| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Indacaterol (maleate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.118609 |
| LMO7 | LIM domain 7 | 0.0916238 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0909271 |
| GOLGA4 | golgin A4 | 0.0909182 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0861754 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0833843 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0820678 |
| TXNRD1 | thioredoxin reductase 1 | 0.0749431 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0693665 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0663437 |
| OXR1 | oxidation resistance 1 | 0.0657197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0589712 |
| RNF43 | ring finger protein 43 | 0.0558653 |
| EREG | epiregulin | 0.0551764 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0543429 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0537347 |
| RUNX2 | runt-related transcription factor 2 | 0.0533387 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0521224 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0490339 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0481914 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0474722 |
| MED13L | mediator complex subunit 13-like | 0.0468694 |
| ANXA1 | annexin A1 | 0.0460943 |
| TOP1 | topoisomerase (DNA) I | 0.045985 |
| RNF145 | ring finger protein 145 | 0.0457101 |
| OGA | O-GlcNAcase | 0.0454145 |
| FAT1 | FAT atypical cadherin 1 | 0.0442467 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0434735 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0434123 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0427346 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0425425 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0416377 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0415534 |
| EZR | ezrin | 0.0414795 |
| NUP58 | nucleoporin 58 | 0.0400044 |
| RANBP9 | RAN binding protein 9 | 0.0393371 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0387199 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.036597 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.0362377 |
| CCNL1 | cyclin L1 | 0.0358955 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0358329 |
| ZNF292 | zinc finger protein 292 | 0.0357169 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0352079 |
| COPA | coatomer protein complex, subunit alpha | 0.035084 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0343822 |
| RPS6 | ribosomal protein S6 | 0.0342963 |
| USP6NL | USP6 N-terminal like | 0.0341538 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0340594 |
| WDR43 | WD repeat domain 43 | 0.0334407 |
| USP3 | ubiquitin specific peptidase 3 | 0.0332454 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0327302 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0326953 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0325694 |
| NCKAP1 | NCK-associated protein 1 | 0.0321311 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0320446 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0318613 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.031627 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0314802 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0313075 |
| YAP1 | Yes-associated protein 1 | 0.0311857 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0311687 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0311162 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0308245 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0308234 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0308225 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0304638 |
| EGFR | epidermal growth factor receptor | 0.0301327 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0295663 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0295051 |
| COG5 | component of oligomeric golgi complex 5 | 0.029159 |
| NEK7 | NIMA-related kinase 7 | 0.0290658 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0290353 |
| ANXA11 | annexin A11 | 0.028964 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.028883 |
| RBM39 | RNA binding motif protein 39 | 0.0288269 |
| ZNRF3 | zinc and ring finger 3 | 0.0285957 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0283974 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0283881 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0282071 |
| RTN4 | reticulon 4 | 0.0278065 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0276057 |
| ECT2 | epithelial cell transforming 2 | 0.0274027 |
| ATP11B | ATPase, class VI, type 11B | 0.0273751 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0273712 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0272513 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0272375 |
| SPAG9 | sperm associated antigen 9 | 0.0271279 |
| TNPO1 | transportin 1 | 0.0268042 |
| CDC73 | cell division cycle 73 | 0.0266374 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0265336 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0258825 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0253665 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0252724 |
| XPO1 | exportin 1 | 0.0250395 |
| YBX1 | Y box binding protein 1 | 0.0249564 |
| INSIG2 | insulin induced gene 2 | 0.024955 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0248752 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0247652 |
| RPS19 | ribosomal protein S19 | 0.0244878 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0244868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.142043 |
| HMGA2 | high mobility group AT-hook 2 | -0.124817 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.103027 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0939686 |
| RAD51B | RAD51 paralog B | -0.0855295 |
| FHIT | fragile histidine triad | -0.0814691 |
| LAMB3 | laminin, beta 3 | -0.0780799 |
| VCL | vinculin | -0.0754745 |
| LAMA4 | laminin, alpha 4 | -0.0648293 |
| EGR1 | early growth response 1 | -0.063048 |
| RCOR1 | REST corepressor 1 | -0.0573332 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0500722 |
| GPC5 | glypican 5 | -0.050049 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0465636 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.044873 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.044583 |
| EXOC4 | exocyst complex component 4 | -0.0430903 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0430358 |
| FHL2 | four and a half LIM domains 2 | -0.0417071 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0408286 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0387596 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0382098 |
| RPS24 | ribosomal protein S24 | -0.0364634 |
| AHNAK | AHNAK nucleoprotein | -0.035397 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0351338 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0336568 |
| MTAP | methylthioadenosine phosphorylase | -0.0331379 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0320492 |
| IER3 | immediate early response 3 | -0.031669 |
| FLOT1 | flotillin 1 | -0.0315416 |
| EFNB2 | ephrin-B2 | -0.0312783 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0311662 |
| CUX1 | cut-like homeobox 1 | -0.0305734 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0302233 |
| CMIP | c-Maf inducing protein | -0.0292311 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0289318 |
| EHBP1 | EH domain binding protein 1 | -0.0288043 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0284083 |
| RPL35A | ribosomal protein L35a | -0.0281501 |
| RASAL2 | RAS protein activator like 2 | -0.0279474 |
| SGMS2 | sphingomyelin synthase 2 | -0.0270945 |
| CREB5 | cAMP responsive element binding protein 5 | -0.027084 |
| CDK13 | cyclin-dependent kinase 13 | -0.0264555 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0264523 |
| ABR | active BCR-related | -0.0256868 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0255772 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0248934 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0248253 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0236976 |
| ANXA2 | annexin A2 | -0.0236731 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0235312 |
| ITGB4 | integrin, beta 4 | -0.0233277 |
| RPL34 | ribosomal protein L34 | -0.0229839 |
| CDHR3 | cadherin-related family member 3 | -0.0229629 |
| NUP50 | nucleoporin 50kDa | -0.0228756 |
| WWOX | WW domain containing oxidoreductase | -0.0226156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0221492 |
| CANX | calnexin | -0.0219111 |
| EMP1 | epithelial membrane protein 1 | -0.0218608 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.021795 |
| PCNX4 | pecanex 4 | -0.0215243 |
| HDAC4 | histone deacetylase 4 | -0.0215231 |
| ARF1 | ADP-ribosylation factor 1 | -0.0211798 |
| INTS6 | integrator complex subunit 6 | -0.02113 |
| TENM3 | teneurin transmembrane protein 3 | -0.0202167 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0200689 |
| KRT18 | keratin 18, type I | -0.0199816 |
| AEBP2 | AE binding protein 2 | -0.0198831 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.019879 |
| S100A10 | S100 calcium binding protein A10 | -0.0193857 |
| MYO1E | myosin IE | -0.0192279 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0192092 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0191024 |
| FOXP1 | forkhead box P1 | -0.0190233 |
| SMAD3 | SMAD family member 3 | -0.0188595 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0186933 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0186842 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0186824 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0184539 |
| UBAP2 | ubiquitin associated protein 2 | -0.0184311 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0184002 |
| SMYD3 | SET and MYND domain containing 3 | -0.01832 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0181386 |
| DSG2 | desmoglein 2 | -0.018001 |
| UBC | ubiquitin C | -0.0179219 |
| RSU1 | Ras suppressor protein 1 | -0.0179214 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0175827 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0175462 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0174999 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0174304 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0173641 |
| SEPTIN9 | septin 9 | -0.0173126 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0171079 |
| BPTF | bromodomain PHD finger transcription factor | -0.0170254 |
| S100A6 | S100 calcium binding protein A6 | -0.0169053 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0166779 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0164351 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0164033 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0161723 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0161719 |
