDE4B phosphodiesterase 4B, cAMP-specific -0.154024
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0969941
BMP10 bone morphogenetic protein 10 -0.0907571
FOXP1 forkhead box P1 -0.0852448
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0787017
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0723837
AHNAK AHNAK nucleoprotein -0.0681838
NAV2 neuron navigator 2 -0.067358
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0636708
DLG1 discs, large homolog 1 (Drosophila) -0.0592611
PKM pyruvate kinase, muscle -0.0565257
GLI3 GLI family zinc finger 3 -0.0516044
ANXA1 annexin A1 -0.045501
SSBP2 single-stranded DNA binding protein 2 -0.0435272
NPAS2 neuronal PAS domain protein 2 -0.0413342
SMC4 structural maintenance of chromosomes 4 -0.041046
RFC3 replication factor C (activator 1) 3, 38kDa -0.0408259
MKI67 marker of proliferation Ki-67 -0.0400852
PRUNE2 prune homolog 2 (Drosophila) -0.0382028
DIAPH3 diaphanous-related formin 3 -0.037806
MYO5C myosin VC -0.0367917
BMP2K BMP2 inducible kinase -0.0366679
GLI2 GLI family zinc finger 2 -0.035451
SCLT1 sodium channel and clathrin linker 1 -0.0349629
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0333746
UNC13A unc-13 homolog A (C. elegans) -0.032661
HSPB1 heat shock 27kDa protein 1 -0.0326185
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0324474
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0315719
HDAC9 histone deacetylase 9 -0.0309959
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0301458
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0298513
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0298277
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.029555
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0290926
CUX1 cut-like homeobox 1 -0.028866
HJURP Holliday junction recognition protein -0.0283488
RAD18 RAD18 E3 ubiquitin protein ligase -0.0281526
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0280975
EGFR epidermal growth factor receptor -0.0275367
KDM3A lysine (K)-specific demethylase 3A -0.0275028
SOX6 SRY (sex determining region Y)-box 6 -0.0270813
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0270035
CAMKMT calmodulin-lysine N-methyltransferase -0.0269444
LPP LIM domain containing preferred translocation partner in lipoma -0.0265467
CENPF centromere protein F, 350/400kDa -0.0258211
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0258199
PDE7B phosphodiesterase 7B -0.0253486
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.0252129
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0247404
ECT2 epithelial cell transforming 2 -0.0243121
DPYD dihydropyrimidine dehydrogenase -0.0242267
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0242232
ENO1 enolase 1, (alpha) -0.0236703
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0236434
RLF rearranged L-myc fusion -0.0234947
INTS6 integrator complex subunit 6 -0.0232267
TUBB4B tubulin, beta 4B class IVb -0.0230663
MSI2 musashi RNA-binding protein 2 -0.021767
ATXN2 ataxin 2 -0.0214487
CENPE centromere protein E, 312kDa -0.0212004
LRRC7 leucine rich repeat containing 7 -0.0209375
ASXL2 additional sex combs like transcriptional regulator 2 -0.020781
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0206074
PRKCE protein kinase C, epsilon -0.0204313
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0203076
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0201123
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0200429
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0199675
EMP3 epithelial membrane protein 3 -0.0197998
RRM2 ribonucleotide reductase M2 -0.0196831
PRELID2 PRELI domain containing 2 -0.0196807
PDIA6 protein disulfide isomerase family A, member 6 -0.0196603
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0196577
ITGA10 integrin, alpha 10 -0.0193156
PHACTR2 phosphatase and actin regulator 2 -0.0192598
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0189508
WWOX WW domain containing oxidoreductase -0.0184909
EML4 echinoderm microtubule associated protein like 4 -0.0184907
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0184833
PKP4 plakophilin 4 -0.0184098
BCL2 B-cell CLL/lymphoma 2 -0.0183682
TUBA1B tubulin, alpha 1b -0.0182917
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.0181073
COMMD10 COMM domain containing 10 -0.0179308
ATOSA atos homolog A -0.0178936
ITGA6 integrin, alpha 6 -0.0178309
NEBL nebulette -0.0178091
LOC112694756 uncharaterized LOC112694756 -0.0176749
FMNL2 formin-like 2 -0.0176607
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0174901
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0173801
WSB1 WD repeat and SOCS box containing 1 -0.0172914
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.0172489
TM4SF1 transmembrane 4 L six family member 1 -0.0172238
PDIA3 protein disulfide isomerase family A, member 3 -0.0171692
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.0170459
IRS1 insulin receptor substrate 1 -0.0169225
MMS22L MMS22-like, DNA repair protein -0.0168355
SOGA1 suppressor of glucose, autophagy associated 1 -0.0165521