| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Indacaterol (maleate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Indacaterol (maleate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | 0.161641 |
| STC1 | stanniocalcin 1 | 0.155474 |
| B2M | beta-2-microglobulin | 0.130789 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.107312 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0981988 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0709825 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.063094 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0566757 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0547456 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0454174 |
| HLA-B | major histocompatibility complex, class I, B | 0.0441583 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0401265 |
| MT2A | metallothionein 2A | 0.0378343 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0375625 |
| TOP1 | topoisomerase (DNA) I | 0.0374034 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0371051 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0371028 |
| RPS6 | ribosomal protein S6 | 0.0357065 |
| FMNL2 | formin-like 2 | 0.0353906 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.035362 |
| RPL37A | ribosomal protein L37a | 0.0343966 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0322808 |
| TMSB10 | thymosin beta 10 | 0.0319799 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0311729 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0311652 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0308048 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.030246 |
| RASA2 | RAS p21 protein activator 2 | 0.0297326 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0287131 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0283258 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0278894 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0278601 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0268258 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0262848 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0261326 |
| MYO10 | myosin X | 0.0259184 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0251074 |
| PTMA | prothymosin, alpha | 0.0242864 |
| OGA | O-GlcNAcase | 0.0237204 |
| RPL35A | ribosomal protein L35a | 0.0236241 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0235932 |
| SPAG9 | sperm associated antigen 9 | 0.023351 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0232196 |
| VMP1 | vacuole membrane protein 1 | 0.0227596 |
| PCBP3 | poly(rC) binding protein 3 | 0.0226522 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0225593 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0225146 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.022271 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0220832 |
| SNX9 | sorting nexin 9 | 0.0219452 |
| CUL3 | cullin 3 | 0.0216087 |
| XPO1 | exportin 1 | 0.0213559 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213348 |
| CD44 | CD44 molecule (Indian blood group) | 0.0211404 |
| TMEM51 | transmembrane protein 51 | 0.020754 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0207393 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0206672 |
| CDK19 | cyclin-dependent kinase 19 | 0.0205821 |
| GOLGA4 | golgin A4 | 0.020562 |
| NBAS | neuroblastoma amplified sequence | 0.0204712 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0204246 |
| ZNF451 | zinc finger protein 451 | 0.0203866 |
| USP34 | ubiquitin specific peptidase 34 | 0.0203414 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0202994 |
| EMP1 | epithelial membrane protein 1 | 0.0196067 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0193659 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0193135 |
| RNF145 | ring finger protein 145 | 0.0192528 |
| WTAP | Wilms tumor 1 associated protein | 0.0191679 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0190876 |
| PTK2 | protein tyrosine kinase 2 | 0.0190405 |
| GPATCH2L | G patch domain containing 2-like | 0.0190355 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0189259 |
| FOXO3 | forkhead box O3 | 0.0187912 |
| RPS12 | ribosomal protein S12 | 0.0187799 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.018775 |
| TEX10 | testis expressed 10 | 0.018759 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0187208 |
| G0S2 | G0/G1 switch 2 | 0.0187034 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0186868 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0186137 |
| NAV2 | neuron navigator 2 | 0.0184689 |
| RLF | rearranged L-myc fusion | 0.0180885 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.017907 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0178385 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0178208 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0177654 |
| COPA | coatomer protein complex, subunit alpha | 0.0174371 |
| SUCO | SUN domain containing ossification factor | 0.0171069 |
| COG6 | component of oligomeric golgi complex 6 | 0.0170315 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0170246 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0168146 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0166892 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0165512 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.01647 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0163179 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0162968 |
| CDC27 | cell division cycle 27 | 0.0162467 |
| DENND4C | DENN/MADD domain containing 4C | 0.0161707 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0160788 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.305966 |
| FN1 | fibronectin 1 | -0.29487 |
| COL6A3 | collagen, type VI, alpha 3 | -0.245444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139251 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.137652 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131418 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.103755 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.096448 |
| HMGA2 | high mobility group AT-hook 2 | -0.0956282 |
| FBN1 | fibrillin 1 | -0.0902683 |
| DST | dystonin | -0.0799477 |
| COL1A1 | collagen, type I, alpha 1 | -0.0770068 |
| AHNAK | AHNAK nucleoprotein | -0.0657441 |
| MAP1B | microtubule-associated protein 1B | -0.0612721 |
| NDRG1 | N-myc downstream regulated 1 | -0.0607294 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0597969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0562914 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0509831 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0468552 |
| LOX | lysyl oxidase | -0.0441356 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0438057 |
| RNF213 | ring finger protein 213 | -0.0414941 |
| CANX | calnexin | -0.0412575 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0409873 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0392211 |
| CALR | calreticulin | -0.0375184 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0372475 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0360286 |
| CCND1 | cyclin D1 | -0.0359296 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0355498 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0351305 |
| ANXA2 | annexin A2 | -0.0343749 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0343117 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0341383 |
| DPYD | dihydropyrimidine dehydrogenase | -0.033349 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0328327 |
| HHIP | hedgehog interacting protein | -0.0326806 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0322543 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0318132 |
| LMAN1 | lectin, mannose-binding, 1 | -0.031725 |
| COL5A1 | collagen, type V, alpha 1 | -0.0314595 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0313402 |
| TPM1 | tropomyosin 1 (alpha) | -0.0305556 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0305536 |
| LDHA | lactate dehydrogenase A | -0.0305165 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0302719 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0301528 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0299548 |
| CALD1 | caldesmon 1 | -0.0293722 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0293626 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0293435 |
| VIM | vimentin | -0.0290541 |
| VEGFC | vascular endothelial growth factor C | -0.0290402 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0290086 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0286416 |
| RND3 | Rho family GTPase 3 | -0.0285725 |
| FOXP1 | forkhead box P1 | -0.0273819 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0271806 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0270835 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0268952 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0266788 |
| RAI14 | retinoic acid induced 14 | -0.0266694 |
| KLF12 | Kruppel-like factor 12 | -0.0261171 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.025659 |
| TCF12 | transcription factor 12 | -0.0256058 |
| FTL | ferritin, light polypeptide | -0.025334 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0253153 |
| ANKRD28 | ankyrin repeat domain 28 | -0.025296 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0252413 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0249342 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0248828 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0247513 |
| RASAL2 | RAS protein activator like 2 | -0.0244358 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0244026 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0243971 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0237333 |
| BPTF | bromodomain PHD finger transcription factor | -0.0234163 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0232992 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0232814 |
| ENO1 | enolase 1, (alpha) | -0.0232282 |
| JAZF1 | JAZF zinc finger 1 | -0.0229076 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0228041 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0223276 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0222937 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022176 |
| PRSS23 | protease, serine, 23 | -0.0221021 |
| ITGA11 | integrin, alpha 11 | -0.021901 |
| UTRN | utrophin | -0.0216167 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0215507 |
| NAV1 | neuron navigator 1 | -0.0213479 |
| EGFR | epidermal growth factor receptor | -0.0212785 |
| LYST | lysosomal trafficking regulator | -0.0211802 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0211506 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0210387 |
| ATM | ATM serine/threonine kinase | -0.0210348 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0208079 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0206452 |
| SEC24D | SEC24 family member D | -0.020409 |
| EXOC4 | exocyst complex component 4 | -0.0203667 |
| EHBP1 | EH domain binding protein 1 | -0.0202843 |
