Indacaterol (maleate)_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Indacaterol (maleate) perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Indacaterol (maleate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SPAG9 sperm associated antigen 9 0.0764037
WAC WW domain containing adaptor with coiled-coil 0.0624519
SETD5 SET domain containing 5 0.0605742
TRA2A transformer 2 alpha homolog (Drosophila) 0.0577142
KMT2E lysine (K)-specific methyltransferase 2E 0.0558772
CAPRIN2 caprin family member 2 0.0557348
RBM39 RNA binding motif protein 39 0.0546883
TFG TRK-fused gene 0.0544515
FMNL2 formin-like 2 0.0491337
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0481147
TOP2B topoisomerase (DNA) II beta 180kDa 0.0448001
BCLAF1 BCL2-associated transcription factor 1 0.0438312
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0433613
FXR1 fragile X mental retardation, autosomal homolog 1 0.0430685
OGA O-GlcNAcase 0.0429179
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0426415
QKI QKI, KH domain containing, RNA binding 0.0412694
GPBP1 GC-rich promoter binding protein 1 0.0393826
ASXL1 additional sex combs like transcriptional regulator 1 0.0390738
HELZ helicase with zinc finger 0.0379279
KDM6A lysine (K)-specific demethylase 6A 0.0378272
ZNF292 zinc finger protein 292 0.0367706
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0366274
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0366096
RNF145 ring finger protein 145 0.0361313
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0356343
NAP1L1 nucleosome assembly protein 1-like 1 0.0353049
MARCHF6 membrane associated ring-CH-type finger 6 0.0352393
PDS5B PDS5 cohesin associated factor B 0.0351401
AHCTF1 AT hook containing transcription factor 1 0.0346044
PTK2 protein tyrosine kinase 2 0.0345069
TXNRD1 thioredoxin reductase 1 0.0345
GOLGA2 golgin A2 0.0343516
KTN1 kinectin 1 (kinesin receptor) 0.0339946
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0338647
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0337663
UBA6 ubiquitin-like modifier activating enzyme 6 0.03275
ATP13A3 ATPase type 13A3 0.032194
RAB6A RAB6A, member RAS oncogene family 0.0321771
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0321473
COG5 component of oligomeric golgi complex 5 0.0320431
NUP58 nucleoporin 58 0.0320083
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0318485
HILPDA hypoxia inducible lipid droplet-associated 0.0317432
PUM1 pumilio RNA-binding family member 1 0.0315454
PDGFA platelet-derived growth factor alpha polypeptide 0.0314992
TSC22D2 TSC22 domain family, member 2 0.0313225
MORF4L1 mortality factor 4 like 1 0.0312819
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0308133
SNX14 sorting nexin 14 0.0307201
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0306887
KLHL24 kelch-like family member 24 0.0306478
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0306201
WDR43 WD repeat domain 43 0.0299848
RSRC2 arginine/serine-rich coiled-coil 2 0.0299582
CUL3 cullin 3 0.0298159
NPEPPS aminopeptidase puromycin sensitive 0.0294489
GOLT1B golgi transport 1B 0.0293556
KMT2C lysine (K)-specific methyltransferase 2C 0.0291694
NOP58 NOP58 ribonucleoprotein 0.0290232
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0289914
XPO1 exportin 1 0.0289329
PAWR PRKC, apoptosis, WT1, regulator 0.0287361
ANKRD11 ankyrin repeat domain 11 0.0284744
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0284326
SEC23A Sec23 homolog A (S. cerevisiae) 0.0284001
CRY1 cryptochrome circadian clock 1 0.0283994
YAP1 Yes-associated protein 1 0.0281876
HBP1 HMG-box transcription factor 1 0.0281102
SET SET nuclear proto-oncogene 0.0278578
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0277659
RAD23B RAD23 homolog B (S. cerevisiae) 0.0277411
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.0276308
NBAS neuroblastoma amplified sequence 0.0276295
SEC24D SEC24 family member D 0.0274276
SEC24A SEC24 family member A 0.0271897
GOLGA4 golgin A4 0.0271479
DGKD diacylglycerol kinase, delta 130kDa 0.026836
SCAF11 SR-related CTD-associated factor 11 0.0267322
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.0267024
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0265384
SDC4 syndecan 4 0.026524
CCDC93 coiled-coil domain containing 93 0.026454
FAM193A family with sequence similarity 193, member A 0.0263473
TMEM39A transmembrane protein 39A 0.0260244
SPDYA speedy/RINGO cell cycle regulator family member A 0.0258628
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0255706
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0255677
CHD1 chromodomain helicase DNA binding protein 1 0.0254943
SUCO SUN domain containing ossification factor 0.0254524
RPL14 ribosomal protein L14 0.025231
TPR translocated promoter region, nuclear basket protein 0.0252148
COPA coatomer protein complex, subunit alpha 0.0251872
MTMR3 myotubularin related protein 3 0.0251835
TOP1 topoisomerase (DNA) I 0.0250809
BRD2 bromodomain containing 2 0.0250694
TENT2 terminal nucleotidyltransferase 2 0.0250594
UGCG UDP-glucose ceramide glucosyltransferase 0.0249991
TM9SF2 transmembrane 9 superfamily member 2 0.0248141
RLF rearranged L-myc fusion 0.0247726

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.333729
VIM vimentin -0.153265
TMSB10 thymosin beta 10 -0.112732
LDHA lactate dehydrogenase A -0.0698553
RPL35A ribosomal protein L35a -0.0621544
LOC112694756 uncharaterized LOC112694756 -0.0619499
PTMA prothymosin, alpha -0.0583423
ZBTB20 zinc finger and BTB domain containing 20 -0.0567125
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0543778
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0540681
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0531604
TPT1 tumor protein, translationally-controlled 1 -0.0509785
DPYD dihydropyrimidine dehydrogenase -0.0486267
APOLD1 apolipoprotein L domain containing 1 -0.0480818
SMYD3 SET and MYND domain containing 3 -0.0476392
RPLP1 ribosomal protein, large, P1 -0.0468526
IGF2 insulin-like growth factor 2 -0.0462656
BPTF bromodomain PHD finger transcription factor -0.0446854
SLC38A2 solute carrier family 38, member 2 -0.0444923
CD44 CD44 molecule (Indian blood group) -0.0436557
AHNAK AHNAK nucleoprotein -0.0411188
ATXN1 ataxin 1 -0.0409673
NT5E 5'-nucleotidase, ecto (CD73) -0.0385945
ATG7 autophagy related 7 -0.0381108
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0376403
DNER delta/notch-like EGF repeat containing -0.03763
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0367739
SMC4 structural maintenance of chromosomes 4 -0.035752
FLNB filamin B, beta -0.0351597
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0349875
THSD4 thrombospondin, type I, domain containing 4 -0.0347703
ACTG1 actin gamma 1 -0.0345941
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0344881
FBXL7 F-box and leucine-rich repeat protein 7 -0.034257
OSMR oncostatin M receptor -0.0340942
GNAS GNAS complex locus -0.0337152
BRCA2 breast cancer 2, early onset -0.0331398
TPI1 triosephosphate isomerase 1 -0.0329428
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 -0.0328802
ATG10 autophagy related 10 -0.032646
HMGA2 high mobility group AT-hook 2 -0.0326081
IL1RAP interleukin 1 receptor accessory protein -0.0324602
TM4SF1 transmembrane 4 L six family member 1 -0.0318544
RPL23 ribosomal protein L23 -0.0318065
DLG1 discs, large homolog 1 (Drosophila) -0.031728
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.031723
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.0317014
MYO9A myosin IXA -0.0315505
MBD5 methyl-CpG binding domain protein 5 -0.0312137
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0307997
CANX calnexin -0.0305896
C6ORF62 chromosome 6 open reading frame 62 -0.0304562
PKM pyruvate kinase, muscle -0.0303242
BABAM2 BRISC and BRCA1 A complex member 2 -0.0302958
RPLP0 ribosomal protein, large, P0 -0.0301945
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0301681
ANLN anillin, actin binding protein -0.0301325
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0297321
KIF5B kinesin family member 5B -0.0296246
RNF213 ring finger protein 213 -0.0295254
DST dystonin -0.0294906
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0290515
NALCN sodium leak channel, non selective -0.0286537
PARD3 par-3 family cell polarity regulator -0.0281122
SGO2 shugoshin 2 -0.0280649
TNRC6B trinucleotide repeat containing 6B -0.0279178
HDAC9 histone deacetylase 9 -0.0278328
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0275663
ZNF609 zinc finger protein 609 -0.0274462
PCNX4 pecanex 4 -0.0273619
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0272577
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0272453
TRIM56 tripartite motif containing 56 -0.0270607
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0270304
TAOK3 TAO kinase 3 -0.0270092
TNRC18 trinucleotide repeat containing 18 -0.0268613
TRIP12 thyroid hormone receptor interactor 12 -0.0267502
EFNA5 ephrin-A5 -0.0261839
PDE4D phosphodiesterase 4D, cAMP-specific -0.0259288
MYADM myeloid-associated differentiation marker -0.0258266
FNIP1 folliculin interacting protein 1 -0.0256862
ETV6 ets variant 6 -0.0254844
HLA-C major histocompatibility complex, class I, C -0.0253944
RSF1 remodeling and spacing factor 1 -0.025365
FMN1 formin 1 -0.0253267
FBXL17 F-box and leucine-rich repeat protein 17 -0.0253171
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0251878
BBS9 Bardet-Biedl syndrome 9 -0.0251001
WWOX WW domain containing oxidoreductase -0.0250948
RRBP1 ribosome binding protein 1 -0.0249951
TUBB4B tubulin, beta 4B class IVb -0.0248702
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0248191
PRH1 proline-rich protein HaeIII subfamily 1 -0.0246616
BASP1 brain abundant, membrane attached signal protein 1 -0.0246479
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.024438
EXOC4 exocyst complex component 4 -0.0244205
PRSS23 protease, serine, 23 -0.0243836
DIAPH3 diaphanous-related formin 3 -0.024372
RPLP2 ribosomal protein, large, P2 -0.0241134
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0239525