| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.120526 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0653153 |
| B2M | beta-2-microglobulin | 0.0619633 |
| NRXN3 | neurexin 3 | 0.0570828 |
| VEGFA | vascular endothelial growth factor A | 0.0513238 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0465619 |
| FNIP1 | folliculin interacting protein 1 | 0.0462654 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0454529 |
| EFNA5 | ephrin-A5 | 0.0411614 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0366899 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0365802 |
| DST | dystonin | 0.0334873 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0324754 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0320729 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0318818 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0308036 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0306182 |
| SBF2 | SET binding factor 2 | 0.0305881 |
| CMIP | c-Maf inducing protein | 0.0305752 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0304255 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0301457 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0299777 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0297978 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0297714 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0294184 |
| FAM13A | family with sequence similarity 13, member A | 0.029212 |
| MED13L | mediator complex subunit 13-like | 0.0291636 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0289189 |
| RAD51B | RAD51 paralog B | 0.0280699 |
| NBAS | neuroblastoma amplified sequence | 0.0277545 |
| CLIC4 | chloride intracellular channel 4 | 0.0274156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0273961 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.027297 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0272833 |
| PRELID2 | PRELI domain containing 2 | 0.0268753 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0263689 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0261724 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0257927 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0257638 |
| GLRX | glutaredoxin (thioltransferase) | 0.0254075 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.025262 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0250884 |
| CDH13 | cadherin 13 | 0.0249557 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0249075 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0248314 |
| PCNX1 | pecanex 1 | 0.0246862 |
| RIN2 | Ras and Rab interactor 2 | 0.024009 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0239775 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0237731 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0231312 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0231223 |
| FAM13B | family with sequence similarity 13, member B | 0.0229934 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0229415 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227374 |
| NBEAL1 | neurobeachin-like 1 | 0.0226791 |
| XPO1 | exportin 1 | 0.02253 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0222529 |
| KAZN | kazrin, periplakin interacting protein | 0.0219216 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0218655 |
| NAV1 | neuron navigator 1 | 0.0217829 |
| EGFR | epidermal growth factor receptor | 0.0217335 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0216497 |
| ZNF146 | zinc finger protein 146 | 0.0215483 |
| SNX9 | sorting nexin 9 | 0.0213897 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0212094 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0211 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0208279 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0207871 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0207186 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0207103 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203528 |
| TMEM167A | transmembrane protein 167A | 0.0203475 |
| TMEM165 | transmembrane protein 165 | 0.0202863 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201792 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0200965 |
| TNS3 | tensin 3 | 0.0200773 |
| JAK1 | Janus kinase 1 | 0.0200725 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0199932 |
| FMNL2 | formin-like 2 | 0.0198552 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0197309 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0195286 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0195069 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0194676 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0194559 |
| COG6 | component of oligomeric golgi complex 6 | 0.0193878 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0193659 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0193102 |
| PRKCA | protein kinase C, alpha | 0.0192813 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0191823 |
| YAP1 | Yes-associated protein 1 | 0.0191726 |
| NF1 | neurofibromin 1 | 0.019058 |
| RANBP9 | RAN binding protein 9 | 0.0190537 |
| PHF21A | PHD finger protein 21A | 0.0190219 |
| MYO1E | myosin IE | 0.0189278 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0189189 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0189161 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0188882 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.018776 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0187374 |
| INTS6 | integrator complex subunit 6 | 0.0187234 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.288901 |
| TMSB10 | thymosin beta 10 | -0.212137 |
| COL6A3 | collagen, type VI, alpha 3 | -0.175513 |
| MT2A | metallothionein 2A | -0.131371 |
| VIM | vimentin | -0.119776 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.118164 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.107388 |
| HLA-B | major histocompatibility complex, class I, B | -0.095731 |
| UBC | ubiquitin C | -0.0789777 |
| AHNAK | AHNAK nucleoprotein | -0.0704773 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0641653 |
| SDC4 | syndecan 4 | -0.0626716 |
| TXNIP | thioredoxin interacting protein | -0.0608461 |
| PTMA | prothymosin, alpha | -0.0599206 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0572238 |
| ANXA2 | annexin A2 | -0.056883 |
| CALU | calumenin | -0.0548179 |
| SRPK2 | SRSF protein kinase 2 | -0.0547482 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.054691 |
| FN1 | fibronectin 1 | -0.0513813 |
| SMAD3 | SMAD family member 3 | -0.0446945 |
| ENO1 | enolase 1, (alpha) | -0.0427582 |
| COL1A1 | collagen, type I, alpha 1 | -0.04223 |
| NDRG1 | N-myc downstream regulated 1 | -0.0416584 |
| WTAP | Wilms tumor 1 associated protein | -0.0414281 |
| FTL | ferritin, light polypeptide | -0.0412141 |
| LDHA | lactate dehydrogenase A | -0.0407451 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0406101 |
| COL1A2 | collagen, type I, alpha 2 | -0.0399248 |
| H3-3B | H3.3 histone B | -0.0392755 |
| LOXL2 | lysyl oxidase-like 2 | -0.0383782 |
| TAGLN2 | transgelin 2 | -0.0377825 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0376372 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0370207 |
| CALD1 | caldesmon 1 | -0.0365678 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0365524 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0362631 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0356536 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0353345 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0352313 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0350848 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0344682 |
| CLTC | clathrin, heavy chain (Hc) | -0.0343543 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0338038 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0335623 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.033361 |
| GANAB | glucosidase, alpha; neutral AB | -0.0330869 |
| FLNA | filamin A, alpha | -0.0329289 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0328543 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.032313 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0321165 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0319341 |
| RPLP1 | ribosomal protein, large, P1 | -0.031783 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0317174 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0315152 |
| RAB10 | RAB10, member RAS oncogene family | -0.0303569 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0301421 |
| USP34 | ubiquitin specific peptidase 34 | -0.0300726 |
| CD44 | CD44 molecule (Indian blood group) | -0.0298987 |
| CDK6 | cyclin-dependent kinase 6 | -0.0298828 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0298728 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0295456 |
| SPAG9 | sperm associated antigen 9 | -0.0294707 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0292958 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0286775 |
| TPM4 | tropomyosin 4 | -0.0281831 |
| CCNI | cyclin I | -0.0275945 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0274794 |
| RUNX2 | runt-related transcription factor 2 | -0.0274634 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0273692 |
| ANKRD12 | ankyrin repeat domain 12 | -0.027201 |
| RBM25 | RNA binding motif protein 25 | -0.0270093 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0268413 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0266719 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266061 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0265668 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0265466 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0264027 |
| RLIM | ring finger protein, LIM domain interacting | -0.0261606 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0261446 |
| ANXA5 | annexin A5 | -0.0261173 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0261065 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.025817 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0256106 |
| FAT1 | FAT atypical cadherin 1 | -0.0254999 |
| EXOC4 | exocyst complex component 4 | -0.0253494 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0252932 |
| ZNF609 | zinc finger protein 609 | -0.025136 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0250324 |
| SFTPA2 | surfactant protein A2 | -0.0248693 |
| RTN4 | reticulon 4 | -0.0244062 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0242206 |
| RPS27A | ribosomal protein S27a | -0.0242042 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0241521 |
| ECE1 | endothelin converting enzyme 1 | -0.0240994 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.024062 |
| TPR | translocated promoter region, nuclear basket protein | -0.0239499 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0238499 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0238097 |
| AHR | aryl hydrocarbon receptor | -0.0237602 |