| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125328 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.10261 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0998695 |
| EZR | ezrin | 0.0927665 |
| KRT8 | keratin 8, type II | 0.0925687 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0868672 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0837826 |
| B2M | beta-2-microglobulin | 0.0805928 |
| TMSB4X | thymosin beta 4, X-linked | 0.078626 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0755266 |
| GOLGA4 | golgin A4 | 0.0707748 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.067956 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0659414 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0616111 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0614748 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0574204 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0552493 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0524414 |
| SNX9 | sorting nexin 9 | 0.0520479 |
| SET | SET nuclear proto-oncogene | 0.0489681 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0487949 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0472463 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0469714 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0457938 |
| PCBP2 | poly(rC) binding protein 2 | 0.0454952 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0448913 |
| RBM39 | RNA binding motif protein 39 | 0.0442359 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0433638 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0430262 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0426394 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0425413 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0420274 |
| RAB1A | RAB1A, member RAS oncogene family | 0.04185 |
| BRD2 | bromodomain containing 2 | 0.0417708 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415325 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0414111 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0409912 |
| XPO1 | exportin 1 | 0.0409908 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0399425 |
| RHEB | Ras homolog enriched in brain | 0.0397483 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0387375 |
| RYBP | RING1 and YY1 binding protein | 0.0380121 |
| CCNL1 | cyclin L1 | 0.0379735 |
| SUCO | SUN domain containing ossification factor | 0.0378137 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0374986 |
| ZNF292 | zinc finger protein 292 | 0.0374518 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373289 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0367578 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0361952 |
| RPL14 | ribosomal protein L14 | 0.0359249 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0357882 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0354745 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0346158 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0345778 |
| NEK7 | NIMA-related kinase 7 | 0.0344095 |
| NCKAP1 | NCK-associated protein 1 | 0.0334748 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0333734 |
| JMJD1C | jumonji domain containing 1C | 0.0330768 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0328798 |
| OGA | O-GlcNAcase | 0.032654 |
| TFG | TRK-fused gene | 0.0324667 |
| ACTN4 | actinin, alpha 4 | 0.0321942 |
| SDC4 | syndecan 4 | 0.0320455 |
| MTMR3 | myotubularin related protein 3 | 0.0319826 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0319104 |
| CUL3 | cullin 3 | 0.0319028 |
| TMF1 | TATA element modulatory factor 1 | 0.0318922 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0316721 |
| CALR | calreticulin | 0.031647 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0315897 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0315135 |
| PDS5B | PDS5 cohesin associated factor B | 0.0314601 |
| DSPP | dentin sialophosphoprotein | 0.0308634 |
| VMP1 | vacuole membrane protein 1 | 0.0305594 |
| FNBP1L | formin binding protein 1-like | 0.0300781 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0300139 |
| SPAG9 | sperm associated antigen 9 | 0.029906 |
| MYO6 | myosin VI | 0.029845 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0295507 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0292806 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0291619 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0289486 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0288825 |
| MEF2A | myocyte enhancer factor 2A | 0.0287849 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0285876 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0285469 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0282737 |
| CYTH3 | cytohesin 3 | 0.0280119 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0279222 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0278661 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0276629 |
| ANLN | anillin, actin binding protein | 0.0276142 |
| MED13L | mediator complex subunit 13-like | 0.0275974 |
| RBM33 | RNA binding motif protein 33 | 0.027507 |
| PGK1 | phosphoglycerate kinase 1 | 0.027291 |
| CEP192 | centrosomal protein 192kDa | 0.0270559 |
| JAK1 | Janus kinase 1 | 0.027005 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.026955 |
| ANXA11 | annexin A11 | 0.0268499 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0266826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0787023 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0752148 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0741186 |
| RPL35A | ribosomal protein L35a | -0.0693134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0588428 |
| RPLP1 | ribosomal protein, large, P1 | -0.0548565 |
| EHBP1 | EH domain binding protein 1 | -0.0531461 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0518895 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0510968 |
| CADPS | Ca++-dependent secretion activator | -0.0503655 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0503422 |
| PKP4 | plakophilin 4 | -0.0486108 |
| FRMD5 | FERM domain containing 5 | -0.0472358 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0442019 |
| EGR1 | early growth response 1 | -0.0426433 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0420464 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0418822 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0403133 |
| BCL2L1 | BCL2-like 1 | -0.0400703 |
| NRP1 | neuropilin 1 | -0.0396451 |
| RNF213 | ring finger protein 213 | -0.0393685 |
| PTMA | prothymosin, alpha | -0.039363 |
| RAD51B | RAD51 paralog B | -0.0386336 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0382193 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.037671 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0375709 |
| RPL23 | ribosomal protein L23 | -0.0374416 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0370155 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0367642 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0358697 |
| IER3 | immediate early response 3 | -0.0357093 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0351685 |
| GNAS | GNAS complex locus | -0.0349844 |
| TMSB10 | thymosin beta 10 | -0.0347637 |
| FAT1 | FAT atypical cadherin 1 | -0.0342043 |
| ETV6 | ets variant 6 | -0.0330529 |
| NEBL | nebulette | -0.0323238 |
| H1-0 | H1.0 linker histone | -0.0322884 |
| RNF43 | ring finger protein 43 | -0.0313159 |
| RPL28 | ribosomal protein L28 | -0.031086 |
| MX2 | MX dynamin-like GTPase 2 | -0.0310331 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0309742 |
| PLSCR1 | phospholipid scramblase 1 | -0.0308652 |
| GPHN | gephyrin | -0.0307893 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0307157 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0300669 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0298718 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0293694 |
| PRELID2 | PRELI domain containing 2 | -0.0291487 |
| RUNX1 | runt-related transcription factor 1 | -0.0288875 |
| RIGI | RNA sensor RIG-I | -0.0287777 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0282055 |
| RPS25 | ribosomal protein S25 | -0.0280514 |
| NHSL1 | NHS-like 1 | -0.0279177 |
| CDK13 | cyclin-dependent kinase 13 | -0.0279026 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0278303 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0274748 |
| SP100 | SP100 nuclear antigen | -0.0274408 |
| WWOX | WW domain containing oxidoreductase | -0.027379 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0273384 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0272853 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0272404 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0271343 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0270396 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0269352 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0268977 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.026764 |
| EXOC4 | exocyst complex component 4 | -0.0265772 |
| NUP98 | nucleoporin 98kDa | -0.0263306 |
| ZNRF3 | zinc and ring finger 3 | -0.0262188 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0260974 |
| INTS6 | integrator complex subunit 6 | -0.0260766 |
| HM13 | histocompatibility (minor) 13 | -0.0259599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0258144 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0257663 |
| USP34 | ubiquitin specific peptidase 34 | -0.0255693 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0255484 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0255086 |
| HLA-A | major histocompatibility complex, class I, A | -0.0251294 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0250413 |
| CUX1 | cut-like homeobox 1 | -0.0250303 |
| RPLP0 | ribosomal protein, large, P0 | -0.0249878 |
| RPL19 | ribosomal protein L19 | -0.0248573 |
| TXNIP | thioredoxin interacting protein | -0.0243688 |
| PERP | PERP, TP53 apoptosis effector | -0.0243549 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0242746 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0241454 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0238553 |
| HMGB1 | high mobility group box 1 | -0.0236146 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0234468 |
| DACH1 | dachshund family transcription factor 1 | -0.0234397 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.02342 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0233615 |
| DIAPH2 | diaphanous-related formin 2 | -0.0232036 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0231798 |
| EGFR | epidermal growth factor receptor | -0.0231583 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0231132 |
| RPS11 | ribosomal protein S11 | -0.0229985 |
| RPS5 | ribosomal protein S5 | -0.0229391 |
| ATG7 | autophagy related 7 | -0.0227211 |
